School wellbeing among children in grades 1 - 10

<p>Abstract</p> <p>Background</p> <p>Determinants of children's school wellbeing have not been extensively studied. In this cross-sectional study of school children we assessed how factors assumed to promote wellbeing and factors assumed to adversely influence wellbeing were associated with self-reported wellbeing in school.</p> <p>Methods</p> <p>Children from five schools, 230 boys and 189 girls in grades 1-10, responded to the same set of questions. We used proportional odds logistic regression to assess the associations of promoting and restraining factors with school wellbeing.</p> <p>Results</p> <p>In a multivariable analysis, degree of school wellbeing in boys was strongly and positively related to enjoying school work (odds ratio, 3.84, 95% CI 2.38 to 6.22) and receiving necessary help (odds ratio, 3.55, 95% CI 2.17 to 5.80) from teachers. In girls, being bothered during lessons was strongly and negatively associated with school wellbeing (odds ratio, 0.43, 95% CI 0.22 to 0.85).</p> <p>Conclusions</p> <p>Different factors may determine school wellbeing in boys and girls, but for both genders, factors relevant for lessons may be more important than factors related to recess. Especially in boys, the student-teacher relationship may be of particular importance.</p

Matrix Metalloproteinases in Cytotoxic Lymphocytes Impact on Tumour Infiltration and Immunomodulation

To efficiently combat solid tumours, endogenously or adoptively transferred cytotoxic T cells and natural killer (NK) cells, need to leave the vasculature, traverse the interstitium and ultimately infiltrate the tumour mass. During this locomotion and migration in the three dimensional environment many obstacles need to be overcome, one of which is the possible impediment of the extracellular matrix. The first and obvious one is the sub-endothelial basement membrane but the infiltrating cells will also meet other, both loose and tight, matrix structures that need to be overridden. Matrix metalloproteinases (MMPs) are believed to be one of the most important endoprotease families, with more than 25 members, which together have function on all known matrix components. This review summarizes what is known on synthesis, expression patterns and regulation of MMPs in cytotoxic lymphocytes and their possible role in the process of tumour infiltration. We also discuss different functions of MMPs as well as the possible use of other lymphocyte proteases for matrix degradation

Do classes and schools have an effect on attitudes towards mathematics?

12status: publishe

Teacher-student interpersonal relationships during the first year of secondary education : a multilevel growth curve analysis

This paper presents an illustration of a developmental trend of teacher-students interpersonal relationship in Mathematics and English classes during the first year of secondary education. Students perceptions were gathered using the Questionnaire on Teacher Interaction (QTI) and were mapped in terms of two dimensions: Influence and Proximity. Measures were taken four times a year, from 566 students of 20 Mathematics and English classes, from 3 Dutch secondary schools. The preliminary results show that teacher-students interpersonal relationships decrease continuously throughout the school year: a dramatic change is more evident for Proximity than that for Influence. In addition, there is an indication that students perceptions seemed to change from occasion to occasion during a school year

Teacher-student interpersonal behavior in secundary mathematics classes in Indonesia

This study is aimed at describing profiles of interpersonal behavior of Indonesian mathematics teachers and examining associations between students’ perceptions of their mathematics teachers’ interpersonal behavior and their motivation in learning mathematics. Data were collected with the Indonesian version of the Questionnaire on Teacher Interaction (QTI) and the Questionnaire on Motivational Dimensions. The framework of this study is based on the Model of Interpersonal Behavior that maps teachers’ conduct in terms of 2 dimensions: Influence (Dominance–Submission) and Proximity (Cooperation–Opposition). A total of 506 students (grades 7 to 9) from 16 classes in 5 public secondary schools in the West Java and Jambi provinces, Indonesia, participated in the study. Data analyses were conducted including descriptive, correlational, and multilevel analyses. Results from the data analyses showed that the reliability and (validity) of the Indonesian QTI were good; teachers’ ratings of their interpersonal behavior were moderate in class perceptions but (were) quite high in teachers’ self-perception in both the Proximity and Influence dimensions and that associations existed between the 2 dimensions of interpersonal behavior and student motivation in learning mathematics. There was an indication that Indonesian mathematics teachers were generally perceived as directive. Implications of the findings were discussed