4,417 research outputs found
Measurement-induced generation of spatial entanglement in a two-dimensional quantum walk with single-qubit coin
One of the proposals for the exploitation of two-dimensional quantum walks
has been the efficient generation of entanglement. Unfortunately, the
technological effort required for the experimental realization of standard
two-dimensional quantum walks is significantly demanding. In this respect, an
alternative scheme with less challenging conditions has been recently studied,
particularly in terms of spatial-entanglement generation [C. Di Franco, M. Mc
Gettrick, and Th. Busch, Phys. Rev. Lett. 106, 080502 (2011)]. Here, we extend
the investigation to a scenario where a measurement is performed on the coin
degree of freedom after the evolution, allowing a further comparison with the
standard two-dimensional Grover walk.Comment: 9 pages, 4 figures, RevTeX
Alternate two-dimensional quantum walk with a single-qubit coin
We have recently proposed a two-dimensional quantum walk where the
requirement of a higher dimensionality of the coin space is substituted with
the alternance of the directions in which the walker can move [C. Di Franco, M.
Mc Gettrick, and Th. Busch, Phys. Rev. Lett. {\bf 106}, 080502 (2011)]. For a
particular initial state of the coin, this walk is able to perfectly reproduce
the spatial probability distribution of the non-localized case of the Grover
walk. Here, we present a more detailed proof of this equivalence. We also
extend the analysis to other initial states, in order to provide a more
complete picture of our walk. We show that this scheme outperforms the Grover
walk in the generation of - spatial entanglement for any initial
condition, with the maximum entanglement obtained in the case of the particular
aforementioned state. Finally, the equivalence is generalized to wider classes
of quantum walks and a limit theorem for the alternate walk in this context is
presented.Comment: 9 pages, 9 figures, RevTeX
Hypovitaminosis D in recent onset rheumatoid arthritis is predictive of reduced response to treatment and increased disease activity: a 12 month follow-up study.
BACKGROUND:
Vitamin D displays immunomodulatory activities and has been proposed as a potential player in the pathogenesis of rheumatoid arthritis (RA). A negative association between serum 25(OH) vitamin D levels and RA activity was demonstrated but longitudinal studies investigating the role of vitamin D levels in predicting RA activity and response to treatment are lacking. Therefore, this study was designed to test the hypothesis of an association between serum 25(OH) vitamin D levels at RA diagnosis and disease activity evaluated by clinimetric, laboratory and ultrasound (US) parameters and to detect the prevalence of remission and response to treatment after 12 months follow-up.
METHODS:
This is a longitudinal, retrospective study on data obtained from thirty-seven patients with early RA treatment-naïve. Serum inflammatory markers, auto-antibodies and 25(OH) vitamin D levels were obtained at baseline. Hypovitaminosis D was diagnosed for 25(OH) vitamin D levels < 20 ng/ml. Tender joint count (TJCs), swollen joint count (SJCs), Visual Analog Scales (VAS), Disease Activity Score (DAS) 28 score were assessed at baseline and 12 months after diagnosis. Joints synovitis and power-Doppler were evaluated at baseline and 12 months later.
RESULTS:
At baseline mean 25(OH) vitamin D levels were 24.4 ± 11.9 ng/ml; 35% of study subjects had hypovitaminosis D which strongly associated with higher RA activity and lower prevalence of remission and response to treatment (all p-values < 0.001). The percentage of patients not presenting a reduction of the US synovitis score after 12 months from diagnosis was significantly higher among patients with hypovitaminosis D than in those with normal serum 25(OH) vitamin D at baseline.
CONCLUSIONS:
In patients with early RA and basal hypovitaminosis D after 12 months follow-up reduction of disease activity and percentage of remission and response to treatment were significantly lower than those observed in patients with normal vitamin D levels. These results provide further support to the immunomodulatory action of vitamin D in RA and suggest a role of basal vitamin D status in the prediction of disease evolution. Vitamin D measurement and possibly vitamin D supplementation should be considered an additional option in the management of early RA patients
Mimicking the probability distribution of a two-dimensional Grover walk with a single-qubit coin
Multi-dimensional quantum walks usually require large coin spaces. Here we
show that the non-localized case of the spatial density probability of the
two-dimensional Grover walk can be obtained using only a two-dimensional coin
space and a quantum walk in alternate directions. We present a formal proof of
this correspondence and analyze the behavior of the coin-position entanglement
as well as the x-y spatial entanglement in our scheme with respect to the
Grover one. We show that our experimentally simpler scheme allows to entangle
the two orthogonal directions of the walk more efficiently.Comment: 5 pages, 2 figures, RevTeX
Observing Brownian motion in vibration-fluidized granular matter
At the beginning of last century, Gerlach and Lehrer observed the rotational
Brownian motion of a very fine wire immersed in an equilibrium environment, a
gas. This simple experiment eventually permitted the full development of one of
the most important ideas of equilibrium statistical mechanics: the very
complicated many-particle problem of a large number of molecules colliding with
the wire, can be represented by two macroscopic parameters only, namely
viscosity and the temperature. Can this idea, mathematically developed in the
so-called Langevin model and the fluctuation-dissipation theorem be used to
describe systems that are far from equilibrium? Here we address the question
and reproduce the Gerlach and Lehrer experiment in an archetype non-equilibrium
system, by immersing a sensitive torsion oscillator in a granular system of
millimetre-size grains, fluidized by strong external vibrations. The
vibro-fluidized granular medium is a driven environment, with continuous
injection and dissipation of energy, and the immersed oscillator can be seen as
analogous to an elastically bound Brownian particle. We show, by measuring the
noise and the susceptibility, that the experiment can be treated, in first
approximation, with the same formalism as in the equilibrium case, giving
experimental access to a ''granular viscosity'' and an ''effective
temperature'', however anisotropic and inhomogeneous, and yielding the
surprising result that the vibro-fluidized granular matter behaves as a
''thermal'' bath satisfying a fluctuation-dissipation relation
Dense active matter model of motion patterns in confluent cell monolayers
Epithelial cell monolayers show remarkable displacement and velocity
correlations over distances of ten or more cell sizes that are reminiscent of
supercooled liquids and active nematics. We show that many observed features
can be described within the framework of dense active matter, and argue that
persistent uncoordinated cell motility coupled to the collective elastic modes
of the cell sheet is sufficient to produce swirl-like correlations. We obtain
this result using both continuum active linear elasticity and a normal modes
formalism, and validate analytical predictions with numerical simulations of
two agent-based cell models, soft elastic particles and the self-propelled
Voronoi model together with in-vitro experiments of confluent corneal
epithelial cell sheets. Simulations and normal mode analysis perfectly match
when tissue-level reorganisation occurs on times longer than the persistence
time of cell motility. Our analytical model quantitatively matches measured
velocity correlation functions over more than a decade with a single fitting
parameter.Comment: updated version accepted for publication in Nat. Com
Synthesis of titanate nanostructures using amorphous precursor material and their adsorption/photocatalytic properties
This paper reports on a new and swift hydrothermal chemical route to prepare
titanate nanostructures (TNS) avoiding the use of crystalline TiO2 as starting
material. The synthesis approach uses a commercial solution of TiCl3 as
titanium source to prepare an amorphous precursor, circumventing the use of
hazardous chemical compounds. The influence of the reaction temperature and
dwell autoclave time on the structure and morphology of the synthesised
materials was studied. Homogeneous titanate nanotubes with a high
length/diameter aspect ratio were synthesised at 160^{\circ}C and 24 h. A band
gap of 3.06\pm0.03 eV was determined for the TNS samples prepared in these
experimental conditions. This value is red shifted by 0.14 eV compared to the
band gap value usually reported for the TiO2 anatase. Moreover, such samples
show better adsorption capacity and photocatalytic performance on the dye
rhodamine 6G (R6G) photodegradation process than TiO2 nanoparticles. A 98%
reduction of the R6G concentration was achieved after 45 minutes of irradiation
of a 10 ppm dye aqueous solution and 1 g/L of TNS catalyst.Comment: 29 pages, 10 figures, accepted for publication in Journal of
Materials Scienc
Overview on the phenomenon of two-qubit entanglement revivals in classical environments
The occurrence of revivals of quantum entanglement between separated open
quantum systems has been shown not only for dissipative non-Markovian quantum
environments but also for classical environments in absence of back-action.
While the phenomenon is well understood in the first case, the possibility to
retrieve entanglement when the composite quantum system is subject to local
classical noise has generated a debate regarding its interpretation. This
dynamical property of open quantum systems assumes an important role in quantum
information theory from both fundamental and practical perspectives. Hybrid
quantum-classical systems are in fact promising candidates to investigate the
interplay among quantum and classical features and to look for possible control
strategies of a quantum system by means of a classical device. Here we present
an overview on this topic, reporting the most recent theoretical and
experimental results about the revivals of entanglement between two qubits
locally interacting with classical environments. We also review and discuss the
interpretations provided so far to explain this phenomenon, suggesting that
they can be cast under a unified viewpoint.Comment: 16 pages, 9 figures. Chapter written for the upcoming book "Lectures
on general quantum correlations and their applications
Birthweight and risk markers for type 2 diabetes and cardiovascular disease in childhood: the Child Heart and Health Study in England (CHASE).
AIMS/HYPOTHESIS: Lower birthweight (a marker of fetal undernutrition) is associated with higher risks of type 2 diabetes and cardiovascular disease (CVD) and could explain ethnic differences in these diseases. We examined associations between birthweight and risk markers for diabetes and CVD in UK-resident white European, South Asian and black African-Caribbean children.
METHODS: In a cross-sectional study of risk markers for diabetes and CVD in 9- to 10-year-old children of different ethnic origins, birthweight was obtained from health records and/or parental recall. Associations between birthweight and risk markers were estimated using multilevel linear regression to account for clustering in children from the same school.
RESULTS: Key data were available for 3,744 (66%) singleton study participants. In analyses adjusted for age, sex and ethnicity, birthweight was inversely associated with serum urate and positively associated with systolic BP. After additional height adjustment, lower birthweight (per 100 g) was associated with higher serum urate (0.52%; 95% CI 0.38, 0.66), fasting serum insulin (0.41%; 95% CI 0.08, 0.74), HbA1c (0.04%; 95% CI 0.00, 0.08), plasma glucose (0.06%; 95% CI 0.02, 0.10) and serum triacylglycerol (0.30%; 95% CI 0.09, 0.51) but not with BP or blood cholesterol. Birthweight was lower among children of South Asian (231 g lower; 95% CI 183, 280) and black African-Caribbean origin (81 g lower; 95% CI 30, 132). However, adjustment for birthweight had no effect on ethnic differences in risk markers.
CONCLUSIONS/INTERPRETATION: Birthweight was inversely associated with urate and with insulin and glycaemia after adjustment for current height. Lower birthweight does not appear to explain emerging ethnic difference in risk markers for diabetes
Mass hierarchy discrimination with atmospheric neutrinos in large volume ice/water Cherenkov detectors
Large mass ice/water Cherenkov experiments, optimized to detect low energy
(1-20 GeV) atmospheric neutrinos, have the potential to discriminate between
normal and inverted neutrino mass hierarchies. The sensitivity depends on
several model and detector parameters, such as the neutrino flux profile and
normalization, the Earth density profile, the oscillation parameter
uncertainties, and the detector effective mass and resolution. A proper
evaluation of the mass hierarchy discrimination power requires a robust
statistical approach. In this work, the Toy Monte Carlo, based on an extended
unbinned likelihood ratio test statistic, was used. The effect of each model
and detector parameter, as well as the required detector exposure, was then
studied. While uncertainties on the Earth density and atmospheric neutrino flux
profiles were found to have a minor impact on the mass hierarchy
discrimination, the flux normalization, as well as some of the oscillation
parameter (\Delta m^2_{31}, \theta_{13}, \theta_{23}, and \delta_{CP})
uncertainties and correlations resulted critical. Finally, the minimum required
detector exposure, the optimization of the low energy threshold, and the
detector resolutions were also investigated.Comment: 23 pages, 16 figure
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