751 research outputs found
Noncommutative Yang-Mills-Higgs actions from derivation-based differential calculus
Derivations of a noncommutative algebra can be used to construct differential
calculi, the so-called derivation-based differential calculi. We apply this
framework to a version of the Moyal algebra . We show that the
differential calculus, generated by the maximal subalgebra of the derivation
algebra of that can be related to infinitesimal symplectomorphisms,
gives rise to a natural construction of Yang-Mills-Higgs models on
and a natural interpretation of the covariant coordinates as Higgs fields. We
also compare in detail the main mathematical properties characterizing the
present situation to those specific of two other noncommutative geometries,
namely the finite dimensional matrix algebra and the
algebra of matrix valued functions . The
UV/IR mixing problem of the resulting Yang-Mills-Higgs models is also
discussed.Comment: 23 pages, 2 figures. Improved and enlarged version. Some references
have been added and updated. Two subsections and a discussion on the
appearence of Higgs fiels in noncommutative gauge theories have been adde
Decision Making in Near Zero Energy Building Refurbishment: A Technology Alternatives Ranking Tool
International audienceDecision making in the context of Near Zero Energy Building refurbishment is subjected to heterogeneous stakeholders, tools and objectives. This paper presents a methodology to facilitate stakeholders collaboration in the refurbishment processes and identifies decision support approaches to help on the main decision milestones. This methodology is supported by a prototype (user interface and algorithm) of a decision support system (DSS) that allows ranking different refurbishment technologies. The proposed DSS uses a multi criteria decision method that combines weighting and fuzzy dominances approach. The approach is illustrated with a real data set to rank insulation materials
ComPASS: a tool for distributed parallel finite volume discretizations on general unstructured polyhedral meshes
International audienceThe objective of the ComPASS project is to develop a parallel multiphase Darcy flow simulator adapted to general unstructured polyhedral meshes (in a general sense with possibly non planar faces) and to the parallelization of advanced finite volume discretizations with various choices of the degrees of freedom such as cell centres, vertices, or face centres. The main targeted applications are the simulation of CO2 geological storage, nuclear waste repository and reservoir simulations. The CEMRACS 2012 summer school devoted to high performance computing has been an ideal framework to start this collaborative project. This paper describes what has been achieved during the four weeks of the CEMRACS project which has been focusing on the implementation of basic features of the code such as the distributed unstructured polyhedral mesh, the synchronization of the degrees of freedom, and the connection to scientific libraries including the partitioner METIS, the visualization tool PARAVIEW, and the parallel linear solver library PETSc. The parallel efficiency of this first version of the ComPASS code has been validated on a toy parabolic problem using the Vertex Approximate Gradient finite volume spacial discretization with both cell and vertex degrees of freedom, combined with an Euler implicit time integration
Report on the First Detection of Pectenotoxin-2, Spirolide-A and Their Derivatives in French Shellfish
In the context of the French Phytoplankton and Phycotoxins Monitoring Network (REPHY) programme, shellfish samples were harvested from different locations where harmful algae blooms were known to have occurred. For all shellfish samples found positive by the mouse bioassay for diarrhetic shellfish poisoning (DSP) toxins, liquid chromatography (LC) coupled with mass spectrometry (MS) was used to search for the following lipophilic toxins: okadaic acid (OA), dinophysistoxins (DTXs), pectenotoxins (PTXs), azaspiracids (AZAs), yessotoxins (YTXs), spirolides (SPXs) and gymnodimines (GYMs). In order to investigate the presence of acyl-OAs and/or acyl-DTX-1,-2 (DTX-3), alkaline hydrolysis was performed on all samples, and LC/MS analyses were carried out on the samples before and after hydrolysis. The results revealed different lipophilic toxin profiles as a function of the shellfish sampling location. The primary finding was that all of the samples contained OA and acyl-OA. In addition, other lipophilic toxins were found in shellfish samples: DTX-2, acyl-DTX-2 and SPXs (SPX-A, SPX-desMeC) on the Atlantic coast (Southern Brittany, Arcachon), and pectenotoxins (PTX-2, PTX-2-seco-acid and 7-epi-PTX-2-seco-acid) on the Mediterranean coast (Thau lagoon, the island of Corsica). This paper reports on the first detection of PTX-2, SPX-A and their derivatives in French shellfish
Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum.
In most organisms, the primary function of homologous recombination (HR) is to allow genome protection by the faithful repair of DNA double-strand breaks. The vital step of HR is the search for sequence homology, mediated by the RAD51 recombinase, which is stimulated further by proteins mediators such as the tumor suppressor BRCA2. The biochemical interplay between RAD51 and BRCA2 is unknown in Leishmania or Trypanosoma. Here we show that the Leishmania infantum BRCA2 protein possesses several critical features important for the regulation of DNA recombination at the genetic and biochemical level. A BRCA2 null mutant, generated by gene disruption, displayed genomic instability and gene-targeting defects. Furthermore, cytological studies show that LiRAD51 can no longer localize to the nucleus in this mutant. The Leishmania RAD51 and BRCA2 interact together and the purified proteins bind single-strand DNA. Remarkably, LiBRCA2 is a recombination mediator that stimulates the invasion of a resected DNA double-strand break in an undamaged template by LiRAD51 to form a D-loop structure. Collectively, our data show that LiBRCA2 and LiRAD51 promote HR at the genetic and biochemical level in L. infantum, the causative agent of visceral leishmaniasis
A Hardware and Software Platform for Aerial Object Localization
To date, there are little reliable data on the position, velocity and
acceleration characteristics of Unidentified Aerial Phenomena (UAP). The dual
hardware and software system described in this document provides a means to
address this gap. We describe a weatherized multi-camera system which can
capture images in the visible, infrared and near infrared wavelengths. We then
describe the software we will use to calibrate the cameras and to robustly
localize objects-of-interest in three dimensions. We show how object
localizations captured over time will be used to compute the velocity and
acceleration of airborne objects
Temporal dynamics of motion integration for the initiation of tracking eye movements at ultra-short latencies
Développement d'un processus coopératif de traitement d'images ultrasonores pour le référencement géométrique de structures osseuses en chirurgie orthopédique
La radiologie est actuellement la modalité d'imagerie la plus utilisée en chirurgie orthopédique, que ce soit en planification opératoire, en contrôle per-opératoire ou pour le suivi du patient. Un de ses inconvénients est de ne pas permettre un référencement géométrique des objets représentés. Il est donc impossible tout au long du processus chirurgical orthopédique, de mesurer précisément les modifications de géométrie des structures osseuses. En salle d'opération les instruments chirurgicaux sont référencés spatialement et permettent par palpations de points de référence une identification géométrique des structures osseuses. Ceci est limité au contexte chirurgical car ces palpations requièrent des incisions. Dans cette thèse, nous proposons d'introduire en chirurgie orthopédique une nouvelle approche fondée sur l'utilisation d'un capteur d'images ultrasonores dont le positionnement spatial est connu. Nous présentons une méthode d'analyse d'images ultrasonores qui aboutit à la détection des points de référence dans un contexte non chirurgical. Cet apport est fondamental car il introduit une continuité dans le contrôle précis de la géométrie des structures osseuses tout au long du processus chirurgical orthopédique de la planification opératoire jusqu'au suivi du patient. Pour déterminer la position des points de référence sur les images ultrasonores osseuses nous sommes passés par une étape intermédiaire consistant en la détection de l'interface osseuse par des approches fondées sur des modèles de contours. Devant la difficulté du problème lié à la très faible qualité des images ultrasonores osseuses, nous nous sommes orientés vers une approche coopérative innovante. Dès que la sonde est positionnée sur le patient, le système affiche en temps réel le contour détecté et le clinicien peut, par un mouvement continu de la sonde, faire converger le système vers une solution optimale au regard de son expertise et des propriétés images. La validation de nos algorithmes s'est tout d'abord effectuée en mode non coopératif sur une base de données contenant 651 images ultrasonores. Le meilleur algorithme fondé sur la recherche d'un chemin optimal parmi un ensemble de points de contours candidats a été validé en mode coopératif sur un prototype appelé PhysioPilot dédié à la mesure de paramètres physiologiques dans un contexte non chirurgicalX-rays remain the preferred imaging modality for orthopedic surgery for surgical planning, intra-operative control or patient follow-up. Nevertheless, it does not allow anatomical bone structures referencing. It is then impossible to control geometrical modifications of bone structures during the surgical process. However, surgical tools are referenced in the operating-room space and allow the surgeon to define anatomical structures geometrically by defining landmark positions. This process is only allowed during surgical procedures because it requires to do cuts on the patient. In this work, we propose a new approach using an ultrasound probe that is referenced in the operating-room space. We present an image processing algorithm to extract anatomical landmark position in a surgical context. It is a crucial improvement because it allows a complete patient follow-up from pre-operative planning to post-operative consults. To determine anatomical landmark positions on ultrasound images we added an intermediate step to extract the bone/soft tissues interface via several segmentation methods as active contours. Due to the low quality of ultrasound images we decided to design a innovative cooperative process. As the surgeon positions the ultrasound probe on the patient, the bone interface appears on the system screen in real time. Then the clinician can help the segmentation result to converge to the final solution by a soft movement of the probe. The validation of our work was performed on a database of 651 ultrasound images, in a non-cooperative way. The best algorithm that extracts the bone interface by defining the optimal path in a graph of potential candidates was validated with a cooperative protocol on a prototype called PhysioPilot, in order to perform physiological measurements in a non-surgical contextPARIS-EST-Université (770839901) / SudocSudocFranceF
Manifestations de la sécheresse en Afrique de l'Ouest non sahélienne : cas de la Côte d'Ivoire, du Togo et du Bénin
La sécheresse qui sévit depuis une vingtaine d'années dans les régions sahéliennes d'Afrique de l'Ouest semble avoir des manifestations également plus au sud dans les pays riverains du golfe de Guinée. Une double analyse, ponctuelle et spatialisée, concernant les précipitations annuelles de la Côte d'Ivoire, du Togo et du Bénin permet de mettre ce fait en évidence. Les séries chronologiques d'indices pluviométriques confirment la chute brutale de la pluviométrie à la fin des années 60. La représentation cartographique des résultats montre le net glissement des courbes isohyètes vers le sud et permet de prendre en compte la dimension régionale du phénomène. (Résumé d'auteur
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