123 research outputs found
Open Multi-Access Network Platform with Dynamic Task Offloading and Intelligent Resource Monitoring
We constructed an open multi-access network platform using open-source
hardware and software. The open multi-access network platform is characterized
by the flexible utilization of network functions, integral management and
control of wired and wireless access networks, zero-touch provisioning,
intelligent resource monitoring, and dynamic task offloading. We also propose
an application-driven dynamic task offloading that utilizes intelligent
resource monitoring to ensure effective task processing in edge and cloud
servers. For this purpose, we developed a mobile application and server
applications for the open multi-access network platform. To investigate the
feasibility and availability of our developed platform, we experimentally and
analytically evaluated the effectiveness of application-driven dynamic task
offloading and intelligent resource monitoring. The experimental results
demonstrated that application-driven dynamic task offloading could reduce
real-time task response time and traffic over metro and core networks
Conversion of MO programs to True BASIC
Programs of overlap integrals and extended Huckcl MO can be coded using external subroutines by True BASIC without using line numbers and go to statements. The use of MAT statements are found to be effective in expressing matrix Operations
Construction and Characterization of a PGN_0297 Mutant of Porphyromonas gingivalis: Evidence of the Contribution of PGN_0297 to Gingipain Activity
The periodontal pathogen Porphyromonas gingivalis shows colonial pigmentation on blood agar and produces gingipains (Kgp, RgpA, and RgpB), cysteine proteases involved in an organism’s virulence and pigmentation. We showed previously that deletion of the PGN_0300 gene abolished the pigmentation activity and reduced the proteolytic activity of gingipains. The role of the PGN_0297 gene, which consists of an operon with the PGN_0300 gene, is unclear. Herein we examined the effect of PGN_0297 gene deletion on the pigmentation and proteolytic activities and transcriptional levels of gingipains. A PGN_0297 gene deletion mutant (ΔPGN_0297) did not exhibit the pigmentation. The proteolytic activity of the gingipains was decreased in the culture supernatant and on the cell surface of ΔPGN_0297. The mutant ΔPGN_0297 failed to attenuate Akt phosphorylation at Thr308 and Ser473, but both phosphorylations were attenuated in the wild-type and its complementation strain. The deletion of PGN_0297 gene did not substantially affect the transcriptional levels of the gingipain genes kgp, rgpA, and rgpB. Taken together, these results indicate that PGN_0297 is closely involved in the secretion and maturation of gingipains
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