Preliminary study: Comparison of antioxidant activity of cannabidiol (CBD) and α-tocopherol added to refined olive and sunflower oils

This study evaluates the antioxidant activity of cannabidiol (CBD), added to model systems of refined olive (ROO) and sunflower (SO) oils, by measuring the peroxide value, oxidative stability index (OSI), electron spin resonance (ESR) forced oxidation, and DPPH• assays. Free acidity, a parameter of hydrolytic rancidity, was also examined. CBD was compared using the same analytical scheme with α-tocopherol. CBD, compared to α-tocopherol, showed a higher scavenging capacity, measured by DPPH• assay, but not better oxidative stability (OSI) of the oily systems considered. In particular, α-tocopherol (0.5%) showed an antioxidant activity only in SO, registered by an increase of more than 30% of the OSI (from 4.15 ± 0.07 to 6.28 ± 0.11 h). By ESR-forced oxidation assay, the concentration of free radicals (μM) in ROO decreased from 83.33 ± 4.56 to 11.23 ± 0.28 and in SO from 19.21 ± 1.39 to 6.90 ± 0.53 by adding 0.5% α-tocopherol. On the contrary, the addition of 0.5% CBD caused a worsening of the oxidative stability of ROO (from 23.58 ± 0.32 to 17.28 ± 0.18 h) and SO (from 4.93 ± 0.04 to 3.98 ± 0.04 h). Furthermore, 0.5% of CBD did not lower dramatically the concentration of free radicals (μM) as for α-tocopherol, which passed from 76.94 ± 9.04 to 72.25 ± 4.13 in ROO and from 17.91 ± 0.95 to 16.84 ± 0.25 in SO

Composition and Epigenetic Markers of Heterochromatin in the Aphid Aphis nerii (Hemiptera: Aphididae).

A detailed karyotype analysis of the oleander aphid Aphis nerii focusing on the distribution, molecular composition and epigenetic modifications of heterochromatin was done in order to better understand the structure and evolution of holocentric/holokinetic chromosomes in aphids. The female karyotype (2n = 8) consisted of 3 pairs of autosomes and a pair of X chromosomes that were the longest elements in the karyotype and carried a single, terminally located nucleolar organizer region. Males showed 2n = 7 chromosomes due to the presence of a single X chromosome. Heterochromatin was located in the X chromosomes only and consisted of 4 satellite DNAs that have been identified. A. nerii constitutive heterochromatin was enriched in mono-, di- and tri-methylated H3 histones and HP1 proteins but, interestingly, it lacked DNA methylation that was widespread in euchromatic chromosomal regions. These results suggest that aphid heterochromatin is assembled and condensed without any involvement of DNA methylation

Fragmentation of very high energy heavy ions

A stack of CR39 (C12H18O7)n nuclear track detectors with a Cu target was exposed to a 158 A GeV lead ion beam at the CERN-SPS, in order to study the fragmentation properties of lead nuclei. Measurements of the total, break-up and pick-up charge-changing cross sections of ultrarelativistic Pb ions on Cu and CR39 targets are presented and discussed.Comment: 4 pages, 3 EPS figures included with epsf, uses article.sty Talk presented by M. Giorgini at the Int. Conf. on Structure of the Nucleus at the Dawn of the Century, Bologna (Italy), May 29-June 3, 200

Fragmentation cross sections of Fe^{26+}, Si^{14+} and C^{6+} ions of 0.3-10 A GeV on CR39, polyethylene and aluminum targets

New measurements of the total and partial fragmentation cross sections in the energy range 0.3-10 A GeV of Fe^{26+}, Si^{14+} and C^{6+} beams on polyethylene, CR39 and aluminum targets are presented. The exposures were made at Brookhaven National Laboratory (BNL), USA, and Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The CR39 nuclear track detectors were used to identify the incident and survived beams and their fragments. The total fragmentation cross sections for all targets are almost energy independent while they depend on the target mass. The measured partial fragmentation cross sections are also discussed.Comment: 4 pages, 5 eps figures. Talk given at the 24th International Conference on Nuclear Tracks in Solids, Bologna, Italy, 1-5 September 200

Prediction of DC-Link Voltage Switching Ripple in Three-Phase Four-Leg PWM Inverters

This paper presents a thorough prediction of DC-link voltage switching ripples in the three-phase four-leg inverters operating in balanced and unbalanced working conditions. The unbalanced modes examined here employ the highest degree of AC current imbalance while still preserving three-phase operation. This behavior can be found in many grid-connected or standalone grid-forming three-phase converters that supply "heavy" single-phase loads, comprising a recent trend in smart-grid, smart electric vehicle (EV)-charging applications. In this sense, for instance, the smart EV chargers might be employed in conditions when different power is drawn/injected from/to the grid, providing power conditioning services to the latter. The analysis of three-phase four-leg inverters is then extended to single-phase operations typical of home-charging or vehicle-to-home (V2H) applications. Their performances in terms of DC-link voltage switching ripple are demonstrated. Two of the most common carrier-based PWM modulation techniques are employed to drive the three-phase inverter-namely, sinusoidal PWM and centered PWM (carrier-based analogy of the space vector modulation). The derived mathematical expressions of peak-to-peak and RMS values of DC-link voltage switching ripple for balanced and unbalanced conditions are handy for designing the associated DC-link capacitor and estimating the overall efficiency of the converter. Extensive numerical simulations and experimental tests have been performed to validate the presented analytical developments

A Novel MIMO Control for Interleaved Buck Converters in EV DC Fast Charging Applications

This brief proposes a new multiple input multiple output (MIMO) control for off-board electric vehicle (EV) dc fast chargers. The proposed feedback matrix design avoids multiple tuning of controllers in multiple and interconnected loops while improving the performance of interleaved dc buck converters over classical PI/PID controls. The innovative features of the presented strategy are the reference current monotonic tracking from any initial state of charge with an arbitrarily fast settling time and the fast compensation of both load variations and imbalances among the legs. Numerical results validate the performance improvements of the proposed discrete-time MIMO algorithm for interleaved buck converters over classical PI/PID controls. Full-scale hardware-in-the-loop (HIL) and scaled-down prototype experimental results prove the feasibility and effectiveness of the proposal

AC Current Ripple in Three-Phase Four-Leg PWM Converters with Neutral Line Inductor

This paper presents a comprehensive study of peak-to-peak and root-mean-square (RMS) values of AC current ripples with balanced and unbalanced fundamental currents in a generic case of three-phase four-leg converters with uncoupled AC interface inductors present in all three phases and in neutral. The AC current ripple characteristics were determined for both phase and neutral currents, considering the sinusoidal pulse-width modulation (SPWM) method. The derived expressions are simple, effective, and ready for accurate AC current ripple calculations in three- or four-leg converters. This is particularly handy in the converter design process, since there is no need for heavy numerical simulations to determine an optimal set of design parameters, such as switching frequency and line inductances, based on the grid code or load restrictions in terms of AC current ripple. Particular attention has been paid to the performance comparison between the conventional three-phase three-leg converter and its four-leg counterpart, with distinct line inductance values in the neutral wire. In addition to that, a design example was performed to demonstrate the power of the derived equations. Numerical simulations and extensive experimental tests were thoroughly verified the analytical developments

Fragmentation studies of high energy ions using CR39 nuclear track detectors

We report on the measurements of the total charge changing fragmentation cross sections in high-energy nucleus-nucleus collisions using Fe, Si and Pb incident ions. Several stacks of CR39 nuclear track detectors with different target combinations were exposed at normal incidence to high energy accelerator beams to integrated densities of about 2000 ions/cm^2. The nuclear track detector foils were chemically etched, and ion tracks were measured using an automatic image analyzer system. The cross section determination is based on the charge identification of beam ions and their fragments and on the reconstruction of their path through the stacks.Comment: 5 pages, 4 EPS figures. Corrected Eq. 3 and Table 1. Presented at the 10th Inter. Symp. Radiat. Phys., Coimbra, Portugal, 17-22 Sept. 200