Clinical study of a multivitamin and polymineral complex associated with Panax ginseng extract (Natus Gerin®)

This study aimed to stablish the efficacy of a multivitamin and polyminerals supplemented with Panax ginseng extract (Natus Gerin®) on patients subjected to common physical or mental stress. Patients were randomly divided in two groups and underwent a thorough clinical examination. Group A received Natus Gerin® capsules and B placebo capsules. Two capsules were taken daily during meals during four weeks. Mood and physical activity were evaluated through a questionnaire assessing quality of life. From the 176 patients enrolled, 17 were excluded due to voluntary withdrawal, 81 completed the study in group A and 78 in group B. The treatment with Natus Gerin® increased the quality of life when compared to placebo. After 15 and 30 days, group A showed a significant increase in average scoring score from 1.78 to 3.78, and finally 5.32 points. The study has shown that the daily use of Natus Gerin® can be effective in improving quality of life in patients suffering from physical and mental stressColegio de Farmacéuticos de la Provincia de Buenos Aire

Emprego e Mecanização na Colheita da Cana-de-Açúcar: diferenças regionais

A major concern about the mechanized of cane sugar production are the direct and indirect impacts on employment generation. To study these impacts were: a)made an inter-regional input-output model , using the matrix for the Brazilian economy in 1997, considering the five macro regions, emphasizing the Cane Sugar, Alcohol and Sugar sectors b) estimated the level of employment for the sectors of the model, considering the level of qualification of labor, that is, by years of study (less than 1 year between 1 and 3 years, 4 and 7 years 8 and 10, 11 and 14, and finally, over 15 years), c) built two sets for the process of machining and to changes in crop productivity. The results showed that the 510,651 people who were working in the sugarcane harvest in 1997,depending on the scenario that was considered, the total workforce will be reduced between 243,211 and 273,276 people, mainly those with low skill levels in the Northeast and Southeast . This also has an indirect impact on the generation of employment, which is estimated by the inter-regional input-output model built for the study

Emprego e Mecanização na Colheita da Cana-de-Açúcar: diferenças regionais

A major concern about the mechanized of cane sugar production are the direct and indirect impacts on employment generation. To study these impacts were: a)made an inter-regional input-output model , using the matrix for the Brazilian economy in 1997, considering the five macro regions, emphasizing the Cane Sugar, Alcohol and Sugar sectors b) estimated the level of employment for the sectors of the model, considering the level of qualification of labor, that is, by years of study (less than 1 year between 1 and 3 years, 4 and 7 years 8 and 10, 11 and 14, and finally, over 15 years), c) built two sets for the process of machining and to changes in crop productivity. The results showed that the 510,651 people who were working in the sugarcane harvest in 1997,depending on the scenario that was considered, the total workforce will be reduced between 243,211 and 273,276 people, mainly those with low skill levels in the Northeast and Southeast . This also has an indirect impact on the generation of employment, which is estimated by the inter-regional input-output model built for the study

Mechanization process of the sugar cane harvest and its direct and indirect impact over the employment in Brazil and in its 5 macro regions

One of the main concerns about the mechanization process of the sugar cane harvest is its direct and indirect impact over the employment. To study such an impact, it was: a) constructed an interregional input-output model, for the Brazilian economy for 1997, at the level of its 5 macro regions, with specific details for the sugar cane, alcohol, and sugar sectors; b) estimated the employment level, for the sectors in the model, by the qualification level of the workforce, i.e., by years of study (less than 1 year, 1 to 3 years, 4 to 7 years, 8 to 10 years, 11 to 14 years, and greater than 15 years); c) construct 3 possible scenarios for the mechanization process. The results are rather stressing, from the estimated 510,651 people working in the sugar cane harvest in 1997, one has that, depending on the scenario being considered, the total workforce will be reduced somewhere between 243,211 to 316,288 people, mainly in the lower qualification levels and in the Northeast and Southeast regions. This also has an impact over the employment generate indirectly, which is estimated through the use of the interregional input-output model constructed

Mechanization process of the sugar cane harvest and its direct and indirect impact over the employment in Brazil and in its 5 macro regions

One of the main concerns about the mechanization process of the sugar cane harvest is its direct and indirect impact over the employment. To study such an impact, it was: a) constructed an interregional input-output model, for the Brazilian economy for 1997, at the level of its 5 macro regions, with specific details for the sugar cane, alcohol, and sugar sectors; b) estimated the employment level, for the sectors in the model, by the qualification level of the workforce, i.e., by years of study (less than 1 year, 1 to 3 years, 4 to 7 years, 8 to 10 years, 11 to 14 years, and greater than 15 years); c) construct 3 possible scenarios for the mechanization process. The results are rather stressing, from the estimated 510,651 people working in the sugar cane harvest in 1997, one has that, depending on the scenario being considered, the total workforce will be reduced somewhere between 243,211 to 316,288 people, mainly in the lower qualification levels and in the Northeast and Southeast regions. This also has an impact over the employment generate indirectly, which is estimated through the use of the interregional input-output model constructed

Clinical study of a multivitamin and polymineral complex associated with Panax ginseng extract (Natus Gerin®)

This study aimed to stablish the efficacy of a multivitamin and polyminerals supplemented with Panax ginseng extract (Natus Gerin®) on patients subjected to common physical or mental stress. Patients were randomly divided in two groups and underwent a thorough clinical examination. Group A received Natus Gerin® capsules and B placebo capsules. Two capsules were taken daily during meals during four weeks. Mood and physical activity were evaluated through a questionnaire assessing quality of life. From the 176 patients enrolled, 17 were excluded due to voluntary withdrawal, 81 completed the study in group A and 78 in group B. The treatment with Natus Gerin® increased the quality of life when compared to placebo. After 15 and 30 days, group A showed a significant increase in average scoring score from 1.78 to 3.78, and finally 5.32 points. The study has shown that the daily use of Natus Gerin® can be effective in improving quality of life in patients suffering from physical and mental stressColegio de Farmacéuticos de la Provincia de Buenos Aire

Karyotypic conservatism in samples of Characidium cf. zebra (Teleostei, Characiformes, Crenuchidae): Physical mapping of ribosomal genes and natural triploidy

Basic and molecular cytogenetic analyses were performed in specimens of Characidium cf. zebra from five collection sites located throughout the Tietê, Paranapanema and Paraguay river basins. The diploid number in specimens from all samples was 2n = 50 with a karyotype composed of 32 metacentric and 18 submetacentric chromosomes in both males and females. Constitutive heterochromatin was present at the centromeric regions of all chromosomes and pair 23, had additional interstitial heterochromatic blocks on its long arms. The nucleolar organizer regions (NORs) were located on the long arms of pair 23, while the 5S rDNA sites were detected in different chromosomes among the studied samples. One specimen from the Alambari river was a natural triploid and had two extra chromosomes, resulting in 2n = 77. The remarkable karyotypic similarity among the specimens of C. cf. zebra suggests a close evolutionary relationship. On the other hand, the distinct patterns of 5S rDNA distribution may be the result of gene flow constraints during their evolutionary history

Phase II clinical study of an association for the treatment of interstitial cystitis (Cystex?).

Painful bladder syndrome associated with interstitial cystitis (PBS/IC) is a clinical condition characterized pelvic pain, urinary urgency, and urinary frequency. In this study, 22 patients were assigned to make two visits over a three weeks period. The patients were randomly, double-blinded assigned in two groups. The first group received Cystex? capsules. The second group received placebo capsules. Two capsules were taken three times a day away from meals. The change from baseline in the O?Leary-Sant IC symptom and problem index was the primary outcome parameter. Changes in functional bladder capacity and intensity of pain and urgency have been chosen as secondary outcome parameters. Mood as well as physical and sexual activity were rated by 10 questions on a scale 0 to 6. The ratings were analyzed and the average for each patient in both groups Cystex? and placebo was determined as the quality of life index. For the primary outcome there was a statistically significant difference between the groups. Mean symptom score-sum decreased from 28.4 to 20.5 in the Cystex? group compared with 29.5 to 26.8 in the placebo group (p<0.05). For the secondary end points, pain and urgency intensity improved statistically significantly in the Cystex? group compared with the placebo group (p<0.05). The frequency and functional bladder capacity improved to greater degree in the Cystex? group. The differences were statistically significant for comparison of frequency (p<0.05) and not for functional bladder capacity (p>0.05). In our study, Cystex? enhanced quality of life over the placebo showing a statistically significant. This trial have shown that the efficacy and safety of therapy with Cystex? in the treatment of interstitial cystitis and is an alternative for patients suffering from this pathology. Therefore, it can be concluded that the composition of Cystex?, increased the quality of life in treated patients