Cold spray deposition of WC-Co

Tese de mestrado integrado. Engenharia Metalúrgica e de Materiais. Universidade do Porto. Faculdade de Engenharia. 201

Pichia pastoris (Komagataella phaffii) as a Cost-Effective Tool for Vaccine Production for Low- and Middle-Income Countries (LMICs)

Vaccination is of paramount importance to global health. With the advent of the more recent pandemics, the urgency to expand the range has become even more evident. However, the potential limited availability and affordability of vaccines to resource low‐ and middle‐income countries has created a need for solutions that will ensure cost‐effective vaccine production methods for these countries. Pichia pastoris (P. pastoris) (also known as Komagataella phaffii) is one of the most promising candidates for expression of heterologous proteins in vaccines development. It combines the speed and ease of highly efficient prokaryotic platforms with some key capabilities of mammalian systems, potentially reducing manufacturing costs. This review will examine the latest developments in P. pastoris from cell engineering and design to industrial production systems with focus on vaccine development and with reference to specific key case studies

Varta ag seizes opportunity in segment set to dominate the battery market

This paper accesses VARTA AG as a potential PE House target. VARTAAG is a company present in some of the highest growing segments of the battery market–and has the technological and production capacity that allowing it to keep track with market growth. More over, VARTA has the technological capacity to tapinanun explored segment, by the company, of the battery market–the hight growth segment of the Electric Vehicle(EV) Batteries. This Investment Co capable of pursuing of interesting value creation strategies, EV Battery Facility and Materials Recycling facility, that make VARTA an interesting target fo ra Leveraged Buy Out(LBO)

Digital Transformation in IT Consulting

Internship Report presented as the partial requirement for obtaining a Master's degree in Information Management, specialization in Knowledge Management and Business IntelligenceAs IT Consulting market revenue increases year after year, more and more digital transformation projects are being sold. Yet, the deep change IT consultants sell to their clients in this type of projects, which translates into the digitalisation of practices accompanied by a change in mentalities, is not usually the reality that we find in their same consultancy firms. For Creative Management, the company that hosted the internship, the problem recurs: there is a general desire of evolving into a digital company, with some disconnected digital tools already implemented but without planning or coordination. Literature shows that a Digital Transformations requires several premises to develop into a successful project such as the definition of a plan, the knowledge and support of leaders, investment, etc. My project, within the internship, aimed to address Digital Transformation at Creative Management by coordinating an internal digital strategy that materialized in new technological tools. The key takeaway is the fact that an IT Consulting firm is probably better prepared for this type of change than non-IT consultancies

Impacto de alterações da temperatura sobre a severidade do míldio da videira.

Diante dos cenários climáticos futuros, a temperatura do ar sofrerá aumentos, interferindo na distribuição geográfica e temporal de doenças. O míldio, causado pelo fungo Plasmopara viticola, é uma das principais doenças que ocorre na videira. O desenvolvimento deste patógeno pode ser influenciado por vários fatores ambientais, entre eles, a temperatura. O objetivo deste trabalho foi avaliar o impacto do aumento da temperatura na severidade do míldio da videira nas cultivares Crimson, Thompson e Alicante. Para a avaliação, mudas com 4-6 folhas foram inoculadas com uma suspensão de esporos na concentração de 105 esporos/mL + Tween 20 a 0,01%, por meio de pulverização. Após a inoculação, as mudas foram submetidas às temperaturas de 26, 28, 29.1, 30.4 e 31.8 oC, por 24 horas. Posteriormente, as mudas foram mantidas a temperatura de 26 oC, fotoperíodo 12 horas até a avaliação dos resultados. Foi avaliada a porcentagem da área foliar doente, por meio de escala diagramática e o período latente, determinado pelo número de dias entre a inoculação e a produção de esporos. O aumento da temperatura interferiu na infecção do míldio da videira, diminuindo a severidade da doença e aumentando o período latente

Solid wood treated by plasma jet.

Editado por Luiz Henrique Capparelli Mattoso, Alcides Leão e Elisabete Frollini