A MOF-based social web services description metamodel

© Copyright 2016 by SCITEPRESS - Science and Technology Publications, Lda. All rights reserved. To promote and support the development and use of social Web services by the IT community on the Web, both social Web service-based applications and their support platforms should evolve independently from each other while sharing a common model that represents the characteristics of these social Web services. To achieve this duality, this paper proposes a model-driven approach. First, the approach identifies a social Web service\u27s properties. Then a Meta-Object-Facility (MOF)-based social Web services description metamodel is developed. Finally, a prototype illustrates how the MOF-based metamodel is used

On Modelling and Analyzing Composite Resources’ Consumption Cycles using Time Petri-Nets

ICT community cornerstones (IoT in particular) gain competitive advantage from using physical resources. This paper adopts Time Petri-Nets (TPNs) to model and analyze the consumption cycles of composite resources. These resources consist of primitive, and even other composite, resources that are associated with consumption properties and could be subject to disruptions. These properties are specialized into unlimited, shareable, limited, limited-but-renewable, and non-shareable, and could impact the availability of resources. This impact becomes a concern when disruptions suspend ongoing consumption cycles to make room for the unplanned consumptions. Resuming the suspended consumption cycles depends on the resources’ consumption properties. To ensure correct modeling and analysis of consumption cycles, whether disrupted or not, TPNs are adopted to verify that composite resources are reachable, bound, fair, and live

Synthèse et propriétés complexantes de multi-calixarènes

Dans une première partie, nous avons synthétisé des multi-calixarènes contenant de une à six unités calixaréniques reliées entre elles par des espaceurs de différentes natures. Dans une deuxième partie, nous avons choisi certains des dérivés précédemment synthétisés pour construire des fluoroionophores à fluorophore unique (pyrène) ou fluorophores mixtes (pyrène et rhodamine) à base de calixarènes. Tous les dérivés ainsi synthétisés ont été caractérisés par 1H-RMN, 13C-RMN, spectrométrie de masse maldi-tof, microanalyse et dans certains cas, diffraction des rayons X. Dans une dernière partie, nous avons étudiés les propriétés complexantes et extractantes de six des ligands synthétisés auparavant, vis-à-vis de sept cations de lanthanides trivalents (La, Pr, Nd, Eu, Gd, Er et Yb) et certains métaux de transition (Co, Cu, Zn, Cd) et Al. En fin de thèse nous présentons l étude de la complexation par fluorescence. La présence d un transfert de type FRET est montrée.In a first part, we have synthesized multi-calixarenes containing one to six calixarenic units connected by various spacers. In a second part, we have chosen some derivatives previously synthesized to build based-calixarenes fluoroionophores with one type of fluorophore (pyrene) or mixed fluorophores (pyrene and rhodamine). All the derivatives thus synthesized were characterized by 1H-NMR, 13C-NMR, mass spectrometry MALDI-TOF, microanalysis and in certain cases, X-rays diffraction. In a last part, we have studied the chelating and extracting properties of six of the ligands synthesized before, with respect to seven cations of trivalent lanthanides (La, Pr, Nd, Eu, Gd, Er and Yb and some transition metals (Co, Cu, Zn, Cd) and Al. At the end of the thesis we have presented a study of the complexation by fluorescence. The presence of a transfer of the FRET type is shown.STRASBOURG-Sc. et Techniques (674822102) / SudocSudocFranceF

Terahertz imaging and spectroscopy for security and defense applications

International audienc

A Privacy-Sensitive, Situation-Aware Description Model for IoT

International audienceThis chapter discusses the impact of the ``calm'' invasion of the Internet-of-Things~(IoT) on people's private lives to the extent that the expected benefits of IoT have become concerns to people. To mitigate this impact, this chapter presents a Model-Driven~Architecture (MDA)-based approach for injecting privacy concerns into thing specifications so, that, things would become alert to these concerns and, hence, would act accordingly. Being alert should mean a better assessment of what needs to be done, when, and where prior to violating any privacy policies. For illustration and demonstration purposes, WoT Thing Description~(WoT TD) is adopted as an example of W3C thing specification. To make things aware of situation-related privacy concerns, the approach presented in this chapter defines SituationPrivacy metamodel, merges SituationPrivacy and WoT TD metamodels into SituationPrivacyWoTTD metamodel, and, finally, generates SituationPrivacyWoTTD model using an in-house case tool. Privacy concerns and the MDA approach that addresses these concerns are illustrated and demonstrated with a case study about a care center for elderly people

High prevalence of gut microbiota colonization with broad-spectrum cephalosporin resistant Enterobacteriaceae in a Tunisian intensive care unit

Healthcare-associated infections due to cefotaxime-resistant Enterobacteriaceae (CRE) have become a major public health threat, especially in intensive care units (ICUs). Often acquired nosocomially, CRE can be introduced initially by patients at admission. This study aimed to determine the prevalence and genetic characteristics of CRE-intestinal carriage in ICU patients, to evaluate the rate of acquisition of these organisms during hospitalization, and to explore some of the associated risk factors for both carriage and acquisition.Between December 2014 and February 2015, the 63 patients admitted in the ICU of Charles Nicolle hospital were screened for rectal CRE colonization at admission and once weekly thereafter to identify acquisition. CRE fecal carriage rate was 20.63% (13/63) at admission and the acquisition rate was 42.85% (15/35). Overall, 35 CRE isolates were collected from 28 patients (25 Klebsiella pneumoniae, 7 Escherichia coli and 3 Enterobacter cloacae strains). Seven patients were simultaneously colonized with 2 CRE isolates. CTX-M-15 was detected in most of the CRE isolates (30/35, 88.23%).Three strains co-produced CMY-4 and 22 strains were carbapenem-resistant and co-produced a carbapenemase OXA-48 (n=13) or NDM-1 (n=6). All isolates were multidrug resistant. Molecular typing of K. pneumoniae strains, revealed 8 Pulsed field gel electrophoresis (PFGE) patterns and 4 sequence types (ST) ST101, ST147, ST429 and ST336. However, E. coli isolates were genetically unrelated and belonged to A (n=2), B1 (n=2) and B2 (n=3) phylogenetic groups and to ST131 (2 strains), ST572 (2 strains), ST615 (one strain) and ST617 (one strain). Five colonized patients were infected by CRE (4 with the same strain identified from their rectal swab and 1 with a different strain). Whether imported or acquired during the stay in the ICU, colonization by CRE is a major risk factor for the occurrence of serious nosocomial infections. Their systematic screening in fecal carriage is mandatory to prevent the spread of these multidrug resistant bacteria

Meningococcal Disease In The Middle East And Africa: Findings And Updates From The Global Meningococcal Initiative

The Global Meningococcal Initiative (GMI) has recently considered current issues in Middle Eastern and African countries, and produced two recommendations: (i) that vaccination of attendees should be considered for some types of mass-gathering events, as some countries mandate for the Hajj, and (ii) vaccination of people with human immunodeficiency virus should be used routinely, because of increased meningococcal disease (MD) risk. Differences exist between Middle Eastern and African countries regarding case and syndrome definitions, surveillance, and epidemiologic data gaps. Sentinel surveillance provides an overview of trends and prevalence of different capsular groups supporting vaccine selection and planning, whereas cost-effectiveness decisions require comprehensive disease burden data, ideally counting every case. Surveillance data showed importance of serogroup B MD in North Africa and serogroup W expansion in Turkey and South Africa. Success of MenAfriVac (R) in the African "meningitis belt" was reviewed; the GMI believes similar benefits may follow development of a low-cost meningococcal pentavalent vaccine, currently in phase 1 clinical trial, by 2022. The importance of carriage and herd protection for controlling invasive MD and the importance of advocacy and awareness campaigns were also highlighted. (C) 2017 The Authors. Published by Elsevier Ltd on behalf of The British Infection Association.WoSScopu

A regionally based precision medicine implementation initiative in North Africa:The PerMediNA consortium

International audiencePrecision Medicine is being increasingly used in the developed world to improve health care. While several Precision Medicine (PM) initiatives have been launched worldwide, their implementations have proven to be more challenging particularly in low- and middle-income countries. To address this issue, the “Personalized Medicine in North Africa” initiative (PerMediNA) was launched in three North African countries namely Tunisia, Algeria and Morocco. PerMediNA is coordinated by Institut Pasteur de Tunis together with the French Ministry for Europe and Foreign Affairs, with the support of Institut Pasteur in France. The project is carried out along with Institut Pasteur d’Algérie and Institut Pasteur du Maroc in collaboration with national and international leading institutions in the field of PM including Institut Gustave Roussy in Paris. PerMediNA aims to assess the readiness level of PM implementation in North Africa, to strengthen PM infrastructure, to provide workforce training, to generate genomic data on North African populations, to implement cost effective, affordable and sustainable genetic testing for cancer patients and to inform policy makers on how to translate research knowledge into health products and services. Gender equity and involvement of young scientists in this implementation process are other key goals of the PerMediNA project.In this paper, we are describing PerMediNA as the first PM implementation initiative in North Africa. Such initiatives contribute significantly in shortening existing health disparities and inequities between developed and developing countries and accelerate access to innovative treatments for global health