15 research outputs found

    Effect of valerian capsules in patients with migraine attacks treated with sodium valproate: a randomized clinical trial

    Get PDF
    Background and aims: Nowadays so many preventive drugs for migraine with different effects are used all around the world. One of the plants that are used traditionally in the treatment of migraine is Valeriana officinalis. The present study was aimed to evaluate the effect of valerian capsule (350 mg, three times daily) on frequency, duration and intensity of migraine attacks. Method: The present study is a Randomized, single-blind clinical trial that is carried out on 84 female patients suffering from migraine headaches. The patients were randomly allocated to case (n=42) and control groups (n=42) and treated during three consecutive phases of 45 days. In the first phase, both groups received sodium valproate tablet, (200 mg, twice daily) and indomethacin capsule (25 mg, in attacks). In the second phase, valerian capsule (350 mg, three times daily) was added to other drugs of case group. Control group received placebo instead of valerian. Finally, in the third phase, both groups were treated the same as the first phase. And then the data obtained from the drug influence on pain intensity were analyzed based on Mann-Whitney and K2. Results: All 84 patients cooperated to the end of study. The results indicated that valerian capsule significantly reduced the frequency, duration and intensity of migraine attacks in a way that the mean of migraine attacks reduced from 6.2±2.3 to 2.2±1.2, the duration reduced from 17.0± 9.2 to 5.7±3.7 hours and intensity from 8.7±1.2 to 3.0±1.3. Conclusion: According to the remarkable effect of valerian capsule on the prevention of migraine attacks, it seems that it can be a potential alternative to common migraine medications

    The effect of heavy metal on Chlorella vulgaris, Scenedesmus obliquus and Anabaena flos-aquae

    Get PDF
    In this survey two species of chlorophyta (Chlorella vulgaris and Scenedesmus obliquus) and one species of blue-green algae (Anabaena flos- aquae) were exposed with heavy metal (zinc) under lab condition (temp. 25±2°C, light 3500±350 lux) for 96 hours. After this time, these species were counted with hemocytometer and based on probit analysis method and was determined ECIO, EC50 and EC90. Amount of EC50 for C. vulgaris, S. obliquus and A. flos-aquae were 0.134,0.047 and 0.093 mg/lit, respectively and this subject was distincted that S obliquus has more endurance than other species. Max value of zinc for these species (C. vulgaris, S. obiquus and A. flos-aquae ) were 0.0134, 0.0047 and 0.0093 mg/l respectively. Regression coefficient was 92-98 percent between concentration logarithm of zinc and decrease of these species density

    C‌o‌n‌t‌r‌o‌l‌l‌e‌d d‌e‌m‌o‌l‌i‌t‌i‌o‌n, c‌o‌l‌l‌a‌p‌s‌e c‌o‌m‌p‌u‌t‌e‌r s‌i‌m‌u‌l‌a‌t‌i‌o‌n, h‌i‌g‌h-r‌i‌s‌e b‌u‌i‌l‌d‌i‌n‌g‌s, p‌r‌o‌g‌r‌e‌s‌s‌i‌v‌e c‌o‌l‌l‌a‌p‌s‌e.

    No full text
    T‌h‌e p‌r‌e‌d‌i‌c‌t‌i‌o‌n o‌f t‌h‌e c‌o‌l‌l‌a‌p‌s‌e s‌t‌a‌g‌e‌s o‌f a s‌t‌r‌u‌c‌t‌u‌r‌e, c‌a‌u‌s‌e‌d b‌y s‌p‌e‌c‌i‌a‌l e‌x‌p‌l‌o‌s‌i‌v‌e‌s, u‌s‌e‌d f‌o‌r c‌o‌n‌t‌r‌o‌l‌l‌e‌d d‌e‌m‌o‌l‌i‌t‌i‌o‌n, o‌r u‌n‌d‌e‌r a‌n‌y e‌x‌t‌r‌e‌m‌e l‌o‌a‌d‌i‌n‌g‌s, s‌u‌c‌h a‌s b‌l‌a‌s‌t h‌a‌s b‌e‌e‌n o‌f i‌n‌t‌e‌r‌e‌s‌t t‌o d‌e‌s‌i‌g‌n‌e‌r‌s a‌n‌d s‌t‌r‌u‌c‌t‌u‌r‌a‌l e‌n‌g‌i‌n‌e‌e‌r‌s i‌n r‌e‌c‌e‌n‌t d‌e‌c‌a‌d‌e‌s. I‌n t‌h‌i‌s a‌r‌t‌i‌c‌l‌e, t‌h‌e c‌o‌l‌l‌a‌p‌s‌e s‌t‌a‌g‌e‌s o‌f h‌i‌g‌h r‌i‌s‌e R‌C b‌u‌i‌l‌d‌i‌n‌g‌s w‌i‌t‌h m‌o‌m‌e‌n‌t r‌e‌s‌i‌s‌t‌i‌n‌g f‌r‌a‌m‌e‌s, d‌u‌e t‌o r‌e‌m‌o‌v‌a‌l o‌f c‌e‌r‌t‌a‌i‌n m‌e‌m‌b‌e‌r‌s o‌f t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e, d‌e‌s‌t‌r‌o‌y‌e‌d i‌n‌t‌e‌n‌t‌i‌o‌n‌a‌l‌l‌y o‌r a‌c‌c‌i‌d‌e‌n‌t‌a‌l‌l‌y, h‌a‌s b‌e‌e‌n s‌i‌m‌u‌l‌a‌t‌e‌d b‌y t‌h‌e a‌i‌d o‌f a d‌e‌v‌e‌l‌o‌p‌e‌d c‌o‌m‌p‌u‌t‌e‌r p‌r‌o‌g‌r‌a‌m. T‌h‌e c‌o‌m‌p‌u‌t‌e‌r s‌o‌f‌t‌w‌a‌r‌e, t‌o s‌i‌m‌u‌l‌a‌t‌e t‌h‌e p‌r‌o‌c‌e‌s‌s o‌f c‌o‌l‌l‌a‌p‌s‌e, i‌s a‌b‌l‌e t‌o c‌a‌r‌r‌y o‌u‌t s‌e‌q‌u‌e‌n‌t‌i‌a‌l a‌n‌a‌l‌y‌s‌i‌s, a‌s‌s‌u‌m‌i‌n‌g a‌n e‌l‌a‌s‌t‌o-p‌l‌a‌s‌t‌i‌c b‌e‌h‌a‌v‌i‌o‌r f‌o‌r m‌a‌t‌e‌r‌i‌a‌l‌s. A‌f‌t‌e‌r e‌a‌c‌h a‌n‌a‌l‌y‌s‌i‌s, p‌l‌a‌s‌t‌i‌c h‌i‌n‌g‌e‌s, f‌o‌r‌m‌e‌d i‌n s‌t‌r‌u‌c‌t‌u‌r‌a‌l m‌e‌m‌b‌e‌r‌s, a‌r‌e i‌d‌e‌n‌t‌i‌f‌i‌e‌d. S‌t‌r‌u‌c‌t‌u‌r‌a‌l e‌l‌e‌m‌e‌n‌t‌s w‌h‌i‌c‌h s‌a‌t‌i‌s‌f‌y f‌a‌i‌l‌u‌r‌e c‌r‌i‌t‌e‌r‌i‌o‌n a‌r‌e r‌e‌m‌o‌v‌e‌d a‌n‌d t‌h‌e‌n t‌h‌e g‌e‌o‌m‌e‌t‌r‌y o‌f t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e i‌s u‌p‌d‌a‌t‌e‌d. T‌h‌e d‌e‌f‌o‌r‌m‌e‌d s‌h‌a‌p‌e o‌f t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e, i‌n e‌a‌c‌h s‌t‌a‌g‌e o‌f c‌o‌l‌l‌a‌p‌s‌e a‌f‌t‌e‌r r‌e‌m‌o‌v‌i‌n‌g e‌a‌c‌h d‌e‌s‌t‌r‌o‌y‌e‌d m‌e‌m‌b‌e‌r‌s, i‌s v‌i‌s‌u‌a‌l‌i‌z‌e‌d. T‌h‌e c‌o‌l‌l‌a‌p‌s‌e s‌t‌a‌g‌e‌s o‌f t‌h‌r‌e‌e s‌e‌l‌e‌c‌t‌e‌d b‌u‌i‌l‌d‌i‌n‌g‌s, i‌n‌t‌r‌o‌d‌u‌c‌e‌d i‌n p‌r‌e‌v‌i‌o‌u‌s‌l‌y p‌u‌b‌l‌i‌s‌h‌e‌d p‌a‌p‌e‌r‌s, i‌n‌v‌e‌s‌t‌i‌g‌a‌t‌e‌d a‌n‌d t‌h‌e c‌o‌m‌p‌u‌t‌e‌r s‌o‌f‌t‌w‌a‌r‌e i‌s v‌e‌r‌i‌f‌i‌e‌d. I‌n a d‌i‌f‌f‌e‌r‌e‌n‌t c‌a‌s‌e s‌t‌u‌d‌y t‌h‌e p‌r‌o‌c‌e‌s‌s o‌f t‌h‌e c‌o‌l‌l‌a‌p‌s‌e o‌f a 20 s‌t‌o‌r‌y b‌u‌i‌l‌d‌i‌n‌g h‌a‌s b‌e‌e‌n p‌r‌e‌d‌i‌c‌t‌e‌d f‌o‌r f‌o‌u‌r s‌c‌e‌n‌a‌r‌i‌o‌s o‌f c‌o‌n‌t‌r‌o‌l‌l‌e‌d d‌e‌m‌o‌l‌i‌t‌i‌o‌n. I‌t i‌s s‌h‌o‌w‌n t‌h‌a‌t t‌h‌e s‌o‌f‌t‌w‌a‌r‌e c‌a‌n b‌e u‌s‌e‌d t‌o p‌r‌e‌d‌i‌c‌t p‌r‌o‌g‌r‌e‌s‌s‌i‌v‌e c‌o‌l‌l‌a‌p‌s‌e o‌f t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e‌s

    The Causal Nexus among Energy Consumption, Environmental Degradation, Financial Development and Health Outcome: Empirical Study for Pakistan

    No full text
    Pakistan is facing an energy crisis and is also severely affected by climate change. Moreover, Pakistan is not doing well as far as health outcome indicators are concerned. The causal nexus among energy, environment, and health outcomes is well-established in literature. Besides, financial development also grabs the attention of health outcome literature as financial development can play a significant role in improving health outcomes. Thus, this study was conducted to test the causal nexus among energy consumption, environmental degradation, financial development, and health outcomes in the case of Pakistan. This study proxies health outcomes with life expectancy and infant mortality. Time series data have been analyzed through different econometric techniques, such as unit root tests, cointegration techniques, causality techniques, and cointegration regressions. Moreover, this study not just discovers the causal direction among variables but also determines the strength of causality through variance decomposition. Results of the study confirm that all variables of the study are cointegrated in the long run. The causality analysis reveals that unidirectional causality is running from energy consumption and environmental degradation to health outcomes, whereas bidirectional causality is found between financial development and health outcomes in the long run. Besides, this study also determines the effect of energy, environmental degradation, and financial development in the health outcome model and finds that energy and financial development can help Pakistan to improve health outcomes. Policy implications are recommended for Pakistan

    Order statistics using fuzzy random variables

    No full text
    This paper proposes a new method for the fuzzy order statistics. In this approach we will make use of the order statistics and develop this method for a fuzzy random sample.

    Seasonal study of serumic zinc levels in cows suspected of deficiency and its relationship with diet in industrial dairy farms of Urmia

    No full text
    Considering the very important role of zinc in structural and physiological functions of livestock body and the paucity of research in the regions, the objective of this study was to investigate zinc deficiency in cows suspected of deficiency in industrial dairy farms of Urmia and its relationship with diet of the animals. In this study, blood samples were taken from cows suspected of deficiency including animals that had anorexia, decrease in production and most importantly infertility problems. Samples were also taken from the animals diets. Sampling was conducted on a seasonal basis and 25 serum samples were collected in each season. Measurement was performed using atomic absorption method and serumic levels were calculated in micromoles. The results of this study indicated that in the animals suspected of zinc deficiency, there was no significant difference between different seasons but zinc levels were below normal in winter, spring and autumn. It is probable that dietary zinc deficiency especially low zinc levels in concentrate diets in the main cause of low zinc values in this study

    Strategie numeriche “industry-oriented” per la progettazione termo-meccanica di componenti per impianti siderurgici

    No full text
    Questo lavoro descrive alcune strategie numeriche per affrontare problematiche tipiche della progettazione termo-meccanica di componenti per l’industria siderurgica. Sebbene le analisi debbano includere fenomeni complessi come plasticità a differenti temperature, fatica termica, transizione di fase, è necessario che i modelli implementati soddisfino anche i requisiti industriali legati alla rapidità di calcolo e alla possibilità di ottenere risultati accurati senza far ricorso a formulazioni complesse o a onerose prove sperimentali. Si affronterà il calcolo termico di un componente che, lavorando a contatto con metallo ad elevata temperatura, incorre in parziale fusione. Verrà poi presentata una metodologia basata su elementi finiti di tipo armonico per lo studio delle sollecitazioni su rulli di laminazione. Infine si discuterà la metodologia di scelta dei modelli di plasticità ciclica da utilizzarsi per l’analisi numerica di una lingottiera per colata continua

    Botulinum-A toxin in the treatment of urinary incontinence due to overactive bladder following spinal cord injury

    No full text
    Background: We evaluated the efficacy of botulinum-A toxin (BTX-A) injection into detrusor muscle in patients with incontinence resistant to anticholinergic drugs due to detrusor overactivity.Methods: Our prospective study included 12 male patients with detrusor overactivity and incontinence due to spinal cord injury, which had been unsuccessfully treated with anticholinergic medication. Under visual control through the cystoscope 300 units of BTX-A were injected into detrusor muscle at 30 sites, sparing the trigone. After the treatment patients continued to perform clean intermittent self-catheterization (CIC) and clinical follow-up was planned for 6 weeks, 6 months and 9 months after treatment and urodynamic study was repeated after 6 weeks.Results: At the 6-week follow-up complete continence was restored in  9 of the 12 patients and after 6 months of 9 continent patients 1 patient lost his follow-up  from the study and 7 were still continent. After 9 months 3 patients remained continent. Mean cystometric bladder capacity (p<0.001), compliance (p<0.001), and mean post-void residual urine volume significantly increased (p<0.001), whereas maximal detrusor contraction pressure significantly decreased (p<0.001).Conclusions: BTX-A injections appears to be an effective and safe therapeutic option for overactive bladder in adult patients with spinal cord injury failing anticholinergic therapy even if these patients present with very low bladder compliance. Patients may require repeated injections after 6 months to remain continent

    Electrocardiographic findings in cattle with theileriosis

    No full text
    Theileriosis is an important protozoal disease of domestic ruminants especially cattle, sheep and goats which is transmitted by various species of Theileria infected ticks. Anemia, electrolytic disorders and vasculitis are amongst the cardiovascular complications of theileriosis. In this study, 90 cows with theileriosis were evaluated by clinical examination, parasitologic tests and electrocardiography. In Theileria infected cattle, after 30 minutes of rest and any treatment, a 30 second ECG was recorded in lead I to determine the types of arrhythmias present. Based on electrocardiographic findings frequently observed arrhythmias included 62 cases of sinus tachycardia, 15 cases of sinus arrhythmia, 6 cases of first degree atrio-ventricular block, 1 case of ventricular extra systole and 1 case of atrial fibrillation. According to the type of arrhythmias, it can be concluded that arrhythmias in cows with theileriosis are functional and nonpathologic
    corecore