Polymorphism: an evaluation of the potential risk to the quality of drug products from the Farmácia Popular Rede Própria

Polymorphism in solids is a common phenomenon in drugs, which can lead to compromised quality due to changes in their physicochemical properties, particularly solubility, and, therefore, reduce bioavailability. Herein, a bibliographic survey was performed based on key issues and studies related to polymorphism in active pharmaceutical ingredient (APIs) present in medications from the Farmácia Popular Rede Própria. Polymorphism must be controlled to prevent possible ineffective therapy and/or improper dosage. Few mandatory tests for the identification and control of polymorphism in medications are currently available, which can result in serious public health concerns

Metallurgical aspects of corrosion resistance of aluminium alloys

International audienceAluminium is the second most often used metal after steel. In this paper, the most current uses of aluminium alloys are first summarised. Then, their different corrosion modes, i.e. pitting, crevice, filiform, galvanic and structural corrosion (including inter-granular, exfoliation and stress corrosion cracking) are reviewed, with particular attention paid to metallurgical factors controlling the corrosion process. For each mode, some instances of possible in-service failure are given, followed by the discussion of the involved mechanisms and the presentation of appropriate solutions to prevent corrosion. Last, passivity and polarisation behaviour are discussed with reference to stainless steels

L'inégale répartition de la terre et des moyens de travail entre les agriculteurs, cause économique fondamentale de l'inégalité de leurs revenus

Reboul Claude, Al Hamchari M.C. L'inégale répartition de la terre et des moyens de travail entre les agriculteurs, cause économique fondamentale de l'inégalité de leurs revenus. In: Économie rurale. N°106, 1975. Population et travail agricoles (fin) pp. 15-22