Perceived care and well-being of patients with cancer and matched norm participants in the COVID-19 crisis:Results of a survey of participants in the Dutch PROFILES registry

Importance As the resolution of the coronavirus disease 2019 (COVID-19) crisis is unforeseeable, and/or a second wave of infections may arrive in the fall of 2020, it is important to evaluate patients’ perspectives to learn from this. Oblective To assess how Dutch patients with cancer perceive cancer treatment and follow-up care (including experiences with telephone and video consultations [TC/VC]) and patients’ well-being in comparison with a norm population during the COVID-19 crisis. Design, setting, and participants Cross-sectional study of patients participating in the Dutch Patient Reported Outcomes Following Initial Treatment and Long-term Evaluation of Survivorship (PROFILES) registry and a norm population who completed a questionnaire from April to May 2020. Main outcomes and measures Logistic regression analysis assessed factors associated with changes in cancer care (treatment or follow-up appointment postponed/canceled or changed to TC/VC). Differences in quality of life, anxiety/depression, and loneliness between patients and age-matched and sex-matched norm participants were evaluated with regression models. Results The online questionnaire was completed by 4094 patients (48.6% response), of whom most were male (2493 [60.9%]) and had a mean (SD) age of 63.0 (11.1) years. Of these respondents, 886 (21.7%) patients received treatment; 2725 (55.6%) received follow-up care. Treatment or follow-up appointments were canceled for 390 (10.8%) patients, whereas 160 of 886 (18.1%) in treatment and 234 of 2725 (8.6%) in follow-up had it replaced by a TC/VC. Systemic therapy, active surveillance, or surgery were associated with cancellation of treatment or follow-up appointment. Younger age, female sex, comorbidities, metastasized cancer, being worried about getting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and receiving supportive care were associated with replacement of a consultation with a TC/VC. Patients and norm participants reported that the COVID-19 crisis made them contact their general practitioner (852 of 4068 [20.9%] and 218 of 979 [22.3%]) or medical specialist/nurse (585 of 4068 [14.4%] and 144 of 979 [14.7%]) less quickly when they had physical complaints or concerns. Most patients who had a TC/VC preferred a face-to-face consultation, but 151 of 394 (38.3%) were willing to use a TC/VC again. Patients with cancer were more worried about getting infected with SARS-CoV-2 compared with the 977 norm participants (917 of 4094 [22.4%] vs 175 of 977 [17.9%]). Quality of life, anxiety, and depression were comparable, but norm participants more often reported loneliness (114 of 977 [11.7%] vs 287 of 4094 [7.0%]) than patients with cancer (P = .009). Conclusions and relevance Among patients with cancer in the Netherlands, 1 in 3 reported changes in cancer care in the first weeks of the COVID-19 crisis. Long-term outcomes need to be monitored. The crisis may affect the mental well-being of the general population relatively more than that of patients with cancer

Mesure par interférométrie optique de facteurs de Landé du xénon

Measurements of gj factors of some excited levels of xenon have been performed with a Fabry-Perot interferometer, using a pure even isotope. Levels 6s[3/2]1, 6p'[3/2]1, 7p[1/2]1, 7p[3/2]1, 7p[3/2]2 and 5f[3/2]1 have been studied from transitions located between 4 800 and 5 800 Å. The precision is near 10-4. The measurements of the three Zeeman sublevels of 5f[3/2]1 level as function of the magnetic field allow a test to be made of a calculation of the wavefunctions of the 5p5 5f configuration.Les facteurs de Landé de quelques niveaux excités du xénon ont été mesurés par interférométrie Fabry-Perot à partir d'un isotope pair. Les niveaux 6s[3/2]1, 6p'[3/2]1, 7p[1/2]1, 7p[3/2]1, 7p[3/2]2 et 5f[3/2]1 ont été étudiés grâce à des transitions comprises entre 4 800 et 5 800 Å. Les précisions sont de quelque 10-4. La mesure du déplacement des trois sous-niveaux Zeeman du niveau 5f[3/2]1 en fonction du champ magnétique permet de tester un calcul des fonctions d'onde de la configuration 5p5 5f

Wavelengths and lifetime measurements in He-like Cr XXIII and Li-like Cr XXII

Two and three electron spectra have been investigated in a beam-foil experiment with a chromium ion beam at 7 MeV/amu. The He-like Cr XXIII (Cr 22 +) 3S1- 3P2 transition is measured at 325.36 ± 0.5 Å, giving a transition energy of 307 350 (360) cm-1; this value is compared to the theoretical values given by De Serio et al. [1] and Hata and Grant [2]. A higher accuracy would be needed to provide a good test of the two-electron QED effects. The Li-like Cr XXII (Cr 21 +) 2S 1/2 - 2P3/2 transition is found at 222.97 ± 0.05 Å leading to a transition energy of 448 490 (102) cm -1 in very good agreement both with previous measurements in a tokamak plasma [9] and with theoretical predictions [3, 13b].Les spectres du chrome à 2 ou 3 électrons ont été étudiés dans une expérience faisceau-lame d'un faisceau d'ions chrome de 7 MeV/uma. On mesure la longueur d'onde de la raie 3S1 - 3P2 du Cr XXIII héliumoïde (Cr 22 + ) à 325,36 ± 0,5 Å soit à une énergie de 307 350 (360) cm-1, cette valeur est comparée aux résultats théoriques de De Serio et al. [1] et de Hata et Grant [2]. Il faudrait obtenir une meilleure précision pour que cette mesure soit un test probant des effets EDQ à deux électrons. On mesure aussi la longueur d'onde de la transition 2S 1/2 - 2P3/2 du Cr XXII lithiumoïde (Cr 21 +) à 222,97 ± 0,05 Å. L'énergie correspondante est de 448 490 (102) cm -1 en très bon accord avec une mesure antérieure dans un plasma de tokamak [9] et avec des prévisions théoriques [3, 13b]

Détermination de la structure fine des états doublement excités 1s 2s 2p 4P° et 1s 2p2 4P et de la durée de vie du niveau 1s 2p2 4P1/2 de Al XI

Using the beam-foil technique with an aluminium ion beam at 1.16 MeV/amu we have measured the fine structure of the 1s 2s 2p 4P0 and 1s 2p2 4P terms in lithium-like Al XI, the wavelengths of transitions between them, and the lifetime of the 1s 2p2 4P1/2 level. Our results are compared with the Hartree-Fock and the multiconfiguration Dirac-Fock calculations.Nous avons mesuré les longueurs d'onde de structure fine des transitions 1s 2s 2p 4P0-1s 2p2 4P et la durée de vie de l'état 1 s 2p2 4P1/2 de Al XI par spectroscopie d'un faisceau d'ions accélérés à 1,16 MeV/nucléon et excités dans une feuille mince de carbone. Nous comparons nos résultats aux valeurs obtenues par divers calculs Hartree-Fock et Dirac-Fock multiconfigurationnel

Sexual quality of life of adolescents and young adult breast cancer survivors

Background: With increasing survival rates of adolescents and young adults (AYAs) with breast cancer, health-related quality of life (HRQoL) becomes more important. An important aspect of HRQoL is sexual QoL. This study examined long-term sexual QoL of AYA breast cancer survivors, compared sexual QoL scores with that of other AYA cancer survivors, and identified factors associated with long-term sexual QoL of AYA breast cancer survivors. Materials and methods: Data of the SURVAYA study were utilized for secondary analyses. Sexual QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire (EORTC QLQ-SURV100). Descriptive statistics were used to describe sexual QoL of AYA cancer survivors. Linear regression models were constructed to examine the effect of cancer type on sexual QoL and to identify factors associated with sexual QoL. Results: Of the 4010 AYA cancer survivors, 944 had breast cancer. Mean sexual QoL scores of AYA breast cancer survivors ranged from 34.5 to 60.0 for functional domains and from 25.2 to 41.5 for symptom-orientated domains. AYA breast cancer survivors reported significantly lower sexual QoL compared to AYA survivors of other cancer types on all domains. Age, time since diagnosis, relationship status, educational level, chemotherapy, hormonal therapy, breast surgery, body image, and coping were associated with sexual QoL of AYA breast cancer survivors. Conclusions: AYA breast cancer survivors experience decreased sexual QoL in the long term (5-20 years) after diagnosis and worse score compared to AYA survivors of other cancer types, indicating a clear need to invest in supportive care interventions for those at risk, to enhance sexual well-being.</p

AYAs' online information and eHealth needs: A comparison with healthcare professionals' perceptions.

BACKGROUND: Adolescents and young adults (AYAs) diagnosed with cancer fulfill their cancer-related information needs often via the Internet. Healthcare professionals (HCPs) have a crucial role in guiding patients in finding appropriate online information and eHealth sources, a role that is often overlooked. Misperceptions of AYAs' needs by HCPs may lead to suboptimal guidance. We aimed to examine the extent to which AYAs' online information and eHealth needs corresponded with HCPs' perceptions of these needs. METHODS: Two cross-sectional online surveys (AYAs, n = 299; HCP, n = 80) on online information and eHealth needs were conducted. HCPs provided indications of their perceptions of AYA's needs. RESULTS: AYAs reported significantly more online information needs compared with HCPs' perceptions regarding: survival rates (AYA = 69%, HCP = 35%, p < 0.001), treatment guidelines (AYA = 65%, HCP = 41%, p < 0.001), return of cancer (AYA = 76%, HCP = 59%, p = 0.004), "what can I do myself" (AYA = 68%, HCP = 54%, p = 0.029), and metastases (AYA = 64%, HCP = 50%, p = 0.040). Significantly more unmet eHealth needs were reported by AYAs compared with HCPs relating to access to own test results (AYA = 25, HCP = 0%, p < 0.001), request tests (AYA = 30%, HCP = 7%, p < 0.001), medical information (AYA = 22%, HCP = 0%, p = 0.001), e-consult with nurses (AYA = 30%, HCP = 10%, p < 0.001), e-consult with physicians (AYA = 38%, HCP = 13%, p = 0.001), and request prescriptions (AYA = 33%, HCP = 21%, p = 0.009). CONCLUSION: AYAs' online information and eHealth needs are partially discrepant with the impression HCPs have, which could result in insufficient guidance related to AYAs' needs. AYAs and HCPs should get guidance regarding where to find optimal information in a language they understand. This may contribute to AYAs' access, understanding, and satisfaction regarding online information and eHealth

Notes on the lesser white-lined bat, Saccopteryx leptura (Schreber) (Chiroptera, Emballonuridae), from southeastern Brazil

Saccopteryx leptura (Schreber, 1774) is reported from two new localities in southeastern Brazil, both in Atlantic forest remains in the state of Rio de Janeiro. Analysisof food material showed that individuals from both localities had preyedon insects in the order Hymenoptera. Cheek contents were available from one specimen, and in this case identification of the food item (flying ants) achieved generic level (Pheidole Westwood, 1841). Aspects in the social behavior observed in a colony suggest that the same traits documented in Central American populations (small colonies, monogamic mating system, and retention of young for up to a year in the parental unit) may also characterize this species in the southern most part of its range. In both external and craniodental selected measurements, specimens from Rio de Janeiro were close to the upper limits of the ranges known for the species