Scientific integrity: Revisiting the concept

info:eu-repo/semantics/publishedVersio

Addressing conflicts of interest in the research paper: a societal demand in contemporary science?

In the last decade, dialogue between science and society has found a forum in an increasing number of publications on topics such as public engagement with science and public trust in science. Concerning the latter, issues that include cases of research misconduct, accountability in research, and conflicts of interest (COIs) have shaped global discussions on the communication of science. In the publication setting, the perception that hiding COIs and/or not managing them well may affect public trust in the research record has grown among editors. We conducted a search for editorials addressing COIs between 1989 and 2011, using four major databases: Medline/PubMed, Embase, Scopus, and Web of Knowledge. We explored the content of these editorials and the relationship they established between COIs and the public trust in science. Our results demonstrate that the relationship between disclosure of COIs and public trust in science has become a major concern among editors. We, thus, argue that COIs should be discussed more openly and frequently in graduate courses in the sciences, around the globe, not only in biomedical but also in non-biomedical areas. This is a critical issue in contemporary science, as graduate students are the future voices and decision-makers of the research community. Therefore, COIs, especially in the broader context of science and society, merit closer attention from policymakers, researchers, and educators. At times of great expectations for public engagement with science, mishandling of COIs may have undesirable consequences for public engagement with science and confidence in the scientific endeavor

Performance of the visual analogue scale of happiness and of the Cornell scale for depression in dementia in the tremembé epidemiological study, Brazil [Desempenho Na Escala Analógica Visual De Felicidade E Na Escala Cornell De Depressão Em Demência No Estudo Epidemiológico De Tremembé, Brasil]

Made available in DSpace on 2019-09-12T16:26:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2014Depression is a major growing public health problem. Many population studies have found a significant relationship between depression and the presence of cognitive disorders. Objective: To establish the correlation between the Visual Analogue Scale of Happiness and the Cornell Scale for Depression in Dementia in the population aged 60 years or over in the city of Tremembé, state of São Paulo, Brazil. Methods: An epidemiological survey involving home visits was carried out in the city of Tremembé. The sample was randomly selected by drawing 20% of the population aged 60 years or older from each of the city’s census sectors. In this single-phase study, the assessment included clinical history, physical and neurological examination, cognitive evaluation, and application of both the Cornell Scale and the Analogue Scale of Happiness for psychiatric symptoms. The presence of depressive symptoms was defined as scores greater than or equal to 8 points on the Cornell Scale. Results: A total of 623 subjects were evaluated and of these 251 (40.3%) had clinically significant depressive symptoms on the Cornell Scale, with a significant association with female gender (p<0.001) and with lower education (p=0.012). One hundred and thirty-six participants (21.8%) chose the unhappiness faces, with a significant association with age (p<0.001), female gender (p=0.020) and low socioeconomic status (p=0.012). Although there was a statistically significant association on the correlation test, the correlation was not high (rho=0.47).  Conclusion: The prevalence of depressive symptoms was high in this sample and the Visual Analogue Scale of Happiness and Cornell Scale for Depression in Dementia should not be used as similar alternatives for evaluating the presence of depressive symptoms, at least in populations with low educational level. © 2014, Academia Brasileira de Neurologia. All rights reserved.César, K.G., Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, Brazil, University of Taubaté, BrazilBrucki, S.M., Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilTakada, L.T., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilNascimento, L.F.C., University of Taubaté, BrazilGomes, C.M., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilAlmeida, M.C., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilOliveira, M.O., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilPorto, F.H., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilSenaha, M.L., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilBahia, V.S., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilSilva, T.B.L., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilIanof, J.N., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilSpíndola, L., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilSchmidt, M.T., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilJorge, M.S., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilVale, P.H., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilCecchini, M.A., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilCassimiro, L., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilSoares, R.T., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilGonçalves, M.R., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilSmid, J., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilPorto, C.S., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilCarthery-Goulart, M.T., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilYassuda, M.S., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilMansur, L.L., Epidemiologic Study (TES) Group, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, BrazilNitrini, R., University of São Paulo Medical School, Cognitive and Behavioral Neurology Unit, Department of Neurology, University of São Paulo, Brazi