Intracranial Cerebrospinal Fluid Volume as a Predictor of Malignant Middle Cerebral Artery Infarction

Background and Purpose— Predicting malignant middle cerebral artery (MCA) infarction can help to identify patients who may benefit from preventive decompressive surgery. We aimed to investigate the association between the ratio of intracranial cerebrospinal fluid (CSF) volume to intracranial volume (ICV) and malignant MCA infarction. Methods— Patients with an occlusion proximal to the M3 segment of the MCA were selected from the DUST (Dutch Acute Stroke Study). Admission imaging included noncontrast computed tomography (CT), CT perfusion, and CT angiography. Patient characteristics and CT findings were collected. The ratio of intracranial CSF volume to ICV (CSF/ICV) was quantified on admission thin-slice noncontrast CT. Malignant MCA infarction was defined as a midline shift of >5 mm on follow-up noncontrast CT, which was performed 3 days after the stroke or in case of clinical deterioration. To test the association between CSF/ICV and malignant MCA infarction, odds ratios and 95% CIs were calculated for 3 multivariable models by using binary logistic regression. Model performances were compared by using the likelihood ratio test. Results— Of the 286 included patients, 35 (12%) developed malignant MCA infarction. CSF/ICV was independently associated with malignant MCA infarction in 3 multivariable models: (1) with age and admission National Institutes of Health Stroke Scale (odds ratio, 3.3; 95% CI, 1.1–11.1), (2) with admission National Institutes of Health Stroke Scale and poor collateral score (odds ratio, 7.0; 95% CI, 2.6–21.3), and (3) with terminal internal carotid artery or proximal M1 occlusion and poor collateral score (odds ratio, 7.7; 95% CI, 2.8–23.9). The performance of model 1 (areas under the receiver operating characteristic curves, 0.795 versus 0.824; P=0.033), model 2 (areas under the receiver operating characteristic curves, 0.813 versus 0.850; P<0.001), and model 3 (areas under the receiver operating characteristic curves, 0.811 versus 0.856; P<0.001) improved significantly after adding CSF/ICV. Conclusions— The CSF/ICV ratio is associated with malignant MCA infarction and has added value to clinical and imaging prediction models in limited numbers of patients

Fourier Reconstruction of Irregularly Sampled Seismic Data

Civil Engineering and Geoscience

Veel potentie voor zakelijke mediation : Wat zijn de ervaringen van de afnemers van zakelijke mediation en welke ontwikkelingen in het vakgebied zien zij graag?

The report ‘ZAM/ACB research on possibilities and impediments for commercial mediation’ of the Utrecht Montaigne Centre represents the most important results for the three target groups (lawyers, firms, and judges), with an accent on how users of commercial mediation in the Netherlands think about the potential of mediation

Parabolic Radon transform and x-squared fk-transform - aliasing and efficiency

this paper the aliasing is studied by comparing the PRT with the Nonuniform Discrete Fourier Transform (NDFT). Although we find the same main principals, there are some differences. Moreover, the new points of view can provide a better understanding of the results found. The similarity between the PRT and the NDFT can also be used for the utilization of fast algorithms

Nonuniform fast Fourier transform

The nonuniform discrete Fourier transform (NDFT) can be computed with a fast algorithm, referred to as the nonuniform fast Fourier transform (NFFT). In L dimensions, the NFFT requires O(N(-ln #) L + ( Q L #=1 M # ) P L #=1 log M # ) operations, where M # is the number of Fourier components along dimension #, N is the number of irregularly spaced samples, and # is the required accuracy. This is a dramatic improvement over the O(N Q L #=1 M # ) operations required for the direct evaluation (NDFT). The performance of the NFFT depends on the lowpass filter used in the algorithm. A truncated Gauss pulse, proposed in the literature, is optimized. A newly proposed filter, a Gauss pulse tapered with a Hanning window, performs better than the truncated Gauss pulse and the B-spline, also proposed in the literature. For small filter length, a numerically optimized filter shows the best results. Numerical experiments for 1-D and 2-D implementations confirm the theoretically predicted ..

Mixed Fourier-Radon reconstruction of irregularly and sparsely sampled seismic data

Seismic data irregularly sampled in two dimensions is transformed to the Fourier/Radon domain using a least squares formulation where the inverse transform, from the Fourier/Radon to the spatial domain is used as a forward model. By a proper choice of the region of support, the total number of parameters is limited (yet such that the actual data is optimally contained), leading to a stable inversion. Subsequently the data can be transformed to any desired grid in the spatial domain. Also, using suitable transforms, signal and noise map to different parts of the transform domain and can be separated. The method is applied to synthetic and marine data. I. Introduction In exploration seismology structural information of the subsurface is obtained by recording the wavefield generated by a source (e.g. dynamite), using many receivers. In 2D seismics, these receivers are positioned along a line at the surface with sampling interval \Deltax r and starting at a certain &apos;offset&apos; x 0 from the..

Oil Palm (Elaeis guineensis Jacq.) Frond Feeding of Goats in the Humid Tropics

Twenty four goats were allocated to three groups (n = 8) and fed either a control diet Without Oil Palm Fronds (CON), a diet incorporated with 25% Oil Palm Fronds (OPFM) or 50% Oil Palm Fronds (OPFH) for 100 days to evaluate their growth rates, carcass characteristics and subcutaneous fatty acid profiles. Animals in all three groups exhibited similar final body weights (p>0.05). The OPFH group showed a significant linear reduction (p<0.05) in dressing percentage, warm carcass weight and back fat thickness and total muscle when compared to the CON group. The total n-3 Polyunsaturated Fatty Acid (PUFA) concentrations in the subcutaneous fat of the OPFH animals were significantly higher (linear, p<0.05) than the CON group. The diet containing 25% of oil palm fronds did not produce any adverse effects on the growth performance and carcass characteristics. This demonstrates an environmental-friendly way of utilizing agricultural waste by products for the small ruminant industry in tropical countries growing oil palm tree

Physical exercise prepartum to support metabolic adaptation in the transition period of dairy cattle : A proof of concept

In dairy cattle, the hormonal changes around calving induce large metabolic changes to support milk production. Mobilization of adipose reserves is one of the changes involved, imposing a metabolic load on the liver. We hypothesized that the risk for excessive lipolysis and hepatic lipidosis postpartum can be reduced by starting fat mobilization and processing during the prepartum period by physical exercise, especially in cows with a high body condition score (BCS). As a proof of concept, 32 pregnant Holstein-Friesian dairy cows were selected for a 2 × 2 experimental design. Sixteen cows had a BCS < 3.25 (group LOW) and 16 cows a BCS ≥ 3.25 (group HIGH). Cows within each group were randomly allocated to one of two treatments: group STEP was walked twice daily for 45 min during the dry period while group CON remained indoors. Treatment was stopped at calving and cows were monitored until 6 weeks after calving. Liver biopsies were taken in a subset of 16 cows to determine liver triglyceride (TG) concentration. We found that calculated energy balance was more negative for group STEP prepartum, resulting in higher plasma non-esterified fatty acids and β-hydroxybutyrate concentrations. During the first 6 weeks postpartum, neither dry matter intake nor milk yield was affected by exercise. As expected, the cows in group HIGH had increased liver TG concentrations postpartum relative to group LOW with increased plasma non-esterified fatty acids directly after calving. Exercise during the dry period mitigated postpartal liver TG accumulation, but this did not seem to be related to increased plasma lipoprotein transport. We conclude that substantial physical activity prepartum can induce lipolysis and lipid utilization, thereby starting an early adaptation to lactation. This may be instrumental to reduce the risk for excessive liver TG accumulation postpartum, especially in cows with a high BCS at dry-off.</p

Veel potentie voor zakelijke mediation: Wat zijn de ervaringen van de afnemers van zakelijke mediation en welke ontwikkelingen in het vakgebied zien zij graag?

The report ‘ZAM/ACB research on possibilities and impediments for commercial mediation’ of the Utrecht Montaigne Centre represents the most important results for the three target groups (lawyers, firms, and judges), with an accent on how users of commercial mediation in the Netherlands think about the potential of mediation