502 research outputs found
Doing Justice - zur Praxis auĂerstrafrechtlicher Strategien der KonfliktbewĂ€ltigung in linksautonomen RĂ€umen
Die vorliegende Masterarbeit beschĂ€ftigt sich mit Strategien der auĂerstrafrechtlichen Konfliktbear- beitung in linksautonomen RĂ€umen. Ausgehend von der Annahme, dass staatliche Strafe ein Instrument der HerrschaftsausĂŒbung darstellt und in Zeiten des
Neoliberalismus die prekĂ€r gewordenen Grenzen der gesellschaftlichen Zugehörigkeit durch Kriminalisierung aufrechterhalten werden, sollen Alternativen zum hegemonialen Strafrechtssystem aufgezeigt werden. Das qualitative Forschungsdesign wurde unter BerĂŒcksichti-gung der Grundannahmen der Kritischen Kriminologie entwickelt. Durch den Konfliktbegriff wird sich von der Kategorie âKriminalitĂ€tâ mit den ihr inhĂ€renten
Zuschreibungen gelöst. Der Forschungsprozess basiert auf der Grounded Theory Methodologie. Auf der Grundlage teilnarrativer Interviews mit Aktivist*innen aus
verschiedenen linksautonomen RĂ€umen in Deutschland wird ein Modell entwickelt, welches den Prozess der selbstbestimmten Bearbeitung von konflikthaften Ereignissen im gewĂ€hlten Forschungsfeld beschreibt. Dieses zeigt auf, dass eine Aneignung von Konflikten verstĂ€rkt durch einen hohen Grad der VerantwortungsĂŒbernahme stattfindet. In einem zirkulĂ€ren Prozess werden hierbei in der Bearbeitung von Konflikten eigene Regeln und Werte entwickelt, welche sich wiederum auf den Umgang mit Konflikten auswirken. Die Ergebnisse der Forschung richten sich primĂ€r an Personen, welche in links-autonomen RĂ€umen aktiv sind und dienen einem besseren VerstĂ€ndnis ihrer gelebten Praxis. Durch die kritische Reflexion, unter BerĂŒcksichtigung der GrundsĂ€tze von Transformative Justice und Community Accountability, werden zudem Perspektiven fĂŒr eine mögliche Weiterentwicklung linksautonomer AnsĂ€tze zum Umgang mit Konflikten aufgezeigt
Long term variability of the blazar PKS 2155-304
International audienceTime variability of the photon flux is a known feature of active galactic nuclei (AGN) and in particular of blazars. The high frequency peaked BL Lac (HBL) object PKS 2155-304 is one of the brightest sources in the TeV band and has been monitored regularly with different instruments and in particular with the H.E.S.S. experiment above 200 GeV for more than 11 years. These data together with the observations of other instruments and monitoring programs like SMARTS (optical), Swift-XRT/RXTE/XMM-Newton (X-ray) and Fermi-LAT (100 MeV < E < 300 GeV) are used to characterize the variability of this object in the quiescent state over a wide energy range. Variability studies are made by looking at the lognormality of the light curves and at the fractional root mean square (rms) variability F var in several energy bands. Lognormality is found in every energy range and the evolution of F var with the energy shows a similar increase both in X-rays and in TeV bands
Role of Disorder on the Quantum Critical Point of a Model for Heavy Fermions
A zero temperature real space renormalization group (RG) approach is used to
investigate the role of disorder near the quantum critical point (QCP) of a
Kondo necklace (XY-KN) model. In the pure case this approach yields
implying that any coupling between the local moments and the
conduction electrons leads to a non-magnetic phase. We also consider an
anisotropic version of the model (), for which there is a quantum phase
transition at a finite value of the ratio between the coupling and the
bandwidth, . Disorder is introduced either in the on-site interactions
or in the hopping terms. We find that in both cases randomness is irrelevant in
the model, i.e., the disorder induced magnetic-non-magnetic quantum
phase transition is controlled by the same exponents of the pure case. Finally,
we show the fixed point distributions at the atractors of the
disordered, non-magnetic phases.Comment: 5 pages, 3 figure
Numerical Study of Competing Spin-Glass and Ferromagnetic Order
Two and three dimensional random Ising models with a Gaussian distribution of
couplings with variance and non-vanishing mean value are studied
using the zero-temperature domain-wall renormalization group (DWRG). The DWRG
trajectories in the () plane after rescaling can be collapsed on two
curves: one for and other for . In the first case
the DWRG flows are toward the ferromagnetic fixed point both in two and three
dimensions while in the second case flows are towards a paramagnetic fixed
point and spin-glass fixed point in two and three dimensions respectively. No
evidence for an extra phase is found.Comment: a bit more data is taken, 5 pages, 4 eps figures included, to appear
in PR
Local multi-channel RF surface coil versus body RF coil transmission for cardiac magnetic resonance at 3 Tesla: which configuration is winning the game?
INTRODUCTION: The purpose of this study was to demonstrate the feasibility and efficiency of cardiac MR at 3 Tesla using local four-channel RF coil transmission and benchmark it against large volume body RF coil excitation. METHODS: Electromagnetic field simulations are conducted to detail RF power deposition, transmission field uniformity and efficiency for local and body RF coil transmission. For both excitation regimes transmission field maps are acquired in a human torso phantom. For each transmission regime flip angle distributions and blood-myocardium contrast are examined in a volunteer study of 12 subjects. The feasibility of the local transceiver RF coil array for cardiac chamber quantification at 3 Tesla is demonstrated. RESULTS: Our simulations and experiments demonstrate that cardiac MR at 3 Tesla using four-channel surface RF coil transmission is competitive versus current clinical CMR practice of large volume body RF coil transmission. The efficiency advantage of the 4TX/4RX setup facilitates shorter repetition times governed by local SAR limits versus body RF coil transmission at whole-body SAR limit. No statistically significant difference was found for cardiac chamber quantification derived with body RF coil versus four-channel surface RF coil transmission. Our simulation also show that the body RF coil exceeds local SAR limits by a factor of ~2 when driven at maximum applicable input power to reach the whole-body SAR limit. CONCLUSION: Pursuing local surface RF coil arrays for transmission in cardiac MR is a conceptually appealing alternative to body RF coil transmission, especially for patients with implants
Decoherence of electron spin qubits in Si-based quantum computers
Direct phonon spin-lattice relaxation of an electron qubit bound by a donor
impurity or quantum dot in SiGe heterostructures is investigated. The aim is to
evaluate the importance of decoherence from this mechanism in several important
solid-state quantum computer designs operating at low temperatures. We
calculate the relaxation rate as a function of [100] uniaxial strain,
temperature, magnetic field, and silicon/germanium content for Si:P bound
electrons. The quantum dot potential is much smoother, leading to smaller
splittings of the valley degeneracies. We have estimated these splittings in
order to obtain upper bounds for the relaxation rate. In general, we find that
the relaxation rate is strongly decreased by uniaxial compressive strain in a
SiGe-Si-SiGe quantum well, making this strain an important positive design
feature. Ge in high concentrations (particularly over 85%) increases the rate,
making Si-rich materials preferable. We conclude that SiGe bound electron
qubits must meet certain conditions to minimize decoherence but that
spin-phonon relaxation does not rule out the solid-state implementation of
error-tolerant quantum computing.Comment: 8 figures. To appear in PRB-July 2002. Revisions include: some
references added/corrected, several typos fixed, a few things clarified.
Nothing dramati
High spatial resolution cardiovascular magnetic resonance at 7.0 Tesla in patients with hypertrophic cardiomyopathy - first experiences: lesson learned from 7.0 Tesla
BACKGROUND: Cardiovascular Magnetic Resonance (CMR) provides valuable information in patients with hypertrophic cardiomyopathy (HCM) based on myocardial tissue differentiation and the detection of small morphological details. CMR at 7.0T improves spatial resolution versus today's clinical protocols. This capability is as yet untapped in HCM patients. We aimed to examine the feasibility of CMR at 7.0T in HCM patients and to demonstrate its capability for the visualization of subtle morphological details. METHODS: We screened 131 patients with HCM. 13 patients (9 males, 56 +/-31 years) and 13 healthy age- and gender-matched subjects (9 males, 55 +/-31years) underwent CMR at 7.0T and 3.0T (Siemens, Erlangen, Germany). For the assessment of cardiac function and morphology, 2D CINE imaging was performed (voxel size at 7.0T: (1.4x1.4x2.5) mm3 and (1.4x1.4x4.0) mm3; at 3.0T: (1.8x1.8x6.0) mm3). Late gadolinium enhancement (LGE) was performed at 3.0T for detection of fibrosis. RESULTS: All scans were successful and evaluable. At 3.0T, quantification of the left ventricle (LV) showed similar results in short axis view vs. the biplane approach (LVEDV, LVESV, LVMASS, LVEF) (p = 0.286; p = 0.534; p = 0.155; p = 0.131). The LV-parameters obtained at 7.0T where in accordance with the 3.0T data (pLVEDV = 0.110; pLVESV = 0.091; pLVMASS = 0.131; pLVEF = 0.182). LGE was detectable in 12/13 (92%) of the HCM patients. High spatial resolution CINE imaging at 7.0T revealed hyperintense regions, identifying myocardial crypts in 7/13 (54%) of the HCM patients. All crypts were located in the LGE-positive regions. The crypts were not detectable at 3.0T using a clinical protocol. CONCLUSIONS: CMR at 7.0T is feasible in patients with HCM. High spatial resolution gradient echo 2D CINE imaging at 7.0T allowed the detection of subtle morphological details in regions of extended hypertrophy and LGE
The Random-bond Potts model in the large-q limit
We study the critical behavior of the q-state Potts model with random
ferromagnetic couplings. Working with the cluster representation the partition
sum of the model in the large-q limit is dominated by a single graph, the
fractal properties of which are related to the critical singularities of the
random Potts model. The optimization problem of finding the dominant graph, is
studied on the square lattice by simulated annealing and by a combinatorial
algorithm. Critical exponents of the magnetization and the correlation length
are estimated and conformal predictions are compared with numerical results.Comment: 7 pages, 6 figure
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients
Acute myeloid leukemia (AML) is a very heterogeneous and highly malignant blood cancer. Mutations of the DNA methyltransferase DNMT3A are among the most frequent recurrent genetic lesions in AML. The majority of DNMT3A-mutant AML patients shows fast relapse and poor survival, but also patients with long survival or long-term remission have been reported. Underlying molecular signatures and mechanisms that contribute to these survival differences are only poorly understood and have not been studied in detail so far. We applied hierarchical clustering to somatic gene mutation profiles of 51 DNMT3A-mutant patients from The Cancer Genome Atlas (TCGA) AML cohort revealing two robust patient subgroups with profound differences in survival. We further determined molecular signatures that distinguish both subgroups. Our results suggest that FLT3 and/or NPM1 mutations contribute to survival differences of DNMT3A-mutant patients. We observed an upregulation of genes of the p53, VEGF and DNA replication pathway and a downregulation of genes of the PI3K-Akt pathway in short- compared to long-lived patients. We identified that the majority of measured miRNAs was downregulated in the short-lived group and we found differentially expressed microRNAs between both subgroups that have not been reported for AML so far (miR-153-2, miR-3065, miR-95, miR-6718) suggesting that miRNAs could be important for prognosis. In addition, we learned gene regulatory networks to predict potential major regulators and found several genes and miRNAs with known roles in AML pathogenesis, but also interesting novel candidates involved in the regulation of hematopoiesis, cell cycle, cell differentiation, and immunity that may contribute to the observed survival differences of both subgroups and could therefore be important for prognosis. Moreover, the characteristic gene mutation and expression signatures that distinguished short- from long-lived patients were also predictive for independent DNMT3A-mutant AML patients from other cohorts and could also contribute to further improve the European LeukemiaNet (ELN) prognostic scoring system. Our study represents the first in-depth computational approach to identify molecular factors associated with survival differences of DNMT3A-mutant AML patients and could trigger additional studies to develop robust molecular markers for a better stratification of AML patients with DNMT3A mutations
Donor states in modulation-doped Si/SiGe heterostructures
We present a unified approach for calculating the properties of shallow
donors inside or outside heterostructure quantum wells. The method allows us to
obtain not only the binding energies of all localized states of any symmetry,
but also the energy width of the resonant states which may appear when a
localized state becomes degenerate with the continuous quantum well subbands.
The approach is non-variational, and we are therefore also able to evaluate the
wave functions. This is used to calculate the optical absorption spectrum,
which is strongly non-isotropic due to the selection rules. The results
obtained from calculations for Si/SiGe quantum wells allow us to
present the general behavior of the impurity states, as the donor position is
varied from the center of the well to deep inside the barrier. The influence on
the donor ground state from both the central-cell effect and the strain arising
from the lattice mismatch is carefully considered.Comment: 17 pages, 10 figure
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