A customizable open-source framework for measuring and equalizing e2e delays in shared video watching

Low-latency and media sync are essential requirements to enable interactive multi-party services, such as Social TV. In this work, we present an open-source and customizable framework that allows measuring end-to-end (e2e) video delays and provides support for different type

Impact of Social Media on TV Content Consumption: New Market Strategies, Scenarios and Trends

The mass adoption of Social Media together with the proliferation and widely usage of multi-connected companion devices have tremendously transformed the TV/video consumption paradigm, opening the door to a new range of possibilities. This Special Issue has aimed at analyzing, from different point of views, the impact of Social Media and social interaction tools on the TV/video consumption area. The targeted topics of this Special Issue and a general overview of the accepted articles are provided in this Guest Editorial

Wersync: A WEB-BASED PLATFORM FOR DISTRIBUTED MEDIA SYNCHRONIZATION AND SOCIAL INTERACTION

This paper presents Wersync, which is an adaptive and accurate web-based platform that enables distributed media synchronization and social interaction across remote users. By using Wersync, users can create or join on-going sessions for concurrently consuming the same media content with other remote users in a synchronized manner. Besides, social interaction is provided by sharing the navigation control commands and by integrating synchronized text chat channels. Additionally, two social presence mechanisms have been added to stimulate the participation of external users in on-going sessions on Wersync. By exclusively relying on standard web-based technologies, this platform can guarantee cross-network, cross-platform and crossdevice support, which is a key point in the current heterogeneous media delivery ecosystem

Review of Media Sync Reference Models: Advances and Open Issues

The advances on multimedia systems have brought new challenges and requirements for media sync. Over the years, many media sync solutions have been devised. Due to this variety, several studies have surveyed the existing solutions and proposed classification schemes or reference models for media sync. This paper claims the relevance of media sync reference models to systematically structure and synthesize this research area. Accordingly, a review of the existing reference models is provided, by examining the involved features, components and layers in each one of them. Likewise, some inconsistencies, open issues and missing components in existing reference models have been identified. Accordingly, this study reflects the need for a new modular and extensible theoretical framework or reference model to efficiently comprehend the overall media sync research area

Plataforma Web 2.0 para la Sincronización Distribuida de Contenidos Multimedia e Interacción Social

Shared media experiences between geographically distributed users are gaining momentum. Relevant examples are Social TV, synchronous e-learning and multi-player online games. This paper presents a first release of Wersync, an adaptive web-based platform that provides distributed media synchronization and social interaction (via shared navigation control commands and text chat channels) across remote users. By using Wersync, users can create or join on-going sessions for concurrently consuming the same media content with other remote users in a synchronized manner. Additionally, Wersync provides two social presence mechanisms to encourage the participation of external users in on-going sessions and two privacy mechanisms. Wersync has been developed by exclusively relying on standard web-based technologies, which ensures cross-network, cross-platform and cross-device support. The evaluation results and a link to a demo video prove the satisfactory performance of Wersync, and its functionalities, respectively

Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome

To identify recurrent genomic changes in mantle cell lymphoma (MCL), we used high-resolution comparative genomic hybridization (CGH) to bacterial artificial chromosome (BAC) microarrays in 68 patients and 9 MCL-derived cell lines. Array CGH defined an MCL genomic signature distinct from other B-cell lymphomas, including deletions of 1p21 and 11q22.3-ATM gene with coincident 10p12-BMI1 gene amplification and 10p14 deletion, along with a previously unidentified loss within 9q21-q22. Specific genomic alterations were associated with different subgroups of disease. Notably, 11 patients with leukemic MCL showed a different genomic profile than nodal cases, including 8p21.3 deletion at tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor gene cluster (55% versus 19%; P = .01) and gain of 8q24.1 at MYC locus (46% versus 14%; P = .015). Additionally, leukemic MCL exhibited frequent IGVH mutation (64% versus 21%; P = .009) with preferential VH4-39 use (36% versus 4%; P = .005) and followed a more indolent clinical course. Blastoid variants, increased number of genomic gains, and deletions of P16/INK4a and TP53 genes correlated with poorer outcomes, while 1p21 loss was associated with prolonged survival (P = .02). In multivariate analysis, deletion of 9q21-q22 was the strongest predictor for inferior survival (hazard ratio [HR], 6; confidence interval [CI], 2.3 to 15.7). Our study highlights the genomic profile as a predictor for clinical outcome and suggests that "genome scanning" of chromosomes 1p21, 9q21-q22, 9p21.3-P16/INK4a, and 17p13.1-TP53 may be clinically useful in MCL

Impacto de Parámetros de QoS en Aspectos de QoE: Análisis desde el Punto de Vista de la Sincronización Multimedia

La sincronización multimedia ha sido un área de investigación clave desde los inicios de los sistemas multimedia. En este artículo se ofrecen una visión general y un análisis sobre el impacto de varios parámetros de QoS en diferentes aspectos de la QoE, desde el punto de vista de la sincronización multimedia. En primer lugar, se presentan los diferentes tipos de sincronización multimedia y su relevancia para garantizar una QoE satisfactoria. En segundo lugar, se muestra que la magnitud de los retardos y su variabilidad en las redes actuales es bastante superior a los umbrales permisibles por los usuarios en diferentes tipos y ejemplos de sincronización multimedia, reflejando así su necesidad. En tercer lugar, se describe el impacto del ancho de banda y la tasa de pérdidas sobre la sincronización multimedia. Por último, se argumenta la influencia del uso de diferentes alternativas para conseguir la sincronización multimedia sobre varios factores de QoS y de QoE

Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study

Comparative genomic hybridization (CGH) studies have demonstrated a high incidence of chromosomal imbalances in non-Hodgkin's lymphoma. However, the information on the genomic imbalances in Burkitt's Lymphoma (BL) is scanty. Conventional cytogenetics was performed in 34 cases, and long-distance PCR for t(8;14) was performed in 18 cases. A total of 170 changes were present with a median of four changes per case (range 1-22). Gains of chromosomal material (143) were more frequent than amplifications (5) or losses (22). The most frequent aberrations were gains on chromosomes 12q (26%), Xq (22%), 22q (20%), 20q (17%) and 9q (15%). Losses predominantly involved chromosomes 13q (17%) and 4q (9%). High-level amplifications were present in the regions 1q23-31 (three cases), 6p12-p25 and 8p22-p23. Upon comparing BL vs Burkitt's cell leukemia (BCL), the latter had more changes (mean 4.3 +/- 2.2) than BL (mean 2.7 +/- 3.2). In addition, BCL cases showed more frequently gains on 8q, 9q, 14q, 20q, and 20q, 9q, 8q and 14q, as well as losses on 13q and 4q. Concerning outcome, the presence of abnormalities on 1q (ascertained either by cytogenetics or by CGH), and imbalances on 7q (P=0.01) were associated with a short survival

Medidas de Tromboprofilaxis en Artroplastia Total de Rodilla. Práctica habitual en la Comunidad Valenciana y revisión bibliográfica.

Antecedentes: El tromboembolismo es una complicación de la cirugía de artroplastia total de rodilla. Para su prevención disponemos de múltiples medidas físicas y farmacológicas.Objetivo:Conocer quémedidas de prevención tromboembólica son las empleadas por los cirujanos ortopédicos en cirugía protésica de rodilla primaria en diferentes centros hospitalarios de nuestra región.Método: Estudio transversal descriptivo observacional basado en encuesta dirigida a especialistas COT de 9 hospitales públicos de la Comunidad Valenciana y búsqueda bibliográfica.Resultados: Se obtuvieron 64 encuestas. Todos los cirujanos eligen HBPM durante un mes como medida de tromboprofilaxis, descartando anticoagulantes orales o aspirina. El 29% también emplea dispositivos de movilización pasiva. Conclusiones: Los cirujanos ortopédicos de la comunidad valenciana optan por HBPM conforme a las mejores evidencias. Se estima, que la incidencia de eventos tromboembólicos sintomáticos desciende del 4,3 % al 1,8% con el uso de HBPM. El empleo de dispositivos de movilización pasiva y medias de compresión no están avaladas por las evidencias. La estratificación preoperatoria del riesgo de tromboembolismo, para emplear ácido acetil salicílico asociado a bombas de presión intermitente en caso de no existir alto riesgo es una tendencia cada vez más aceptada internacionalmente