129 research outputs found
Elemental abundances of low-mass stars in nearby young associations: AB Doradus, Carina Near, and Ursa Major
We present stellar parameters and abundances of 11 elements (Li, Na, Mg, Al,
Si, Ca, Ti, Cr, Fe, Ni, and Zn) of 13 F6-K2 main-sequence stars in the young
groups AB Doradus, Carina Near, and Ursa Major. The exoplanet-host star \iota
Horologii is also analysed.
The three young associations have lithium abundance consistent with their
age. All other elements show solar abundances. The three groups are
characterised by a small scatter in all abundances, with mean [Fe/H] values of
0.10 (\sigma=0.03), 0.08 (\sigma=0.05), and 0.01 (\sigma=0.03) dex for AB
Doradus, Carina Near, and Ursa Major, respectively. The distribution of
elemental abundances appears congruent with the chemical pattern of the
Galactic thin disc in the solar vicinity, as found for other young groups. This
means that the metallicity distribution of nearby young stars, targets of
direct-imaging planet-search surveys, is different from that of old, field
solar-type stars, i.e. the typical targets of radial velocity surveys.
The young planet-host star \iota Horologii shows a lithium abundance lower
than that found for the young association members. It is found to have a
slightly super-solar iron abundance ([Fe/H]=0.16+-0.09), while all [X/Fe]
ratios are similar to the solar values. Its elemental abundances are close to
those of the Hyades cluster derived from the literature, which seems to
reinforce the idea of a possible common origin with the primordial cluster.Comment: 16 pages, 2 figures, 6 tables. Accepted for publication in MNRA
On the accretion properties of young stellar objects in the L1615/L1616 cometary cloud
We present the results of FLAMES/UVES and FLAMES/GIRAFFE spectroscopic
observations of 23 low-mass stars in the L1615/L1616 cometary cloud,
complemented with FORS2 and VIMOS spectroscopy of 31 additional stars in the
same cloud. L1615/L1616 is a cometary cloud where the star formation was
triggered by the impact of the massive stars in the Orion OB association. From
the measurements of the lithium abundance and radial velocity, we confirm the
membership of our sample to the cloud. We use the equivalent widths of the
H, H, and the HeI 5876, 6678, 7065
\AAemission lines to calculate the accretion luminosities, ,
and the mass accretion rates, . We find in L1615/L1616 a
fraction of accreting objects (), which is consistent with the
typical fraction of accretors in T associations of similar age ( Myr).
The mass accretion rate for these stars shows a trend with the mass of the
central object similar to that found for other star-forming regions, with a
spread at a given mass which depends on the evolutionary model used to derive
the stellar mass. Moreover, the behavior of the colors with indicates that strong accretors with dex show large excesses in the bands, as in previous
studies. We also conclude that the accretion properties of the L1615/L1616
members are similar to those of young stellar objects in T associations, like
Lupus.Comment: Accepted by Astronomy and Astrophysics. 17 pages, 11 figures, 6
table
X-shooter spectroscopy of young stellar objects in Lupus: Lithium, iron, and barium elemental abundances
With the purpose of performing a homogeneous determination of elemental
abundances for members of the Lupus T association, we analyzed three chemical
elements: lithium, iron, and barium. The aims were: to derive the Li abundance
for ~90% of known class II stars in the Lupus I, II, III, IV clouds; to perform
chemical tagging of a region where few Fe abundance measurements have been
obtained in the past, and no determination of the Ba content has been done up
to now. We also investigated possible Ba enhancement, as this element has
become increasingly interesting in the last years following the evidence of Ba
over-abundance in young clusters, the origin of which is still unknown. Using
X-shooter@VLT, we analyzed the spectra of 89 cluster members, both class II and
III stars. We measured the strength of the Li line and derived the abundance of
this element through equivalent width measurements and curves of growth. For
six class II stars we also measured the Fe and Ba abundances using the spectral
synthesis and the code MOOG. The veiling contribution was taken into account
for all three elements. We find a dispersion in the strength of the Li line at
low Teff and identify three targets with severe Li depletion. The nuclear age
inferred for these highly Li-depleted stars is around 15 Myr, which exceeds the
isochronal one. As in other star-forming regions, no metal-rich members are
found in Lupus, giving support to a recent hypothesis that the Fe abundance
distribution of most of the nearby young regions could be the result of a
common and widespread star formation episode involving the Galactic thin disk.
We find that Ba is over-abundant by ~0.7 dex with respect to the Sun. Since
current theoretical models cannot reproduce this Ba abundance pattern, we
investigated whether this unusually large Ba content might be related to
effects due to stellar parameters, stellar activity, and accretion.Comment: 15 pages, 14 figures, 3 tables; accepted for publication in A&A;
abstract shortene
Haplotypes of the genes (GCK and G6PC2) underlying the glucose/glucose-6-phosphate cycle are associated with pancreatic beta cell glucose sensitivity in patients with newly diagnosed type 2 diabetes from the VNDS study (VNDS 11)
Background: Elevated fasting plasma glucose has been associated with increased risk for development of type 2 diabetes (T2D). The balance between glucokinase (GCK) and glucose-6-phosphate catalytic subunit 2 (G6PC2) activity are involved in glucose homeostasis through glycolytic flux, and subsequent insulin secretion. Aim: In this study, we evaluated the association between the genetic variability of G6PC2 and GCK genes and T2D-related quantitative traits. Methods: In 794 drug-naïve, GADA-negative, newly diagnosed T2D patients (VNDS; NTC01526720) we performed: genotyping of 6 independent tag-SNPs within GCK gene and 5 tag-SNPs within G6PC2 gene; euglycaemic insulin clamp to assess insulin sensitivity; OGTT to estimate beta-cell function (derivative and proportional control; DC, PC) by mathematical modeling. Genetic association analysis has been conducted using Plink software. Results: Two SNPs within GCK gene (rs882019 and rs1303722) were associated to DC in opposite way (both p < 0.004). Two G6PC2 variants (rs13387347 and rs560887) were associated to both parameters of insulin secretion (DC and PC) and to fasting C-peptide levels (all p < 0.038). Moreover, subjects carrying the A allele of rs560887 showed higher values of 2h-plasma glucose (2hPG) (p = 0.033). Haplotype analysis revealed that GCK (AACAAA) haplotype was associated to decreased fasting C-peptide levels, whereas, the most frequent haplotype of G6PC2 (GGAAG) was associated with higher fasting C-peptide levels (p = 0.001), higher PC (β = 6.87, p = 0.022) and the lower 2hPG (p = 0.012). Conclusion: Our findings confirmed the role of GCK and G6PC2 in regulating the pulsatility in insulin secretion thereby influencing insulin-signaling and leading to a gradual modulation in glucose levels in Italian patients with newly diagnosed T2D
Early marker of ocular neurodegeneration in children and adolescents with type 1 diabetes: the contributing role of polymorphisms in mir146a and mir128a genes
Background: Early ocular neurodegenerative signs of diabetic neuropathy (DN) can be found in children and adolescents with type 1 diabetes (T1D). No data are available on the potential role of polymorphisms in miRNAs genes in predisposing T1D subjects to these signs. Aims: To determine whether MIR146A rs2910164 and MIR128A rs11888095 polymorphisms are associated with early retinal and corneal neurodegenerative changes in pediatric patients with T1D. Methods: A total of 140 T1D children/adolescents underwent spectral domain-optical coherence tomography (SD-OCT) and in vivo confocal microscopy (IVCM) with measurement of retinal and corneal nerve fiber parameters. Risk factors for diabetes complications (diabetes duration, blood pressure, HbA1c) were recorded. Genotyping of rs2910164 and rs1188095 SNPs and genotype-phenotype association analysis were performed. Results: The C allele of rs2910164 in MIR146A was associated with higher values of IVCM parameters and minimum rim width (MRW) of the peripapillary region of optic nerve head measured in the retina, whereas the T allele of rs1188095 in MIR128A was associated with a significant impairment of them. Multiple regression analysis showed that MIR146A and MIR128A polymorphisms were significantly associated with corneal nerve fiber length (beta = 0.225 and - 0.204, respectively) and other IVCM parameters, independently from age, diabetes duration, HbA1c and systolic blood pressure percentile. Similar results were found for MRW (beta = 0.213 and - 0.286, respectively). Conclusions: These results provide new insight into the genetic predisposition to DN showing that two polymorphisms in MIR146A and MIR128A genes could significantly contribute to the development of early ocular preclinical signs of DN
Impact of CFTR Modulators on Beta-Cell Function in Children and Young Adults with Cystic Fibrosis
Background: To date, no consistent data are available on the possible impact of CFTR modulators on glucose metabolism. The aim of this study was to test the hypothesis that treatment with CFTR modulators is associated with an improvement in the key direct determinants of glucose regulation in children and young adults affected by Cystic Fibrosis (CF). Methods: In this study, 21 CF patients aged 10–25 underwent oral glucose tolerance test (OGTT) before and after 12–18 months of treatment with Lumacaftor/Ivacaftor or Elexacaftor-Ivacaftor-Tezacaftor. β-cell function (i.e., first and second phase of insulin secretion measured as derivative and proportional control, respectively) and insulin clearance were estimated by OGTT mathematical modelling. Insulin sensitivity was estimated by the Oral Glucose Sensitivity Index (OGIS). The dynamic interplay between β-cell function, insulin clearance and insulin sensitivity was analysed by vector plots of glucose-stimulated insulin bioavailability vs. insulin sensitivity. Results: No changes in glucose tolerance occurred after either treatment, whereas a significant improvement in pulmonary function and chronic bacterial infection was observed. Beta cell function and insulin clearance did not change in both treatment groups. Insulin sensitivity worsened in the Lumacaftor/Ivacaftor group. The analysis of vector plots confirmed that glucose regulation was stable in both groups. Conclusions: Treatment of CF patients with CFTR modulators does not significantly ameliorate glucose homeostasis and/or any of its direct determinants
Simulation of Europa's water plume
Plumes on Europa would be extremely interesting science and mission targets, particularly due to the unique opportunity to obtain direct information on the subsurface composition, thereby addressing Europa's potential habitability. The existence of water plume on the Jupiter's moon Europa has been long speculated until the recent discover. HST imaged surpluses of hydrogen Lyman alpha and oxygen emissions above the southern hemisphere in December 2012 that are consistent with two 200 km high plumes of water vapor (Roth et al. 2013). In previous works ballistic cryovolcanism has been considered and modeled as a possible mechanism for the formation of low-albedo features on Europa's surface (Fagents et al. 2000). Our simulation agrees with the model of Fagents et al. (2000) and consists of icy particles that follow ballistic trajectories. The goal of such an analysis is to define the height, the distribution and the extension of the icy particles falling on the moon's surface as well as the thickness of the deposited layer. We expect to observe high albedo regions in contrast with the background albedo of Europa surface since we consider that material falling after a cryovolcanic plume consists of snow. In order to understand if this phenomenon is detectable we convert the particles deposit in a pixel image of albedo data. We consider also the limb view of the plume because, even if this detection requires optimal viewing geometry, it is easier detectable in principle against sky. Furthermore, we are studying the loss rates due to impact electron dissociation and ionization to understand how these reactions decrease the intensity of the phenomenon. We expect to obtain constraints on imaging requirements necessary to detect potential plumes that could be useful for ESA's JUICE mission, and in particular for the JANUS camera (Palumbo et al. 2014)
Calibration activities on the BepiColombo High-Resolution Channel (HRIC) of SIMBIO-SYS instrument
HRIC (High Resolution Imaging Channel) is the high resolution channel of the SIMBIO-SYS instrument on- board the ESA BepiColombo Mission. Calibration activities were performed at SelexES premises in spring- summer 2014 in order to check for Channel performances (radiometric performances, quality image and geometrical performances) and to obtain data necessary to setup a calibration pipeline necessary to process the raw images acquired by the channel when in operative scenario
BC-SIM-TR-005 SIMBIO-SYS NECP Test Report
This document will briefly report the results of the tests performed during the Near Earth Commissioning Phase (NECP)
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