943 research outputs found

    At what age should screening mammography be recommended for Asian women?

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    Although regular screening mammography has been suggested to be associated with improvements in the relative survival of breast cancer in recent years, the appropriate age to start screening mammography remains controversial. In November 2009, the United States Preventive Service Task Force published updated guidelines for breast cancer, which no longer support routine screening mammography for women aged 40–49 years, but instead, defer the choice of screening in that age group to the patient and physician. The age to begin screening differs between guidelines, including those from the Task Force, the American Cancer Society and the World Health Organization. It remains unclear how this discrepancy impacts patient survival, especially among certain subpopulations. Although the biological characteristics of breast cancer and peak age of incidence differ among different ethnic populations, there have been few reports that evaluate the starting age for screening mammography based on ethnicity. Here, we discuss the benefits and harm of screening mammography in the fifth decade, and re-evaluate the starting age for screening mammography taking ethnicity into account, focusing on the Asian population. Breast cancer incidence peaked in the fifth decade in Asian women, which has been thought to be due to a combination of biological and environmental factors. Previous reports suggest that Asian women in their 40s may receive more benefit and less harm from screening mammography than the age-matched non-Asian US population. Therefore, starting screening mammography at age 40 may be beneficial for women of Asian ethnicity in well-resourced countries, such as Japanese women who reside in Japan

    Anomalous rotational-alignment in N=Z nuclei and residual neutron-proton interaction

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    Recent experiments have demonstrated that the rotational-alignment for the N=ZN=Z nuclei in the mass-80 region is considerably delayed as compared to the neighboring N≠ZN \ne Z nuclei. We investigate whether this observation can be understood by a known component of nuclear residual interactions. It is shown that the quadrupole-pairing interaction, which explains many of the delays known in rare-earth nuclei, does not produce the substantial delay observed for these N=ZN=Z nuclei. However, the residual neutron-proton interaction which is conjectured to be relevant for N=ZN=Z nuclei is shown to be quite important in explaining the new experimental data.Comment: 4 pages, 3 figures, final version accepted by Phys. Rev. C as a Rapid Communicatio

    Risk stratification for progression of IgA nephropathy using a decision tree induction algorithm

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    Background. Immunoglobulin A nephropathy (IgAN) is the most common form of glomerulonephritis, and many patients are at risk of at least slow progression. However, prediction of the renal outcome in individual patients remains difficult
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