Finite-mass helium atoms. ii- the 23p state plus

Energy states of helium isoelectronic series investigated by 50-term variational wave function with two nonlinear parameter

Disposable cartridge based platform for real-time detection of single viruses in solution

Label-free imaging of viruses and nanoparticles directly in complex solutions is important for virology, vaccine research, and rapid diagnostics. These fields would all benefit from tools that allow for more rapid and sensitive characterization of viruses. Traditionally, light microscopy has been used in laboratories for detection of parasites, fungi, and bacteria for both research and clinical diagnosis because it is portable and simple to use. However, virus particles typically cannot be explored using light microscopy without the use of secondary labels due to their small size and low contrast. Characterization and detection of virus particles therefore rely on more complex approaches such as electron microscopy, ELISA, or plaque assay. These approaches require a significant level of expertise, purification of the virus from its natural environment, and often offer indirect verification of the virus presence. A successful virus visualization technique should be rapid, sensitive, and inexpensive, while needing minimal sample preparation or user expertise. We have developed a disposable cartridge based platform for real-time, sensitive, and label free visualization of viruses and nanoparticles directly in complex solutions such as serum. To create this platform we combined an interference reflectance imaging technique (SP-IRIS) with a sealable microfluidic cartridge. Through empirical testing and numeric modelling, the cartridge parameters were optimized and a flow rate of ~3 µL/min was established as optimal. A complex 2-dimensional paper based capillary pump was incorporated into the polymer cartridge to achieve a constant flow rate. Using this platform we were able to reliably show virus detection in a 20 minute experiment. We demonstrate sensitivity comparable to laboratory-based assays such as ELISA and plaque assay, and equal or better sensitivity compared to paper based rapid diagnostic tests. These results display a platform technology that is capable of rapid multiplexed detection and visualization of viruses and nanoparticles directly in solution. This disposable cartridge based platform represents a new approach for sample-to-answer label-free detection and visualization of viruses and nanoparticles. This technology has the potential to enable rapid and high-throughput investigation of virus particle morphology, as well as be used as a rapid point-of-care diagnostic tool where imaging viruses directly in biological samples would be valuable

Towards a Jurisprudence (and Pedagogy) of Access: A Reflection on 25 Years of the Public Interest Practicum

The Public Interest Practicum (PIP), a course at the University of Georgia School of Law, fosters awareness among law students of the demand for access to justice. For more than 25 years, PIP has served many purposes: to explore a street level jurisprudence; to challenge students’ professional identities; to generate new models of clinical legal education; to inculcate the habit of public service; and to help individuals with legal problems. Through its many iterations, PIP has consistently exposed future lawyers to ways of helping those in need. This reflection traces the history of PIP as a course, contextualizes it within several modern movements, and assesses it as a way to teach the value of access to justice to law students

Towards a Jurisprudence (and Pedagogy) of Access: A Reflection on 25 Years of the Public Interest Practicum

The Public Interest Practicum (PIP), a course at the University of Georgia School of Law, fosters awareness among law students of the demand for access to justice. For more than 25 years, PIP has served many purposes: to explore a street level jurisprudence; to challenge students’ professional identities; to generate new models of clinical legal education; to inculcate the habit of public service; and to help individuals with legal problems. Through its many iterations, PIP has consistently exposed future lawyers to ways of helping those in need. This reflection traces the history of PIP as a course, contextualizes it within several modern movements, and assesses it as a way to teach the value of access to justice to law students

Gesture analysis for physics education researchers

Systematic observations of student gestures can not only fill in gaps in students' verbal expressions, but can also offer valuable information about student ideas, including their source, their novelty to the speaker, and their construction in real time. This paper provides a review of the research in gesture analysis that is most relevant to physics education researchers and illustrates gesture analysis for the purpose of better understanding student thinking about physics.Comment: 14 page

Overcoming Innocents’ Naiveté: Pre‐interrogation Decision‐making Among Innocent Suspects

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/133623/1/bsl2247.pd