745 research outputs found

    Tiny Groups Tackle Byzantine Adversaries

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    A popular technique for tolerating malicious faults in open distributed systems is to establish small groups of participants, each of which has a non-faulty majority. These groups are used as building blocks to design attack-resistant algorithms. Despite over a decade of active research, current constructions require group sizes of O(logn)O(\log n), where nn is the number of participants in the system. This group size is important since communication and state costs scale polynomially with this parameter. Given the stubbornness of this logarithmic barrier, a natural question is whether better bounds are possible. Here, we consider an attacker that controls a constant fraction of the total computational resources in the system. By leveraging proof-of-work (PoW), we demonstrate how to reduce the group size exponentially to O(loglogn)O(\log\log n) while maintaining strong security guarantees. This reduction in group size yields a significant improvement in communication and state costs.Comment: This work is supported by the National Science Foundation grant CCF 1613772 and a C Spire Research Gif

    Arbuscular mycorrhizal fungi altered the hypericin, pseudohypericin, and hyperforin content in flowers of Hypericum perforatum grown under contrasting P availability in a highly organic substrate

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    St. John’s Wort (Hypericum perforatum) is a perennial herb able to produce water-soluble active ingredients (a.i.), mostly in flowers, with a wide range of medicinal and biotechnological uses. However, information about the ability of arbuscular mycorrhizal fungi (AMF) to affect its biomass accumulation, flower production, and concentration of a.i. under contrasting nutrient availability is still scarce. In the present experiment, we evaluated the role of AMF on growth, flower production, and concentration of bioactive secondary metabolites (hypericin, pseudohypericin, and hyperforin) of H. perforatum under contrasting P availability. AMF stimulated the production of aboveground biomass under low P conditions and increased the production of root biomass. AMF almost halved the number of flowers per plant by means of a reduction of the number of flower-bearing stems per plant under high P availability and through a lower number of flowers per stem in the low-P treatment. Flower hyperforin concentration was 17.5% lower in mycorrhizal than in non-mycorrhizal plants. On the contrary, pseudohypericin and hypericin concentrations increased by 166.8 and 279.2%, respectively, with AMF under low P availability, whereas no effect of AMF was found under high P availability. These results have implications for modulating the secondary metabolite production of H. perforatum. However, further studies are needed to evaluate the competition for photosynthates between AMF and flowers at different nutrient availabilities for both plant and AM fungus

    Uncompleted Emergency Department Care (UEDC): A 5-year population-based study in the Veneto Region, Italy

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    Introduction: Uncompleted visits to emergency departments (UEDC) are a patient safety concern. The purpose of this study was to investigate risk factors for UEDC, describing not only the sociodemographic characteristics of patients who left against medical advice (AMA) and those who left without being seen (LWBS), but also the characteristics of their access to the emergency department (ED) and of the hospital structure. Methods: This was a cross sectional study on anonymized administrative data in a population-based ED database. Results: A total of 9,147,415 patients attended EDs in the Veneto Region from 2011 to 2015. The UEDC rate was 28.7\u2030, with a slightly higher rate of AMA than of LWBS (15.3\u2030 vs 13.4\u2030). Age, sex, citizenship, and residence were sociodemographic factors associated with UEDC, and so were certain characteristics of access, such as mode of admission, type of referral, emergency level, waiting time before being seen, and type of medical issue (trauma or other). Some characteristics of the hospital structure, such as the type of hospital and the volume of patients managed, could also be associated with UEDC. Conclusion: Cases of UEDC, which may involve patients who leave AMA and those who LWBS, differ considerably from other cases managed at the ED. The present findings are important for the purpose of planning and staffing health services. Decision-makers should identify and target the factors associated with UEDC to minimize walkouts from public hospital EDs

    Validating the regional estimates of changes in soil organic carbon by using the data from paired-sites: the case study of Mediterranean arable lands

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    BACKGROUND: Legacy data are unique occasions for estimating soil organic carbon (SOC) concentration changes and spatial variability, but their use showed limitations due to the sampling schemes adopted and improvements may be needed in the analysis methodologies. When SOC changes is estimated with legacy data, the use of soil samples collected in different plots (i.e., non-paired data) may lead to biased results. In the present work, N = 302 georeferenced soil samples were selected from a regional (Sicily, south of Italy) soil database. An operational sampling approach was developed to spot SOC concentration changes from 1994 to 2017 in the same plots at the 0-30 cm soil depth and tested. RESULTS: The measurements were conducted after computing the minimum number of samples needed to have a reliable estimate of SOC variation after 23 years. By applying an effect size based methodology, 30 out of 302 sites were resampled in 2017 to achieve a power of 80%, and an α = 0.05. A Wilcoxon test applied to the variation of SOC from 1994 to 2017 suggested that there was not a statistical difference in SOC concentration after 23 years (Z = - 0.556; 2-tailed asymptotic significance = 0.578). In particular, only 40% of resampled sites showed a higher SOC concentration than in 2017. CONCLUSIONS: This finding contrasts with a previous SOC concentration increase that was found in 2008 (75.8% increase when estimated as differences of 2 models built with non-paired data), when compared to 1994 observed data (Z = - 9.119; 2-tailed asymptotic significance < 0.001). This suggests that the use of legacy data to estimate SOC concentration dynamics requires soil resampling in the same locations to overcome the stochastic model errors. Further experiment is needed to identify the percentage of the sites to resample in order to align two legacy datasets in the same area

    Feeding emitters for microirrigation with a digestate liquid fraction up to 25% dilution did not reduce their performance

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    Irrigation with wastewater can strongly contribute to the reduction of water abstraction in agriculture with an especial interest in arid and semiarid areas. However, its use can have drawbacks to both soil and micro-irrigation systems, especially when the total solids in the wastewater are high, such as in digestate liquid fractions (DLF) from plant material. The aim of this study was thus to evaluate the performances of a serpentine shaped micro-emitter injected with a hydrocyclone filtered DLF (HF-DLF) from corn + barley biomass and evaluate the traits of the liquid released within a 8-h irrigation cycle. HF-DLF was injected at 10%, 25%, and 50% dilution compared to tap water (at pH = 7.84) and the system performances were measured. No clogging was found, which likely depended on both the shape of the emitter and the high-pressure head (200 kPa). HF-DLF dilution at 10%, 25%, and 50% consisted in +1.9%, +3.5, and -4.9% amount of liquid released compared to the control. Fluid temperature during irrigation (from 9:00 to 17:00) did not explain the difference in the released amounts of liquid. In 10% HF-DLF % and 25% HF-DLF, a pH difference of + 0.321 ± 0.014 pH units compared to the control was found, and such difference was constant for both dilutions and at increasing the time. In contrast, 50% HF-DLF increased pH by around a half point and such difference increased with time. Similar differences among treatments were found for the total solids in the liquid. These results indicate that 50% HF-DLF was accumulating materials in the serpentine. These results suggest that a low diluted HF-DLF could directly be injected in irrigation systems with few drawbacks for the irrigation system and contribute to water conservation since such wastewater are available from the late spring to the early fall, when water requirements are high
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