Road-traffic pollution and asthma – using modelled exposure assessment for routine public health surveillance

Asthma is a common disease and appears to be increasing in prevalence. There is evidence linking air pollution, including that from road-traffic, with asthma. Road traffic is also on the increase. Routine surveillance of the impact of road-traffic pollution on asthma, and other diseases, would be useful in informing local and national government policy in terms of managing the environmental health risk. Several methods for exposure assessment have been used in studies examining the association between asthma and road traffic pollution. These include comparing asthma prevalence in areas designated as high and low pollution areas, using distance from main roads as a proxy for exposure to road traffic pollution, using traffic counts to estimate exposure, using vehicular miles travelled and using modelling techniques. Although there are limitations to all these methods, the modelling approach has the advantage of incorporating several variables and may be used for prospective health impact assessment. The modelling approach is already in routine use in the United Kingdom in support of the government's strategy for air quality management. Combining information from such models with routinely collected health data would form the basis of a routine public health surveillance system. Such a system would facilitate prospective health impact assessment, enabling policy decisions concerned with road-traffic to be made with knowledge of the potential implications. It would also allow systematic monitoring of the health impacts when the policy decisions and plans have been implemented

A Convertible Poultry Shelter House

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The Stellar Masses and Star Formation Histories of Galaxies at z ≈ 6: Constraints from Spitzer Observations in the Great Observatories Origins Deep Survey

Using the deep Spitzer Infrared Array Camera (IRAC) observations of the Great Observatories Origins Deep Survey (GOODS), we study the stellar masses and star formation histories of galaxies at z approx 6 based on the i_(775)-band dropout sample selected from the GOODS fields. In total, we derive stellar masses for 53 i_(775)-band dropouts that have robust IRAC detections. These galaxies have typical stellar masses of ~10^(10) M_⊙ and typical ages of a couple of hundred million years, consistent with earlier results based on a smaller sample of z ≈ 6 galaxies. The existence of such massive galaxies at z ≈ 6 can be explained by at least one set of N-body simulations of the hierarchical paradigm. We also study 79 i_(775)-band dropouts that are invisible in the IRAC data and find that they are typically less massive by a factor of 10. These galaxies are much bluer than those detected by the IRAC, indicating that their luminosities are dominated by stellar populations with ages ≾ 40 Myr. Based on our mass estimates, we derive a lower limit to the global stellar mass density at z ≈ 6, which is 1.1-6.7 × 10^6 M_⊙ Mpc^(-3). The prospect of detecting the progenitors of the most massive galaxies at yet higher redshifts is explored. We also investigate the implication of our results for reionization and find that the progenitors of the galaxies comparable to those in our sample, even in the most optimized (probably unrealistic) scenario, cannot sustain the reionization for a period longer than ~2 Myr. Thus most of the photons required for reionization must have been provided by other sources, such as the progenitors of the dwarf galaxies that are far below our current detection capability

On the accretion origin of a vast extended stellar disk around the Andromeda galaxy

We present the discovery of an inhomogenous, low-surface brightness, extended disk-like structure around the Andromeda galaxy (M31) based on a large kinematic survey of more than 2800 stars with the Keck/DEIMOS spectrograph. The stellar structure spans radii from 15 kpc out to ~40 kpc, with detections out to R ~ 70 kpc. The constituent stars lag the expected velocity of circular orbits in the plane of the M31 disk by ~40 kms and have a velocity dispersion of ~30 kms. The color range on the upper RGB shows a large spread indicative of a population with a significant range of metallicity. The mean metallicity of the population, measured from Ca II equivalent widths, is [Fe/H] = -0.9 +/- 0.2. The morphology of the structure is irregular at large radii, and shows a wealth of substructures which must be transitory in nature, and are almost certainly tidal debris. The presence of these substructures indicates that the global entity was formed by accretion. This extended disk follows smoothly on from the central parts of M31 disk with an exponential density law of scale-length of 5.1 +/- 0.1 kpc, similar to that of the bright inner disk. The population possesses similar kinematic and abundance properties over the entire region where it is detected in the survey. We estimate that the structure accounts for approximately 10% of the total luminosity of the M31 disk, and given the huge scale, contains ~30% of the total disk angular momentum. This finding indicates that at least some galactic stellar disks are vastly larger than previously thought and are formed, at least in their outer regions, primarily by accretion. [abridged]Comment: 20 pages, 30 figures, ApJ submitte

On a model mechanism for the spatial patterning of teeth primordia in the Alligator

We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator,Alligator mississippiensis. Detailed embryological studies by Westergaard & Ferguson (1986, 1987, 1990) show that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a reaction-diffusion mechanism, which crucially includes domain growth. The model can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw ofA. mississippiensis. The results for the precise spatio-temporal sequence compare well with detailed developmental experiments