An analytical model of prominence dynamics

Solar prominences are magnetic structures incarcerating cool and dense gas in an otherwise hot solar corona. Prominences can be categorized as quiescent and active. Their origin and the presence of cool gas (~$10^4$K) within the hot (~$10^6$K) solar corona remains poorly understood. The structure and dynamics of solar prominences was investigated in a large number of observational and theoretical (both analytical and numerical) studies. In this paper, an analytic model of quiescent solar prominence is developed and used to demonstrate that the prominence velocity increases exponentially, which means that some gas falls downward towards the solar surface, and that Alfven waves are naturally present in the solar prominences. These theoretical predictions are consistent with the current observational data of solar quiescent prominences.Comment: Update Final Journal Print Version along with other Metadat

The Schwinger SU(3) construction - I: Multiplicity problem and relation to induced representations

The Schwinger oscillator operator representation of SU(3) is analysed with particular reference to the problem of multiplicity of irreducible representations. It is shown that with the use of an $Sp(2,R)$ unitary representation commuting with the SU(3) representation, the infinity of occurrences of each SU(3) irreducible representation can be handled in complete detail. A natural `generating representation' for SU(3), containing each irreducible representation exactly once, is identified within a subspace of the Schwinger construction; and this is shown to be equivalent to an induced representation of SU(3).Comment: Latex, 25 page

Process Personalization Framework for Service-Driven Enterprises

Service functions and service activities are integral part of enterprises. Although technologies have improved for developing service functions, errors persist in service activities. Noted computer scientist Ramamoorthy describes personalization, customization, and humanization of service functions as an effective approach for reducing error in service activities. This paper argues that current personalization approaches does not effectively address the entire spectrum of service functions. The proposed personalization framework can advance current state of personalization through enabling tools as services and services as tools. We discuss the framework utilizing biological research as a service-driven enterprise example. The proposed framework is based on our enterprise process personalization patent

Arecoline induced disruption of expression and localization of the tight junctional protein ZO-1 is dependent on the HER 2 expression in human endometrial Ishikawa cells

<p>Abstract</p> <p>Background</p> <p>Approximately 600 million people chew Betel nut, making this practice the fourth most popular oral habit in the world. Arecoline, the major alkaloid present in betel nut is one of the causative agents for precancerous lesions and several cancers of mouth among those who chew betel nut. Arecoline can be detected in the human embryonic tissue and is correlated to low birth weight of newborns whose mothers chew betel nut during pregnancy, suggesting that arecoline can induce many systemic effects. However, few reports exist as to the effects of arecoline in human tissues other than oral cancer cell lines. Furthermore, in any system, virtually nothing is known about the cellular effects of arecoline treatment on membrane associated signaling components of human cancer cells.</p> <p>Results</p> <p>Using the human Ishikawa endometrial cancer cell line, we investigated the effects of arecoline on expression, localization and functional connections between the ZO-1 tight junction protein and the HER2 EGF receptor family member. Treatment of Ishikawa cells with arecoline coordinately down-regulated expression of both ZO-1 and HER2 protein and transcripts in a dose dependent manner. Biochemical fractionation of cells as well as indirect immunofluorescence revealed that arecoline disrupted the localization of ZO-1 to the junctional complex at the cell periphery. Compared to control transfected cells, ectopic expression of exogenous HER2 prevented the arecoline mediated down-regulation of ZO-1 expression and restored the localization of ZO-1 to the cell periphery. Furthermore, treatment with dexamethasone, a synthetic glucocorticoid reported to up-regulate expression of HER2 in Ishikawa cells, precluded arecoline from down-regulating ZO-1 expression and disrupting ZO-1 localization.</p> <p>Conclusion</p> <p>Arecoline is known to induce precancerous lesions and cancer in the oral cavity of betel nut users. The arecoline down-regulation of ZO-1 expression and subcellular distribution suggests that arecoline potentially disrupts cell-cell interactions mediated by ZO-1, which may play a role in arecoline-mediated carcinogenesis. Furthermore, our study has uncovered the dependency of ZO-1 localization and expression on HER2 expression, which has therefore established a new cellular link between HER2 mediated signaling and apical junction formation involving ZO-1.</p

A handy tool for forecasting population to aid estimation of water demand

1587-1592Estimation of demographic variations for societal or infrastructural development policies requires accurate prediction of futuristic population for a given locality. Economic viability as well as sustainability at large, of the engineering designs in urban development activities depend on the variations in projected populations for a given design period. Considering the uncertainties in existing calculation practices to derive an average value, present study offers a computationally efficient program capable of forecasting the future population based on the existing past population data using three well-known population forecasting methods, namely, arithmetic increase method, geometric increase method and incremental increase method. The results proved that when compared to manual calculation, the predictions were accurate, precise and computationally efficient. This user-friendly tool will be highly beneficial for various service providers where population forecasting is inevitable. The robustness of the computer code has been demonstrated using six decades of real time census data of Coimbatore city