310 research outputs found
Electronic structure near the 1/8-anomaly in La-based cuprates
We report an angle resolved photoemission study of the electronic structure
of the pseudogap state in \NdLSCO ( K). Two opposite dispersing Fermi
arcs are the main result of this study. The several scenarios that can explain
this observation are discussed.Comment: A high-resolution version can be found at
http://lns.web.psi.ch/lns/download/Pockets/arXiv.pd
Serial extraction of endosperm drillings (SEED)—A method for detecting transgenes and proteins in single viable maize kernels
We have developed a method for detecting a transgene and its protein product in maize endosperm that allows the kernel to be germinated after analysis. This technique could be highly useful for several monocots and dicots. Our method involves first sampling the endosperm with a hand-held rotary grinder so that the embryo is preserved and capable of germination. This tissue is then serially extracted, first with SDS-PAGE sample buffer to extract proteins, then with an aqueous buffer to extract DNA. The product of the transgene can be detected in the first extract by SDS-PAGE with visualization by total protein staining or immuno-blot detection. The second extract can be purified and used as template DNA in PCR reactions to detect the transgene. This method is particularly useful for screening transgenic kernels in breeding experiments and testing for gene silencing in kernels
The excitation spectrum for weakly interacting bosons in a trap
We investigate the low-energy excitation spectrum of a Bose gas confined in a
trap, with weak long-range repulsive interactions. In particular, we prove that
the spectrum can be described in terms of the eigenvalues of an effective
one-particle operator, as predicted by the Bogoliubov approximation.Comment: LaTeX, 32 page
Saliva urea nitrogen dipsticks to predict acute kidney injury in Malawian trauma patients
Background: Many low-resource settings have limited access to serum creatinine tests necessary for kidney disease identification. Among Malawian patients who are hospitalized after trauma, we evaluated the use of point-of-care saliva urea nitrogen (SUN) dipsticks to predict acute kidney injury (AKI).
Methods: In a nested prospective cohort study, we enrolled hospitalized acute trauma patients aged ≥6 months to evaluate AKI (defined by KDIGO criteria) and the test characteristics of SUN to predict AKI.
Results: Among 335 participants (approximately three-quarters able to expectorate and 34% aged ≤18 years), 12.5% (n = 42) developed AKI. At a SUN threshold of ≥40 mg/dL, a positive dipstick test was specific (99.3%) but insensitive (14.3%) in predicting AKI, with a positive predictive value of 75% and negative predictive value of 89%. At this threshold, 2.4% of participants were dipstick-positive (SUN+), and 75% of those had AKI. Reducing the SUN threshold to ≥30 mg/dL increased participants who were SUN+ to 5.0% (n = 16) but also increased the false positive rate and missed 79% (n = 33) of AKI cases. Stratified results showed better performance among adults than children and similar results when comparing participants who could and could not expectorate. There was moderate correlation between categorized BUN values and SUN (r = 0.53) but less agreement (weighted kappa 0.27; 95% CI 0.17–0.37).
Conclusions: SUN dipstick testing has good specificity and negative predictive value for ruling out AKI, but poor sensitivity. We found similar results among those who could or could not expectorate a saliva sample
The dose–response effect of insulin sensitivity on albuminuria in children according to diabetes type
Insulin resistance is associated with microalbuminuria among youth with diabetes mellitus. We sought to determine the dose-response effect of insulin sensitivity (IS) on the magnitude of albuminuria and whether there is a threshold below which urine albumin excretion increases
Field-induced soft-mode quantum phase transition in LaSrCuO
Inelastic neutron-scattering experiments on the high-temperature
superconductor LaSrCuO reveal a magnetic excitation
gap that decreases continuously upon application of a magnetic field
perpendicular to the CuO planes. The gap vanishes at the critical field
required to induce long-range incommensurate antiferromagnetic order, providing
compelling evidence for a field-induced soft-mode driven quantum phase
transition
Veritas et Vanitas
A journal of creative nonfiction produced by students at the Marion campus of The Ohio State University with contributions from the students and faculty at the Marion campus of The Ohio State University and Marion Technical College
Supervised selective kernel fusion for membrane protein prediction
Membrane protein prediction is a significant classification problem, requiring the integration of data derived from different sources such as protein sequences, gene expression, protein interactions etc. A generalized probabilistic approach for combining different data sources via supervised selective kernel fusion was proposed in our previous papers. It includes, as particular cases, SVM, Lasso SVM, Elastic Net SVM and others. In this paper we apply a further instantiation of this approach, the Supervised Selective Support Kernel SVM and demonstrate that the proposed approach achieves the top-rank position among the selective kernel fusion variants on benchmark data for membrane protein prediction. The method differs from the previous approaches in that it naturally derives a subset of “support kernels” (analogous to support objects within SVMs), thereby allowing the memory-efficient exclusion of significant numbers of irrelevant kernel matrixes from a decision rule in a manner particularly suited to membrane protein prediction
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