Association of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and high-grade undifferentiated endometrial sarcoma. a case report

Endometriosis is a chronic disease that affects women of reproductive age. Malignant transformation in endometriosis is considered to be an unusual event, only occurring in 0.7-0.1% of cases. However the association between endometriosis and endometrial cancer is not well defined. Also in literature, rare cases of uterine sarcoma, about 3% of all uterine malignancies, associated with endometriosis have been reported. The authors report a case of a 47-years-old Italian woman with histologic diagnosis of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and undifferentiated endometrial sarcoma. Therefore there have been few studies addressing the relationship between endometrial stromal sarcomas (ESS), and endometriosis. Novel scientific findings are necessary to investigate a possible common pathway and an effective treatment, although complete tumor resection can reduce the recurrence rate

Ovarian endometrioid adenocarcinoma diagnosed in pregnancy. a case report

The prevalence of adnexal masses pregnancy is about 0.19-8.8%. The malignancy rate is around 1-6%, and indeed most cases are benign masses. During pregnancy adnexal masses should be accurately evaluated to identify the patients who need surgery from those who need a 'wait-and-see' strategy. The authors report a case of 36-year-old woman (gravida 2, para 2, two vaginal deliveries) referred to the Gynecologic Department with diagnosis of endometrioid ovarian adenocarcinoma. The patient underwent laparotomic surgery with left salpingo-oophorectomy, total hysterectomy, pelvic and para-aortic lymphadenectomy, and peritoneal washing for optimal surgery staging. No ascites or residual tumour in the abdominal cavity were found macroscopically. Histopathology was negative for residual ovarian cancer. Currently the treatment and the management of ovarian cancer are not well established because scientific evidence is limited

Design-thinking, making, and innovating: Fresh tools for the physician\u27s toolbox

Medical school education should foster creativity by enabling students to become \u27makers\u27 who prototype and design. Healthcare professionals and students experience pain points on a daily basis, but are not given the tools, training, or opportunity to help solve them in new, potentially better ways. The student physician of the future will learn these skills through collaborative workshops and having dedicated \u27innovation time.\u27 This pre-clinical curriculum would incorporate skills centered on (1) Digital Technology and Small Electronics (DTSE), (2) Textiles and Medical Materials (TMM), and (3) Rapid Prototyping Technologies (RPT). Complemented by an on-campus makerspace, students will be able to prototype and iterate on their ideas in a fun and accessible space. Designing and making among and between patients and healthcare professionals would change the current dynamic of medical education, empowering students to solve problems in healthcare even at an early stage in their career. By doing so, they will gain empathy, problem-solving abilities, and communication skills that will extend into clinical practice. Our proposed curriculum will equip medical students with the skills, passion, and curiosity to impact the future of healthcare

Cosmological versus Intrinsic: The Correlation between Intensity and the Peak of the nu F_nu Spectrum of Gamma Ray Bursts

We present results of correlation studies, examining the association between the peak of the nu F_nu spectrum of gamma ray bursts, E_p, with the burst's energy fluence and photon peak flux. We discuss methods to account for data truncation in E_p and fluence or flux when performing the correlation analyses. However, because bursts near the detector threshold are not usually able to provide reliable spectral parameters, we focus on results for the brightest bursts in which we can better understand the selection effects relevant to E_p and burst strength. We find that there is a strong correlation between total fluence and E_p. We discuss these results in terms of both cosmological and intrinsic effects. In particular, we show that for realistic distributions of the burst parameters, cosmological expansion alone cannot account for the correlation between E_p and total fluence; the observed correlation is likely a result of an intrinsic relation between the burst rest-frame peak energy and the total radiated energy. We investigate this latter scenario in the context of synchrotron radiation from external and internal shock models of GRBs. We find that the internal shock model is consistent with our interpretation of the correlation, while the external shock model cannot easily explain this intrinsic relation between peak energy and burst radiated energy.Comment: 23 pages, including 8 postscript figures. Submitted to Ap

The BATSE Gamma-Ray Burst Spectral Catalog. I. High Time Resolution Spectroscopy of Bright Bursts using High Energy Resolution Data

This is the first in a series of gamma-ray burst spectroscopy catalogs from the Burst And Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory, each covering a different aspect of burst phenomenology. In this paper, we present time-sequences of spectral fit parameters for 156 bursts selected for either their high peak flux or fluence. All bursts have at least eight spectra in excess of 45 sigma above background and span burst durations from 1.66 to 278 s. Individual spectral accumulations are typically 128 ms long at the peak of the brightest events, but can be as short as 16 ms, depending on the type of data selected. We have used mostly high energy resolution data from the Large Area Detectors, covering an energy range of typically 28 - 1800 keV. The spectral model chosen is from a small empirically-determined set of functions, such as the well-known `GRB' function, that best fits the time-averaged burst spectra. Thus, there are generally three spectral shape parameters available for each of the 5500 total spectra: a low-energy power-law index, a characteristic break energy and possibly a high-energy power-law index. We present the distributions of the observed sets of these parameters and comment on their implications. The complete set of data that accompanies this paper is necessarily large, and thus is archived electronically at: http://www.journals.uchicago.edu/ApJ/journal/.Comment: Accepted for publication: ApJS, 125. 38 pages, 9 figures; supplementary electronic archive to be published by ApJ; available from lead author upon reques

Expanding Respite Care Services to Meet Demand and Increase Organizational Competitiveness

This paper presents the results of student efforts in an undergraduate Capstone course at Molloy University’s School of Business. During the 14-week Spring 2023 semester, these 12 students worked in small teams to address an opportunity presented by a senior executive of The Viscardi Center, a highly regarded 70-year old nonprofit organization based in Albertson (Long Island), New York. To help executives evaluate whether Viscardi could expand its respite care services, students were asked to conduct: (1) research about competitive respite care services/programs; (2) market research with key stakeholders; and, (3) an analysis of financial viability. Students gave Viscardi the “green light,” and delivered their recommendations in three business reports and presentations at the end of the semester. Recommendations were based on industry and organizational research. All recommendations included turn-key implementation plans, projected benefits, potential risks and mitigation efforts, and more. With this collaboration, The Viscardi Center, joins a growing list of repeat Capstone clients which is a testament to the valuable work of our Molloy business students. Capstone is a culminating course required of all Molloy business students in their final year or semester. It involves three mixed methods: the flipped classroom, community engagement, and experiential learning