A precise new KLOE measurement of ∣Fπ∣2|F_\pi|^2 with ISR events and determination of ππ\pi\pi contribution to aμa_\mu for 0.592<Mππ<0.9750.592 < M_{\pi\pi} < 0.975 GeV

The KLOE experiment at the DA$\Phi$NE $\phi$-factory has performed a new precise measurement of the pion form factor using Initial State Radiation events, with photons emitted at small polar angle. Results based on an integrated luminosity of 240 pb$^{-1}$ and extraction of the $\pi\pi$ contribution to $a_\mu$ in the mass range $0.35< M^2_{\pi\pi}<0.95$ GeV$^2$ are presented. The new value of $a^{\pi\pi}_\mu$ has smaller (30%) statistical and systematic error and is consistent with the KLOE published value (confirming the current disagreement between the standard model prediction for $a_\mu$ and the measured value).Comment: 5 pages, proceedings for the CIPANP 2009 conferenc

Investigating Social Exclusion in Late Prehistoric Italy: Preliminary Results of the ‘‘IN or OUT’’ Project (PHASE 1)

This report presents the preliminary results of the ‘‘IN or OUT’’ Project, a collaborative, interdisciplinary effort which aims to investigate social exclusion, marginality and the adoption of anomalous funerary rites in late prehistoric Italy. In particular, this contribution explores the incidence and meaning of practices of ritual marginalisation and funerary deviancy in the region of Veneto between the Bronze Age and the early Iron Age period

Indagini archeometriche su alcuni pesi da telaio dalla 'Cisalpina' protostorica

This paper presents the preliminary results of an archaeometric analysis on 13 loom-weights from some protohistoric and pre-roman settlements of southern Veneto. The artefacts are dated to Final Bronze age and 1st Iron age (Mariconda di Melara, Frattesina, Villamarzana - Rovigo), 6th cent. b.C. (Oppeano - Verona) and 3rd-2nd cent. b.C. (Adria - Rovigo). The oldest artefacts from the Polesine area present an annular shape with sub-rounded or sub-quadrangular sections while those from Adria are bun shaped with a narrower inner hole. As regards the sample from Oppeano, it presents an end-pyramid shape with a small circular hole in the upper side. The minero-petrographic analysis by optical microscopy (OM) and X-ray powder diffraction (XRPD) has been addressed to the compositional characterization of these materials to better understand their technological and functional parameters, as well as to identify possible provenance markers useful to constrain local productions. The study has shown how these loom-weights are produced using mainly local raw materials helpful to create a reference group. The research has put the bases for the setting up of a minero-petrographic database on these type of ceramic class. The analysis could be also extended in future to other previous, contemporaneous as well as Roman sites

Letter: chronic hepatitis C genotype 3 infection - still a hurdle toward a direct-acting anti-viral-induced HCV cure?

Letter: chronic hepatitis C genotype 3 infection – still a hurdle toward a direct-acting anti-viral-induced HCV cur

CHANTI: a Fast and Efficient Charged Particle Veto Detector for the NA62 Experiment at CERN

The design, construction and test of a charged particle detector made of scintillation counters read by Silicon Photomultipliers (SiPM) is described. The detector, which operates in vacuum and is used as a veto counter in the NA62 experiment at CERN, has a single channel time resolution of 1.14 ns, a spatial resolution of ~2.5 mm and an efficiency very close to 1 for penetrating charged particles

Analysis of short-term blood pressure variability in pheochromocytoma/paraganglioma patients

Data on short-term blood pressure variability (BPV), which is a well-established cardiovascular prognostic tool, in pheochromocytoma and paraganglioma (PPGL) patients is still lack and conflicting. We retrospectively evaluated 23 PPGL patients referred to our unit from 2010 to 2019 to analyze 24 h ambulatory blood pressure monitoring (24-h ABPM)-derived markers of short-term BPV, before and after surgical treatment. PPGL diagnosis was assessed according to guidelines and confirmed by histologic examination. The 24-h ABPM-derived markers of short-term BPV included: circadian pressure rhythm; standard deviation (SD) and weighted SD (wSD) of 24-h, daytime, and night-time systolic and diastolic blood pressure (BP); average real variability (ARV) of 24-h, daytime, and night-time systolic and diastolic BP. 7 males and 16 females of 53 ± 18 years old were evaluated. After surgical resection of PPGL we found a significant decrease in 24-h systolic BP ARV (8.8 ± 1.6 vs. 7.6 ± 1.3 mmHg, p &lt; 0.001), in 24-h diastolic BP ARV (7.5 ± 1.6 vs. 6.9 ± 1.4 mmHg, p = 0.031), and in wSD of 24-h diastolic BP (9.7 ± 2.0 vs 8.8 ± 2.1 mmHg, p = 0.050) comparing to baseline measurements. Moreover, baseline 24-h urinary metanephrines significantly correlated with wSD of both 24-h systolic and diastolic BP. Our study highlights as PPGL patients, after proper treatment, show a significant decrease in some short-term BPV markers, which might represent a further cardiovascular risk factor

A prototype large-angle photon veto detector for the P326 experiment at CERN

The P326 experiment at the CERN SPS has been proposed with the purpose of measuring the branching ratio for the decay K^+ \to \pi^+ \nu \bar{\nu} to within 10%. The photon veto system must provide a rejection factor of 10^8 for \pi^0 decays. We have explored two designs for the large-angle veto detectors, one based on scintillating tiles and the other using scintillating fibers. We have constructed a prototype module based on the fiber solution and evaluated its performance using low-energy electron beams from the Frascati Beam-Test Facility. For comparison, we have also tested a tile prototype constructed for the CKM experiment, as well as lead-glass modules from the OPAL electromagnetic barrel calorimeter. We present results on the linearity, energy resolution, and time resolution obtained with the fiber prototype, and compare the detection efficiency for electrons obtained with all three instruments.Comment: 8 pages, 9 figures, 2 tables. Presented at the 2007 IEEE Nuclear Science Symposium, Honolulu HI, USA, 28 October - 3 November 200

Muon Radiography Investigations in Boreholes with a Newly Designed Cylindrical Detector

Muons are constantly produced in cosmic-rays and reach the Earth surface with a flux of about 160 particles per second per square meter. The abundance of muons with respect to other cosmic particles and their capability to cross dense materials with low absorption rate allow them to be exploited for large scale geological or human-made object imaging. Muon radiography is based on similar principles as X-ray radiography, measuring the surviving rate of muons escaping the target and relating it to the mass distribution inside the object. In the course of decades, after the first application in 1955, the methodology has been applied in several different fields. Muography allows us to measure the internal density distribution of the investigated object, or to simply highlight the presence of void regions by observing any excess of muons. Most of these applications require the detector to be installed below the rock being probed. In case that possible installation sites are not easily accessible by people, common instrumentation cannot be installed. A novel borehole cylindrical detector for muon radiography has been recently developed to deal with these conditions. It has been realized with a cylindrical geometry to fit typical borehole dimensions. Its design maximizes the geometrical acceptance, minimizing the dead spaces by the use of arc-shaped scintillators. The details of the construction and preliminary results of the first usage are described in this paper. © 2022 by the authors

Computational approaches to shed light on molecular mechanisms in biological processes

Computational approaches based on Molecular Dynamics simulations, Quantum Mechanical methods and 3D Quantitative Structure-Activity Relationships were employed by computational chemistry groups at the University of Milano-Bicocca to study biological processes at the molecular level. The paper reports the methodologies adopted and the results obtained on Aryl hydrocarbon Receptor and homologous PAS proteins mechanisms, the properties of prion protein peptides, the reaction pathway of hydrogenase and peroxidase enzymes and the defibrillogenic activity of tetracyclines. © Springer-Verlag 2007

The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori

We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4\u20135 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease