2,882 research outputs found

    On characters of Chevalley groups vanishing at the non-semisimple elements

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    Let G be a finite simple group of Lie type. In this paper we study characters of G that vanish at the non-semisimple elements and whose degree is equal to the order of a maximal unipotent subgroup of G. Such characters can be viewed as a natural generalization of the Steinberg character. For groups G of small rank we also determine the characters of this degree vanishing only at the non-identity unipotent elements.Comment: Dedicated to Lino Di Martino on the occasion of his 65th birthda

    PI3Kinase signaling in glioblastoma

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    Glioblastoma (GBM) is the most common primary tumor of the CNS in the adult. It is characterized by exponential growth and diffuse invasiveness. Among many different genetic alterations in GBM, e.g., mutations of PTEN, EGFR, p16/p19 and p53 and their impact on aberrant signaling have been thoroughly characterized. A major barrier to develop a common therapeutic strategy is founded on the fact that each tumor has its individual genetic fingerprint. Nonetheless, the PI3K pathway may represent a common therapeutic target to most GBM due to its central position in the signaling cascade affecting proliferation, apoptosis and migration. The read-out of blocking PI3K alone or in combination with other cancer pathways should mainly focus, besides the cytostatic effect, on cell death induction since sublethal damage may induce selection of more malignant clones. Targeting more than one pathway instead of a single agent approach may be more promising to kill GBM cell

    Territori lenti e resilienza locale. Il paradigma della lentezza come opportunitĂ  nel territorio sicano

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    Il contributo propone alcune riflessioni sulle opportunità di trasformazione dei territori interni e descrive i primi esiti di ricerca condotti nell’ambito del Laboratorio di Sviluppo Locale del “Polo Universitario di Ricerca di Bivona e Santo Stefano Quisquina per l’energia, l’ambiente e le risorse del territorio” , come motore dello sviluppo locale e dell’innovazione sociale dell’area interna dei Monti Sicani

    GPRD, A Database for the Spectral Properties of Diatomic Molecules of Atmospheric Interest

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    A short note describing the development of a database providing factual and numerical data on the spectral properties of diatomic molecules. This database is available online for the overall scientific community at the following adress: http://cfp.ist.utl.pt/radiation/Comment: 2 page

    The Density Effect in (W-S-W) Wood Connections with Internal Steel Plate and Passive Protection under Fire

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    The main objective of this work is to understand the fire behaviour of unprotected wood-to-wood connections with internal steel plate (W-S-W) in comparison with connections using passive protection with gypsum plasterboard. Passive fire protection uses systems that help prevent the spread of fire. Analytical methodologies according Eurocode 5 part 1-1 were used to the designed connections in different wood densities material. After that, to predict the fire exposure and the connection capacity a computational modelling was performed. Results of the temperature field and the char layer formation, for unprotected and protected members, were compared. Two different cross sections, only in wood or in wood-steel, were chosen to verify the evolution of charring rate effect.info:eu-repo/semantics/publishedVersio
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