Probing the Cosmic X-ray and MeV Gamma-ray Background Radiation through the Anisotropy

While the cosmic soft X-ray background is very likely to originate from individual Seyfert galaxies, the origin of the cosmic hard X-ray and MeV gamma-ray background is not fully understood. It is expected that Seyferts including Compton thick population may explain the cosmic hard X-ray background. At MeV energy range, Seyferts having non-thermal electrons in coronae above accretion disks or MeV blazars may explain the background radiation. We propose that future measurements of the angular power spectra of anisotropy of the cosmic X-ray and MeV gamma-ray backgrounds will be key to deciphering these backgrounds and the evolution of active galactic nuclei (AGNs). As AGNs trace the cosmic large-scale structure, spatial clustering of AGNs exists. We show that e-ROSITA will clearly detect the correlation signal of unresolved Seyferts at 0.5-2 keV and 2-10 keV bands and will be able to measure the bias parameter of AGNs at both bands. Once the future hard X-ray all sky satellites achieve the sensitivity better than 10^{-12} erg/cm^2/s at 10-30 keV or 30-50 keV - although this is beyond the sensitivities of current hard X-ray all sky monitors - angular power spectra will allow us to independently investigate the fraction of Compton-thick AGNs in all Seyferts. We also find that the expected angular power spectra of Seyferts and blazars in the MeV range are different by about an order of magnitude, where the Poisson term, so-called shot noise, is dominant. Current and future MeV instruments will clearly disentangle the origin of the MeV gamma-ray background through the angular power spectrum.Comment: 14 pages, 8 figures, accepted for publication in Ap

Probing the birth of fast rotating magnetars through high-energy neutrinos

We investigate the high-energy neutrino emission expected from newly born magnetars surrounded by their stellar ejecta. Protons might be accelerated up to 0.1-100 EeV energies possibly by, e.g., the wave dissipation in the winds, leading to hadronic interactions in the stellar ejecta. The resulting PeV-EeV neutrinos can be detected by IceCube/KM3Net with a typical peak time scale of a few days after the birth of magnetars, making the characteristic soft-hard-soft behavior. Detections would be important as a clue to the formation mechanism of magnetars, although there are ambiguities coming from uncertainties of several parameters such as velocity of the ejecta. Non-detections would also lead to useful constraints on the scenario.Comment: 5 pages, 3 figures, accepted for publication in PR

High-energy cosmic neutrinos as a probe of the vector mediator scenario in light of the muon g−2g-2 anomaly and Hubble tension

In light of the recent Muon $g-2$ experiment data from Fermilab, we investigate the implications of a gauged $L_{\mu} - L_{\tau}$ model for high energy neutrino telescopes. It has been suggested that a new gauge boson at the MeV scale can both account for the Muon $g-2$ data and alleviate the tension in the Hubble parameter measurements. It also strikes signals at IceCube from the predicted resonance scattering between high-energy neutrinos and the cosmic neutrino background. We revisit this model based on the latest IceCube shower data, and perform a four-parameter fit to find a preferred region. While the data are consistent with the absence of resonant signatures from secret interactions, we find the preferred region consistent with the muon $g-2$ anomaly and Hubble tension. We demonstrate that future neutrino telescopes such as IceCube-Gen2 can probe this unique parameter space, and point out that successful measurements would infer the neutrino mass with $0.05~{\rm eV}\lesssim \Sigma m_\nu\lesssim 0.3~{\rm eV}$.Comment: 5 pages, 4 figure

High energy neutrino early afterglows from gamma-ray bursts revisited

The high energy neutrino emission from gamma-ray bursts (GRBs) has been expected in various scenarios. In this paper, we study the neutrino emission from early afterglows of GRBs, especially under the reverse-forward shock model and late prompt emission model. In the former model, the early afterglow emission occurs due to dissipation made by an external shock with the circumburst medium (CBM). In the latter model, internal dissipation such as internal shocks produces the shallow decay emission in early afterglows. We also discuss implications of recent Swift observations for neutrino signals in detail. Future neutrino detectors such as IceCube may detect neutrino signals from early afterglows, especially under the late prompt emission model, while the detection would be difficult under the reverse-forward shock model. Contribution to the neutrino background from the early afterglow emission may be at most comparable to that from the prompt emission unless the outflow making the early afterglow emission loads more nonthermal protons, and it may be important in the very high energies. Neutrino-detections are inviting because they could provide us with not only information on baryon acceleration but also one of the clues to the model of early afterglows. Finally, we compare various predictions for the neutrino background from GRBs, which are testable by future neutrino-observations.Comment: 18 pages, 12 figures, accepted for publication in PR

ORP2 couples LDL-cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P-2 exchange

Low-density lipoprotein (LDL)-cholesterol delivery from late endosomes to the plasma membrane regulates focal adhesion dynamics and cell migration, but the mechanisms controlling it are poorly characterized. Here, we employed auxin-inducible rapid degradation of oxysterol-binding protein-related protein 2 (ORP2/OSBPL2) to show that endogenous ORP2 mediates the transfer of LDL-derived cholesterol from late endosomes to focal adhesion kinase (FAK)-/integrin-positive recycling endosomes in human cells. In vitro, cholesterol enhances membrane association of FAK to PI(4,5)P-2-containing lipid bilayers. In cells, ORP2 stimulates FAK activation and PI(4,5)P-2 generation in endomembranes, enhancing cell adhesion. Moreover, ORP2 increases PI(4,5)P-2 in NPC1-containing late endosomes in a FAK-dependent manner, controlling their tubulovesicular trafficking. Together, these results provide evidence that ORP2 controls FAK activation and LDL-cholesterol plasma membrane delivery by promoting bidirectional cholesterol/PI(4,5)P-2 exchange between late and recycling endosomes.Peer reviewe