70 research outputs found

    Landscapes of feeling arenas of action: information visualisation as art practice

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    Discussing his recent artworks alongside those by Abigail Reynolds, Lucy Kimbell and Christian Nold, the author examines emerging phenomena in the digital and wider fine arts whereby information visualization practices are approached as creative media. By laying bare points of convergence and divergence between artistic and scientific approaches, the article develops a number of arguments that show how the pictures produced by information visualization may be reframed within wider aesthetic and critical frameworks. Thus the author explores how models of image production derived from processes of scientific inquiry expand possibilities for the visual arts to develop new types of hybrid images that consist of data grounded both in material realities and in symbolic and aesthetic elements

    The Prediction of Gambling Behavior and Problem Gambling from Attitudes and Perceived Norms

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    The aim of this study was to characterise attitudes and social norms with respect to gambling among a population of adult Australians. A further aim was to evaluate whether gambling behaviour (as measured by its frequency) and problem gambling (as measured by its negative social effects on an individual) could be predicted by a model combining attitudes and social influences. With a sample of 215 late adolescents and adults, the Theory of Reasoned Action was found to significantly predict gambling frequency and problem gambling, with intentions predicting actual behaviour in both cases. Subjective norms only indirectly affected behaviour (through intention) in the case of problem gambling, but had both direct and indirect effects on gambling frequency, while attitudes to gambling predicted intentions, rather than directly predicting behaviour. Males were likely to gamble more often than females, and to judge their behaviour as a problem. Across the sample, although most had gambled at some time (89 per cent), gambling frequency and problem gambling were low, and attitudes and subjective norms with respect to gambling were a complex mixture of acceptance and rejection

    NMR investigation and secondary structure of domains I and II of rat brain calbindin D28k (1-93)

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    Calbindin D28k, a member of the troponin C superfamily of calcium- binding proteins, contains six putative EF hand domains but binds only four calcium-atoms: one at a binding site of very high affinity and three calcium-atoms at binding sites of lower affinity. The high- affinity site could be located within domain I while domains III, IV, and V bind calcium less tightly. The recombinant protein construct calb I-II (residues 1-93) comprising the first two EF hands affords a unique opportunity to study a pair of EF hands with one site binding calcium tightly and the second site empty. A series of heteronuclear 2D, 3D and 4D high-resolution NMR experiments were applied to calb I-II, and led to the complete assignment of the 1H, 13C and 15N resonances. The secondary structure of the protein was deduced from the size of the 3JHN-Halpha coupling constants, the chemical shift indices of 1Etaalpha, 13Calpha, 13C' and 13Cbeta nuclei and from an analysis of backbone NOEs observed in 3D and 4D NOESY spectra. Four major alpha- helices are identified: Ala13-Phe23, Gly33-Ala50, Leu54-Asp63, Val76- Leu90, while residues Ala2-Leu6 form a fifth, flexible helical segment. Two short beta-strands (Tyr30-Glu32, Lys72-Gly74) are found preceding helices B and D and are arranged in an anti-parallel interaction. Based on these data a structural model of calb I-II was constructed that shows that the construct adopts a tertiary structure related to other well-described calcium-binding proteins of the EF-hand family. Surprisingly, the protein forms a homodimer in solution, as was shown by its NMR characterization, size-exclusion chromatography and analytical ultra-centrifugation studies
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