Demographic change in the northern forest

This brief examines the population redistribution in the Northern Forest, which includes thirty-four counties scattered across northern and central Maine, New Hampshire, New York, and Vermont. Authors Ken Johnson, Susan Stewart, and Miranda Mockrin report that the population of the Northern Forest grew modestly between 2000 and 2010, and the population gains were greatest in recreational areas and least in manufacturing areas. Racial and ethnic diversity is also growing in the Northern Forest, and the population is getting older due to aging in place among current residents and net outmigration among younger populations

Second Generation of 'Miranda Procedure' for CP Violation in Dalitz Studies of B (\& D \& \tau) Decays

The `Miranda Procedure' proposed for analyzing Dalitz plots for CP asymmetries in charged B and D decays in a model-independent manner is extended and refined. The complexity of CKM CP phenomenology through order $\lambda^6$ is needed in searches for New Dynamics (ND). Detailed analyses of three-body final states other great advantages: (i) They give us more powerful tools for deciding whether an observed CP asymmetry rep- resents the manifestation of ND and its features. (ii) Many advantages can already be obtained by the `Miranda Procedure' without construction of a detailed Dalitz plot de- scription. (iii) One studies CP asymmetries independent of production asymmetries. We illustrate the power of a second generation Miranda Procedure with examples with time integrated rates for $B_d/\bar B_d$ decays to final states $K_S\pi+\pi-$ as trial runs with comments on $B^{\pm} \to K^{\pm}\pi^+\pi^-/K^{\pm}K^+K^-$.Comment: 29 pages, 7 figure

Modified quaternion Newton methods

We revisit the quaternion Newton method for computing roots of a class of quaternion valued functions and propose modified algorithms for finding multiple roots of simple polynomials. We illustrate the performance of these new methods by presenting several numerical experiments.The research was partially supported by the Research Centre of Mathematics of the University of Minho with the Portuguese Funds from the " Fundcao para a Ciencia e a Tecnologia", through the Project PEstOE/ MAT/ UI0013/ 2014

Fusão espectral de imagens de satélite no espaço de cores.

Espaço de cores RGB (red, green, blue). Espaço de cores IHS (intensity, hue, saturation). Espaço de cores LHS (lightness, hue, saturation). Métodos de interpolação. Estudo de caso.bitstream/CNPTIA/11920/1/comtec84.pdfAcesso em: 28 maio 2008

Analysis of the effects of an oncogenic stress on the cell cycle in human tumoral cells

Although differing only for the last 24 aminoacids, the three major isoforms of p21 Ras (Ha-, Ki- and N \u2013Ras) can trigger alternative pathways of signal transduction, at least in part as a consequence of different post-translational modifications and subcellular localization. Ras mutations are a common event in tumorigenesis. In colorectal carcinomas (CRCs) the mutations affect almost exclusively Ki-Ras, while Ha-Ras mutations are mostly found in bladder carcinomas and N-Ras mutations in leukemia cells. In almost all cases, the genetic alteration is a point mutation in codons 12 or 13, and less frequently in codon 61. By affecting the GTPase activity of the protein, they always lead to a constitutively active protein. However, data obtained in different experimental systems or by analysis of primary and metastatic tumors show that not only mutations of different isoforms of Ras, but also mutations in different codons or different mutations in the same codon of the same isoform of Ras may have diverse biological consequences. To shed more light on the molecular mechanisms responsible for the different effects of Ras mutations, we have obtained stable clones of HT-29 (a human colorectal adenocarcinoma cell line in which the endogenous Ras genes are wild type) transfected with cDNAs codifying Ha-RasG12V, Ki-RasG12V and Ki-RasG13D, under the control of an hormone-inducible promoter. We found that the expression of each of these mutated Ras isoforms induces specific, different effects on cell morphology and growth rate. FACS analysis shows also a differential effect on the cell cycle. H-RasG12V expression, in addition, induces apoptosis, through caspase activation mediated by p53 independent, MEK-1 dependent expression of the CDK inhibitor p21

Continuous spectra in high-harmonic generation driven by multicycle laser pulses

We present observations of the emission of XUV continua in the 20-37 eV region by high harmonic generation (HHG) with $4$-$7\ \mathrm{fs}$ pulses focused onto a Kr gas jet. The underlying mechanism relies on coherent control of the relative delays and phases between individually generated attosecond pulse, achievable by adjusting the chirp of the driving pulses and the interaction geometry. Under adequate negative chirp and phase matching conditions, the resulting interpulse interference yields a continuum XUV spectrum, which is due to both microscopic and macroscopic (propagation) contributions. This technique opens the route for modifying the phase of individual attosecond pulses and for the coherent synthesis of XUV continua from multicycle driving laser pulses without the need of an isolated attosecond burst.Comment: 14 pages, 5 figures. Submitted to Physical Review