Boydbolt, a positive-latch, simple-release fastener

Fastener /Boydbolt/ has recently been designed to furnish positive lock and release characteristics that positively prevent accidental adverse functions of lock or release

Mortality from head injury over four decades in Scotland

Although the causes of head injury, the population at risk and approaches to prevention and treatment are continually evolving, there is little information about how these are reflected in patterns of mortality over time. We used population based comprehensive data uniquely available in Scotland to investigate changes in the total numbers of deaths from 1974 to 2012, as well as the rates of head injury death, from different causes, overall and in relation to age and gender. Total mortality fell from an annual average of 503 to 339 with a corresponding annual decrease in rate from 9.6 to 6.4 per 100,000 population, the decline substantially occurring between 1974 and 1990. Deaths in children fell strikingly but rose in older people. Deaths in males fell to a greater extent than females but remained at a higher rate overall. Initially, a transport accident accounted for most deaths but these fell by 80%, from 325 per year to 65 per year over the 39 year period. Deaths from falling and all other causes did not decline, coming to outnumber transport accident deaths by 1998, which accounts for the overall absence of change in total mortality in recent years. In order to reduce mortality in the future, more effective measures to prevent falls are needed and these strategies will vary in younger adults (where alcohol is often a factor), and in older adults where infirmity can be a cause. In addition, measures to sustain reductions in transport accidents need to be maintained and further developed

KNEE POWER IN LOW BACK PAIN SUBJECTS DURING RUNNING

The purpose of this study was to examine lower extremity shock absorption between runners with and without low back pain. We compared data from three groups based on low back pain status: current low back pain, resolved pain after a single bout of low back pain and runners who never had low back pain (CTRL). All subjects ran at least 20 km per week and ran on a force treadmill at 3.8 m•s-1 while kinematic and kinetic data were collected. Work was determined from joint power histories during the shock attenuation portion of the stance phase. Individuals with a history of low back pain exhibited less peak knee negative power and negative work suggesting that they exhibited decreased eccentric muscle activity during foot-ground impact. The results of this study suggest that decreased eccentric activity of the muscles crossing the knee joint is associated with individuals who have low back pain and, to a lesser extent, with those who have residual low back pain. We suggest that the decreased eccentric activity can result in the footground impact shock wave moving through the lower extremity with little attenuation to the low back region

A Comparison Of Five Mechanical Work Algorithms For Different Footstrike Patterns And Speeds During Distance Running

The mechanical work done by a runner during an average stride cyde has been calculated with a variety of algorithms that generate values that may vary by an order of magnitude. The application of different algorithms to the same data set is uncommon, and does not seem to have been used at all to compare different foot strike patterns (FSP) during distance running. Average stride cycle values from five work algorithms for forefoot strike (ffs) and heel strike (hs) running at three different running speeds are presented. In general order from most to least restrictive: Wn allows no transfer between segments; Ww, within-segment transfer only; WwbAS, transfer within and between adjacent segments only; WwbLT, within and between segments of the same limb and the trunk; and, Wwb, within- and between-segment transfer with no restrictions. The primary difference in these algorithms is the amount of energy transfer they permit between and among body segments. Twelve highly skilled, male distance runners each ran with both FSP at three speeds ranging from 3.58 to 4.58 m-s-l. High-speed video (200 Hz) was used to track eight segment endpoint markers in the left sagittal plane. An ll-segment model was used with symmetry assumed to generate right side values. Among the algorithms, the no-transfer method (Wn) produced the highest work estimates. An absolute difference of -300 joules-stride-1 (-15-20%) existed across speeds between the no-transfer and within-transfer algorithms. There was then a relatively large decrease to the span of values generated from the other three algorithms. WwbAS was slightly higher than the remaining two algorithms, moreso in relative terms as speed increased. WwbLT increased slightly over speed (-40% slow->fast), while Wwb, the least restrictive, demonstrated almost no change across speeds (-1 % slow->fast). On average, these differences converged absolutely (75->20 joules-stride-1) and relatively (9.8%->2.5%) with increased speed; i.e., differences between the two .FSP decreased as speed increased. At all speeds for each algorithm, hs was lower than ffs. Collapsed across speeds, hs as percentage of ffs was 96.7 (Wn), 96.5 (ww)- 96.7 (WwbAS), 95.8 (WwbLT) and 89.4% (Wwb). Wwb across speeds consistently showed the largest relative differences between FSP, due perhaps in part to low absolute values. However, FSP differences still decreased with increased speed. This algorithm, therefore, appears to preserve the ordinal relationship and the trend in relative change between FSP across speeds reflected in the other four algorithms. Overall, the consistency across all algorithms of absolute and relative decrease between FSP with increased speed suggests variations in actual kinematics, not algorithms, are responsible for observed differences

Transcriptome analysis of porcine M. semimembranosus divergent in intramuscular fat as a consequence of dietary protein restriction

peer-reviewedBackground: Intramuscular fat (IMF) content is positively correlated with aspects of pork palatability, including flavour, juiciness and overall acceptability. The ratio of energy to protein in the finishing diet of growing pigs can impact on IMF content with consequences for pork quality. The objective of this study was to compare gene expression profiles of Musculus semimembranosus (SM) of animals divergent for IMF as a consequence of protein dietary restriction in an isocaloric diet. The animal model was derived through the imposition of low or high protein diets during the finisher stage in Duroc gilts. RNA was extracted from post mortem SM tissue, processed and hybridised to Affymetrix porcine GeneChip® arrays. Results: IMF content of SM muscle was increased on the low protein diet (3.60 ± 0.38% versus 1.92 ± 0.35%). Backfat depth was also greater in animals on the low protein diet, and average daily gain and feed conversion ratio were lower, but muscle depth, protein content and moisture content were not affected. A total of 542 annotated genes were differentially expressed (DE) between animals on low and high protein diets, with 351 down-regulated and 191 up-regulated on the low protein diet. Transcript differences were validated for a subset of DE genes by qPCR. Alterations in functions related to cell cycle, muscle growth, extracellular matrix organisation, collagen development, lipogenesis and lipolysis, were observed. Expression of adipokines including LEP, TNFα and HIF1α were increased and the hypoxic stress response was induced. Many of the identified transcriptomic responses have also been observed in genetic and fetal programming models of differential IMF accumulation, indicating they may be robust biological indicators of IMF content. Conclusion: An extensive perturbation of overall energy metabolism in muscle occurs in response to protein restriction. A low protein diet can modulate IMF content of the SM by altering gene pathways involved in lipid biosynthesis and degradation; however this nutritional challenge negatively impacts protein synthesis pathways, with potential consequences for growth.Department of Agriculture, Food and the Marine, Ireland - Food Institutional Research Measur

As We See It; Classroom Teachers View Reading Recovery

This is the second article in this special issue not written by Reading Recovery trained teachers. Hamill and Kelly are first grade teachers in one of the 26 participating schools in the first year of Reading Recovery implementation in Michigan. In response to questions by the editor of Reading Horizons, they explain the program — its impact on the Reading Recovery children and on their classroom teaching. Clearly the concerted work of the Reading Recovery teacher-in-training and these teachers demonstrates that the Reading Recovery program is an intervention in the education system, as well as a program for children