A New All-Sky Catalog of Stars with Large Proper Motions

A new all-sky catalog of stars with proper motions pm>0.15"/yr is presented. The catalog is largely a product of the SUPERBLINK survey, a data-mining initiative in which the entire Digitized Sky Surveys are searched for moving stellar sources. Findings from earlier proper motions surveys are also incorporated. The new all-sky catalog supersedes the great historic proper motion catalogs assembled by W. J. Luyten (LHS, NLTT), and provides a virtually complete (>98%) census of high proper motion stars down to magnitude R=19.Comment: To appear in proceedings of IAU Symposium No. 248 - A Giant Step: from Milli- to Micro-arcsecond Astrometry, Shangai : China (2007

American Indians and the Nevada Test Site: A Model of Research and Consultation

This book examines the long -term consultation partnership involving a federal agency, a group of American Indian tribes, and a team of anthropologists. This book highlights the history, evolution, dynamics, and results of the consultation relationship between the U.S. Department of Energy Nevada Operations Office (DOE/NV) and 20 tribes and organizations composed of ethnic Numic-speaking Western Shoshone, Southern Paiute, and Owens Valley Paiute -Shoshone people. A team of applied anthropologists currently affiliated with the Bureau of Applied Research in Anthropology at the University of Arizona in Tucson (UofA), and a team of archaeologists from the Desert Research Institute (DRI), a unit of the University and Community College System of Nevada in Reno and Las Vegas, Nevada, respectively, have provided technical assistance and contract consulting services to the Indian tribes and the DOE/NV, first on the Yucca Mountain Site Characterization Office (YMSCO) and, in the past decade, on the Nevada Test Site (NTS). During the early stages of the consultation relationship, the culturally affiliated Indian and pan-Indian entities unified themselves into a single indigenous organization, the Consolidated Group of Tribes and Organizations, or CGTO, for the purpose of defending their collective interests in the lands and resources comprising the NTS in south –central Nevada. Since 1994, this new Indian organization has consulted with the DOE/NV on an increasingly wider range of issues that affect Indian cultural, religious, and resource values on and around the NTS. The book also examines these cultural and religious values regarding traditional lands and resources, and the cultural significance of resources, objects, places, and landscapes within the boundaries of this facility that have been affected by DOE/NV mission activities. The consultation relationship was initiated, and continues into the present, as a result of the implementation of a series of federal environmental laws and regulations that require consultation with American Indian tribal governments when activities conducted with federal funds, in federal facilities, or both, have the potential to adversely impact traditional American Indian resources and cultural practices. Most notable among these is the American Indian Religious Freedom Act (AIRFA), which was passed by the United States Congress in 1978. Prior to that time, cultural resources were managed mainly in accordance with the provisions set forth in Sections 106 and 110 of the National Historic Preservation Act.This item is part of the Richard Stoffle Collection. It was digitized from a physical copy provided by Richard Stoffle, Bureau of Applied Research in Anthropology, School of Anthropology at the University of Arizona. For more information about items in this collection, please email Special Collections, [email protected]

Native American Graves Protection and Repatriation Act Consultation and the Nevada Test Site Collection

This report summarizes a compliance consultation between the Department of Energy/ Nevada Operations Office (DOE/NV) and the American Indian tribes and Indian organizations that make up the Consolidated Group of Tribes and Organizations (CGTO). The consultation focused on artifacts removed from the Nevada Test Site (NTS). The report describes consultation actions and recommendations that occurred in compliance with the Native American Graves Protection and Repatriation Act (NAGPRA).This item is part of the Richard Stoffle Collection. It was digitized from a physical copy provided by Richard Stoffle, Bureau of Applied Research in Anthropology, School of Anthropology at the University of Arizona. For more information about items in this collection, please email Special Collections, [email protected]

High levels of sewage contamination released from urban areas after storm events: A quantitative survey with sewage specific bacterial indicators.

BACKGROUND:Past studies have demonstrated an association between waterborne disease and heavy precipitation, and climate change is predicted to increase the frequency of these types of intense storm events in some parts of the United States. In this study, we examined the linkage between rainfall and sewage contamination of urban waterways and quantified the amount of sewage released from a major urban area under different hydrologic conditions to identify conditions that increase human risk of exposure to sewage. METHODS AND FINDINGS:Rain events and low-flow periods were intensively sampled to quantify loads of sewage based on two genetic markers for human-associated indicator bacteria (human Bacteroides and Lachnospiraceae). Samples were collected at a Lake Michigan estuary and at three river locations immediately upstream. Concentrations of indicators were analyzed using quantitative polymerase chain reaction (qPCR), and loads were calculated from streamflow data collected at each location. Human-associated indicators were found during periods of low flow, and loads increased one to two orders of magnitude during rain events from stormwater discharges contaminated with sewage. Combined sewer overflow (CSO) events increased concentrations and loads of human-associated indicators an order of magnitude greater than heavy rainfall events without CSO influence. Human-associated indicator yields (load per km2 of land per day) were related to the degree of urbanization in each watershed. Contamination in surface waters were at levels above the acceptable risk for recreational use. Further, evidence of sewage exfiltration from pipes threatens drinking water distribution systems and source water. While this study clearly demonstrates widespread sewage contamination released from urban areas, a limitation of this study is understanding human exposure and illness rates, which are dependent on multiple factors, and gaps in our knowledge of the ultimate health outcomes. CONCLUSIONS:With the prediction of more intense rain events in certain regions due to climate change, sewer overflows and contamination from failing sewer infrastructure may increase, resulting in increases in waterborne pathogen burdens in waterways. These findings quantify hazards in exposure pathways from rain events and illustrate the additional stress that climate change may have on urban water systems. This information could be used to prioritize efforts to invest in failing sewer infrastructure and create appropriate goals to address the health concerns posed by sewage contamination from urban areas

High levels of sewage contamination released from urban areas after storm events: A quantitative survey with sewage specific bacterial indicators - Fig 2

<p>(A) Streamflow (upper panel) and corresponding HB, Lachno2, ruminant, <i>E</i>. <i>coli</i>, and enterococci indicator concentrations (lower panel) measured during a combined sewer overflow in the Milwaukee estuary in Milwaukee, Wisconsin from 4/9/2015–4/13/2015 and (B) streamflow (upper panel) and corresponding HB, Lachno2, ruminant, <i>E</i>. <i>coli</i>, and enterococci indicator concentrations (lower panel) measured during two rain events in the Milwaukee estuary in Milwaukee, Wisconsin from 6/11/2015–6/13/2015 (event 8) and 6/14 /2015–6/16/15 (event 9). Vertical black dashed lines represent the beginning and ending dates and times that were defined for each event. HB, human <i>Bacteroides</i>; Lachno2, human Lachnospiraceae.</p

Protein O-Linked Mannose β-1,4-N-Acetylglucosaminyl-transferase 2 (POMGNT2) Is a Gatekeeper Enzyme for Functional Glycosylation of α-Dystroglycan

Disruption of the O-mannosylation pathway involved in functional glycosylation of α-dystroglycan gives rise to congenital muscular dystrophies. Protein O-linked mannose β-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) catalyzes the first step toward the functional matriglycan structure on α-dystroglycan that is responsible for binding extracellular matrix proteins and certain arenaviruses. Alternatively, protein O-linked mannose β-1,2-N-acetylglucosaminyltransferase 1 (POMGNT1) catalyzes the first step toward other various glycan structures present on α-dystroglycan of unknown function. Here, we demonstrate that POMGNT1 is promiscuous for O-mannosylated peptides, whereas POMGNT2 displays significant primary amino acid selectivity near the site of O-mannosylation. We define a POMGNT2 acceptor motif, conserved among 59 vertebrate species, in α-dystroglycan that when engineered into a POMGNT1-only site is sufficient to convert the O-mannosylated peptide to a substrate for POMGNT2. Additionally, an acceptor glycopeptide is a less efficient substrate for POMGNT2 when two of the conserved amino acids are replaced. These findings begin to define the selectivity of POMGNT2 and suggest that this enzyme functions as a gatekeeper enzyme to prevent the vast majority of O-mannosylated sites on proteins from becoming modified with glycan structures functional for binding laminin globular domain-containing proteins

Biological Denitrification in Drinking Water Treatment Using the Seaweed Gracilaria Verrucosa as Carbon Source and Biofilm Carrier

WOS: 000237667600011PubMed ID: 16749311Chemical and microbiological aspects were investigated with regard to biological denitrification of drinking water using the seaweed Gracilaria verrucosa as the carbon and energy substrate and as physical support for the microbial flora in semibatch, fixed-bed reactors. Complete removal of nitrate (100 mg/L) was readily achieved without accumulation of nitrite. Microbiological analysis indicated that the effluent of the reactor contained high numbers of bacteria (> 10(6)/mL total count). Among the 44 bacterial strains isolated directly from the samples or isolated after enrichment at 37 degrees C, 25 different fatty acid profiles were found, indicating a complex microflora, including potential pathogens