The effect of excess dietary manganese on uninfected and Ascaridia galli infected chicks

Abstract The effect of dietary manganese from two different sources on chicks (uninfected and infected with Ascaridia galli) was studied

Effect of selenium and Ascaridia galli infection on antioxidant biomarkers in broiler chickens: a mathematical model for parasite reduction and host growth

The activity of selenium-dependent glutathione peroxidase (GPX), liver concentration of vitamin E, and plasma and liver selenium levels were used for estimation of the antioxidant status of broiler chickens infected with Ascaridia galli. These biomarkers were recorded in an experiment covering 70 days p.i. At the same time the establishment rate of A. galli in chicken intestines, gain in the host body weight and chicken survival were studied. Broiler chickens (Cobb hybrids) were infected with 1450 embryonated A. galli eggs and treated with Sel-plex. A mathematical model was applied to determine the rate of nematode reduction and the relative rate of gain of host body weight, which are essential kinetic parameters of parasite-host interaction. The activity of GPX increased with both elevated selenium and reduced infection levels. The concentrations of selenium and vitamin E, and the GPX activity in the infected chickens demonstrated a similar pattern of change with time after day 30 p.i. The supplementation of the broilers with dietary selenium in the form of Sel-plex improved their antioxidant status. Increases by 29% in vitamin E concentration, 15% in GPX activity, and 22% in liver selenium concentration, respectively, were recorded in the infected and treated, compared to infected and untreated broilers

Administration of Zn-Co-Mn basic salt to chickens with ascaridiosis - II. Sex ratio and microelement levels in Ascaridia galli and in treated and untreated chickens

Hisex chickens were infected with 1,450 embryonated Ascaridia galli eggs and treated with a new synthesized basic mixed salt (ZnxCoyMn1-x-y)(.)(OH)(6)SO(4.)2H(2)O). The worm burden was determined and sex ratios for A. galli of M:F=1.4 and M:F=2 in untreated and treated chickens, respectively, were found. A decrease in the mean establishment rate of A. galli in treated chickens was observed. The levels of zinc, cobalt and manganese were determined in liver and muscle of the host and in male and female A. galli. The survival of the chickens and gain in body weight were improved, and the restoration of microelement content was observed by treatment with the salt. A positive effect of the basic Zn-Co-Mn salt was also observed in the nematode microelement levels. Significant differences were found between the levels of zinc, cobalt and manganese in male and female A. galli

Effect of mixed basic salts on live performance and trace metals in growing rabbits infected with Fasciola hepatica

6 pages, 4 tables.The aim of our study was to assess the effects of mixed basic salts on growth and liver trace metals content of rabbits infected with Fasciola hepatica. Chinchilla rabbits were experimentally infected with Fasciola hepatica and treated with triple hydroxy crystals newly synthesized (ZnxCoyCu1-x-y)4(OH) 6SO4.2H2O and (ZnxCoyMn1-x-y)4(OH) 6SO4.2H2O. Body weight gain, feed intake, feed conversion, mortality and trace metal (Zn, Mn, Co, Cu, Al) were studied on day 14th and 60th p.i. Trace metals were established by AAS. Trace metals imbalance was observed in acute and chronic fasciolosis — reduced levels of metals. Supplementation of ZnCo,Mn - salt influenced positively Mn, Zn and Co content and Zn, Co, Cu - salt increased Co, Cu and Zn levels. BWG and mortality were changed positively by the both salts. Feed intake and feed conversion were not influenced by treatment with both salts. Treatment with Zn-Co-Mn salt has more beneficial effects on BWG in the rabbits (infected or uninfected) and liver trace metal imbalance associated with acute and chronic fasciolosis than Zn-Co-Cu salt.The study was supported by Spanish-Bulgarian Scientific Cooperation (CSIC-BAS)-2005BG008.Peer reviewe