45,257 research outputs found

    Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers

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    A polymer microfluidic device has been fabricated using rapid prototyping techniques. The device was built up to allow the formation and subsequent investigation of artificial bilayer lipid membranes (BLMs). A simple dry film photoresist stamp was used to hot emboss microfluidic channels into PMMA films. Laser micromachining was employed to form an aperture into PMMA films. Laser micromachining was employed to form an aperture through the PMMA channels, across which the BLM was later formed. The dry film phororesist was also used as a simple etch mask for the deep etching of glass substrates in buffered HF solutions, which was used in this work for the production of glass embossing stamps. We show that bilayer films can be successfully produced across laser micromachined apertures in PMMA films

    WILLIAM REYNOLDS VANCE

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    Radioisotope thermal photovoltaic application of the GaSb solar cell

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    An examination of a RTVP (radioisotopic thermophotovoltaic) conceptual design has shown a high potential for power densities well above those achievable with radioisotopic thermoelectric generator (RTG) systems. An efficiency of 14.4 percent and system specific power of 9.25 watts/kg were predicted for a system with sixteen GPHS (general purpose heat source) sources operating at 1100 C. The models also showed a 500 watt system power by the strontium-90 isotope at 1200 C at an efficiency of 17.0 percent and a system specific power of 11.8 watts/kg. The key to this level of performance is a high-quality photovoltaic cell with narrow bandgap and a reflective rear contact. Recent work at Boeing on GaSb cells and transparent back GaAs cells indicate that such a cell is well within reach

    Calibration of Viking imaging system pointing, image extraction, and optical navigation measure

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    Pointing control and knowledge accuracy of Viking Orbiter science instruments is controlled by the scan platform. Calibration of the scan platform and the imaging system was accomplished through mathematical models. The calibration procedure and results obtained for the two Viking spacecraft are described. Included are both ground and in-flight scan platform calibrations, and the additional calibrations unique to optical navigation

    Gypsy moths and American dog ticks: Space partners

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    An experiment intended for the space shuttle and designed to investigate the effects of weightlessness and total darkness on gypsy moth eggs and engorged American dog ticks is described. The objectives are: (1) to reevaluate the effects of zero gravity on the termination of diapause/hibernation of embryonated gypsy moth eggs, (2) to determine the effect of zero gravity on the ovipositions and subsequent hatch from engorged female American dog ticks that have been induced to diapause in the laboratory, and (3) to determine whether morphological or biochemical changes occur in the insects under examination. Results will be compared with those from a similar experiment conducted on Skylab 4

    Microlensing of the Lensed Quasar SDSS0924+0219

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    We analyze V, I and H band HST images and two seasons of R-band monitoring data for the gravitationally lensed quasar SDSS0924+0219. We clearly see that image D is a point-source image of the quasar at the center of its host galaxy. We can easily track the host galaxy of the quasar close to image D because microlensing has provided a natural coronograph that suppresses the flux of the quasar image by roughly an order of magnitude. We observe low amplitude, uncorrelated variability between the four quasar images due to microlensing, but no correlated variations that could be used to measure a time delay. Monte Carlo models of the microlensing variability provide estimates of the mean stellar mass in the lens galaxy (0.02 Msun < M < 1.0 Msun), the accretion disk size (the disk temperature is 5 x 10^4 K at 3.0 x 10^14 cm < rs < 1.4 x 10^15 cm), and the black hole mass (2.0 x 10^7 Msun < MBH \eta_{0.1}^{-1/2} (L/LE)^{1/2} < 3.3 x 10^8 Msun), all at 68% confidence. The black hole mass estimate based on microlensing is consistent with an estimate of MBH = 7.3 +- 2.4 x 10^7 Msun from the MgII emission line width. If we extrapolate the best-fitting light curve models into the future, we expect the the flux of images A and B to remain relatively stable and images C and D to brighten. In particular, we estimate that image D has a roughly 12% probability of brightening by a factor of two during the next year and a 45% probability of brightening by an order of magnitude over the next decade.Comment: v.2 incorporates referee's comments and corrects two errors in the original manuscript. 28 pages, 10 figures, published in Ap

    Legal uncertainty under EU acquis for the author of Graphical User Interface design - A new sui generis protection needed?

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    This thesis is about the legal protection of the Intellectual Property (IP) of the design of the graphical user interface (GUI) for computer programs aka software. The research into this matter of law was done by finding out and analysing how this protection is provided through international treaties, statutory law and case law. It concludes that there is a certain amount of legal uncertainty within the area researched and that full harmonization of IPRs within EU most probably would remove this issue and thereby benefit the individual author. This thesis takes the reader on a journey where we will explore the dimension where law and technology meet and merge

    Anchoring In Action: Manual Estimates Of Slant Are Powerfully Biased Toward Initial Hand Orientation And Are Correlated With Verbal Report

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    People verbally overestimate hill slant by approximately 15 degrees to 25 degrees, whereas manual estimates (e. g., palm board measures) are thought to be more accurate. The relative accuracy of palm boards has contributed to the widely cited theoretical claim that they tap into an accurate, but unconscious, motor representation of locomotor space. In the current work, 4 replications (total N = 204) carried out by 2 different laboratories tested an alternative anchoring hypothesis that manual action measures give low estimates because they are always initiated from horizontal. The results of all 4 replications indicate that the bias from response anchoring can entirely account for the difference between manual and verbal estimates. Moreover, consistent correlations between manual and verbal estimates given by the same observers support the conclusion that both measures are based on the same visual representation. Concepts from the study of judgment under uncertainty apply even to action measures in information rich environments
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