Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Arbitrating Risk through Moral Values: The Case of Kenyan Fair Trade’, in Hidden Hands in the Market: Ethnographies of Fair Trade, Ethical Consumption, and Corporate Social Responsibility

This chapter examines the Kenyan Fairtrade flower as a site of value making, one that provides a constructive lens into how moral obligation and ethical accountability are shaped by risk perceptions and become visible through the process of transnational commodity exchange. Specifically, it argues that while Fairtrade labeling responds to the risks of corporate capitalism through consumption practices predicated on extending care and compassion to distant communities, it is also embedded within commodity chains that advance liberal ethics as a mode of “governmentality” over African producers. These ethics are associated with new technologies of information gathering, regulation, and surveillance that simultaneously assuage consumers’ anxieties and channel their sympathy-based humanism into new forms of ethical normativity. Fairtrade's relational ethic, for example, is accompanied by a private regulatory assemblage that authorizes certain knowledge forms, thereby circumscribing the social and economic rights available as well as the form of personhood through which they can be claimed. Thus, although Fairtrade is cast as morally unproblematic, it can also serve as a mechanism through which specific interests are naturalized and circulated through a benevolent vernacular of economic and social rights