335 research outputs found

    Density fluctuations and phase separation in a traffic flow model

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    Within the Nagel-Schreckenberg traffic flow model we consider the transition from the free flow regime to the jammed regime. We introduce a method of analyzing the data which is based on the local density distribution. This analyzes allows us to determine the phase diagram and to examine the separation of the system into a coexisting free flow phase and a jammed phase above the transition. The investigation of the steady state structure factor yields that the decomposition in this phase coexistence regime is driven by density fluctuations, provided they exceed a critical wavelength.Comment: in 'Traffic and Granular Flow 97', edited by D.E. Wolf and M. Schreckenberg, Springer, Singapore (1998

    Critical and Near-Critical Branching Processes

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    Scale-free dynamics in physical and biological systems can arise from a variety of causes. Here, we explore a branching process which leads to such dynamics. We find conditions for the appearance of power laws and study quantitatively what happens to these power laws when such conditions are violated. From a branching process model, we predict the behavior of two systems which seem to exhibit near scale-free behavior--rank-frequency distributions of number of subtaxa in biology, and abundance distributions of genotypes in an artificial life system. In the light of these, we discuss distributions of avalanche sizes in the Bak-Tang-Wiesenfeld sandpile model.Comment: 9 pages LaTex with 10 PS figures. v.1 of this paper contains results from non-critical sandpile simulations that were excised from the published versio

    The Impact II, a Very High-Resolution Quadrupole Time-of-Flight Instrument (QTOF) for Deep Shotgun Proteomics

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    Hybrid quadrupole time-of-flight (QTOF) mass spectrometry is one of the two major principles used in proteomics. Although based on simple fundamentals, it has over the last decades greatly evolved in terms of achievable resolution, mass accuracy, and dynamic range. The Bruker impact platform of QTOF instruments takes advantage of these developments and here we develop and evaluate the impact II for shotgun proteomics applications. Adaption of our heated liquid chromatography system achieved very narrow peptide elution peaks. The impact II is equipped with a new collision cell with both axial and radial ion ejection, more than doubling ion extraction at high tandem MS frequencies. The new reflectron and detector improve resolving power compared with the previous model up to 80%, i.e. to 40,000 at m/z 1222. We analyzed the ion current from the inlet capillary and found very high transmission (>80%) up to the collision cell. Simulation and measurement indicated 60% transfer into the flight tube. We adapted MaxQuant for QTOF data, improving absolute average mass deviations to better than 1.45 ppm. More than 4800 proteins can be identified in a single run of HeLa digest in a 90 min gradient. The workflow achieved high technical reproducibility (R2 > 0.99) and accurate fold change determination in spike-in experiments in complex mixtures. Using label-free quantification we rapidly quantified haploid against diploid yeast and characterized overall proteome differences in mouse cell lines originating from different tissues. Finally, after high pH reversed-phase fractionation we identified 9515 proteins in a triplicate measurement of HeLa peptide mixture and 11,257 proteins in single measurements of cerebellum-the highest proteome coverage reported with a QTOF instrument so far

    Dense transcript profiling in single cells by image correlation decoding

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    Sequential barcoded fluorescent in situ hybridization (seqFISH) allows large numbers of molecular species to be accurately detected in single cells, but multiplexing is limited by the density of barcoded objects. We present correlation FISH (corrFISH), a method to resolve dense temporal barcodes in sequential hybridization experiments. Using corrFISH, we quantified highly expressed ribosomal protein genes in single cultured cells and mouse thymus sections, revealing cell-type-specific gene expression

    Universal 1/f Noise from Dissipative SOC Models

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    We introduce a model able to reproduce the main features of 1/f noise: hyper-universality (the power-law exponents are independent on the dimension of the system; we show here results in d=1,2) and apparent lack of a low-frequency cutoff in the power spectrum. Essential ingredients of this model are an activation-deactivation process and dissipation.Comment: 3 Latex pages, 2 eps Figure

    Meson-Baryon Form Factors in Chiral Colour Dielectric Model

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    The renormalised form factors for pseudoscalar meson-baryon coupling are computed in chiral colour dielectric model. This has been done by rearranging the Lippmann-Schwinger series for the meson baryon scattering matrix so that it can be expressed as a baryon pole term with renormalized form factors and baryon masses and the rest of the terms which arise from the crossed diagrams. Thus we are able to obtain an integral equation for the renormalized meson-baryon form factors in terms of the bare form factors as well as an expression for the meson self energy. This integral equation is solved and renormalized meson baryon form factors and renormalized baryon masses are computed. The parameters of the model are adjusted to obtain a best fit to the physical baryon masses. The calculations show that the renormalized form factors are energy-dependent and differ from the bare form factors primarily at momentum transfers smaller than 1 GeV. At nucleon mass, the change in the form factors is about 10% at zero momentum transfer. The computed form factors are soft with the equivalent monopole cut-off mass of about 500 MeV. The renormalized coupling constants are obtained by comparing the chiral colour dielectric model interaction Hamiltonian with the standard form of meson-nucleon interaction Hamiltonian. The ratio of ΔNπ\Delta N\pi and NNπNN\pi coupling constants is found to be about 2.15. This value is very close to the experimental value.Comment: 16 pages, 7 postscript figure

    Dihyperon in Chiral Colour Dielectric Model

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    The mass of dihyperon with spin, parity Jπ=0+J^{\pi}=0^{+} and isospin I=0I = 0 is calculated in the framework of Chiral colour dielectric model. The wave function of the dihyperon is expressed as a product of two colour-singlet baryon clusters. Thus the quark wave functions within the cluster are antisymmetric. Appropriate operators are then used to antisymmetrize inter-cluster quark wave functions. The radial part of the quark wavefunctions are obtained by solving the the quark and dielectric field equations of motion obtained in the Colour dielectric model. The mass of the dihyperon is computed by including the colour magnetic energy as well as the energy due to meson interaction. The recoil correction to the dihyperon mass is incorporated by Peierls-Yoccoz technique. We find that the mass of the dihyperon is smaller than the Λ−Λ\Lambda-\Lambda threshold by over 100 MeV. The implications of our results on the present day relativistic heavy ion experiments is discussed.Comment: LaTeX, 13 page
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