The Role of Email Communications in Determining Response Rates and Mode of Participation in a Mixed-mode Design

This article is concerned with the extent to which the propensity to participate in a web-face-to-face sequential mixed-mode survey is influenced by the ability to communicate with sample members by email in addition to mail. Researchers may be able to collect email addresses for sample members and to use them subsequently to send survey invitations and reminders. However, there is little evidence regarding the value of doing so. This makes it difficult to decide what efforts should be made to collect such information and how to subsequently use it efficiently. Using evidence from a randomized experiment within a large mixed-mode national survey, we find that using a respondent-supplied email address to send additional survey invites and reminders does not affect survey response rate but is associated with an increased proportion of responses by web rather than face to face and, hence, lower survey costs

TTIP: Political and economic rationale and implications

The Transatlantic Trade and Investment Partnership will reduce tariffs and lower regulatory hurdles that currently impair trade between the EU and the US. However, TTIP has been controversial from the outset. Non-governmental organisations are concerned about lowered health and environmental standards, unions fear a further weakening of labour conditions, and economists debate whether or not there will actually be any noticeable impact on employment and GDP growth. This Forum, featuring contributions by the speakers at the 2015 Intereconomics conference, presents a balanced overview of both the prospective benefits as well as the possible drawbacks to the potentially monumental trade agreement

Understanding Society Innovation Panel Wave 8: results from methodological experiments

This paper presents some preliminary findings from Wave 8 of the Innovation Panel (IP8) of Understanding Society: The UK Household Longitudinal Study. Understanding Society is a major panel survey in the UK. May 2015, the eighth wave of the Innovation Panel went into the field. IP8 used a mixed-mode design, using on-line interviews and face-to-face interviews. This paper describes the design of IP8, the experiments carried and the preliminary findings from early analysis of the data

Understanding Society Innovation Panel Wave 9: Results from Methodological Experiments. Understanding Society Working Paper Series

This paper presents some preliminary findings from Wave 9 of the Innovation Panel (IP9) of Understanding Society: The UK Household Longitudinal Study. Understanding Society is a major panel survey in the UK. IP9 included experiments on the use mixed mode data collection, the value of respondent incentives, targeted timing of email invitations, measurement of household finances, subjective expectations about returns to schooling, people’s assessment of what constitutes “successful ageing”, format of response options, use of multiple measurements to improve measurement of attitudes, and measurement of sensitive topics. This paper describes the design of IP9, the experiments carried and the preliminary findings from early analysis of the data

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

The Impact of Mixing Modes on Reliability in Longitudinal Studies

Mixed-mode designs are increasingly important in surveys, and large longitudinal studies are progressively moving to or considering such a design. In this context, our knowledge regarding the impact of mixing modes on data quality indicators in longitudinal studies is sparse. This study tries to ameliorate this situation by taking advantage of a quasi-experimental design in a longitudinal survey. Using models that estimate reliability for repeated measures, quasi-simplex models, 33 variables are analyzed by comparing a single-mode CAPI design to a sequential CATI-CAPI design. Results show no differences in reliabilities and stabilities across mixed modes either in the wave when the switch was made or in the subsequent waves. Implications and limitations are discussed. </jats:p

Synchronous PWM control of triple transformer-connected inverters for photovoltaic system

Abstract: This paper presents results of research of modulation processes in power conversion system with triple voltage source inverters, supplied by photovoltaic (PV) strings, and connected to a four-winding transformer. The transformer has in this case specific connections between the secondary windings and inverters, allowing providing of multilevel voltages at secondary windings of the transformer. Specialized space-vector-based strategy of pulsewidth modulation (PWM) has been used for control of inverters, insuring quarter-wave symmetry of winding voltages for any modulation indices and switching frequency of inverters. Analysis and comparison of harmonic composition of winding voltages and output voltages of inverters has been done. The validity of the analyzed processes has been verified by simulations: three basic variants of the scheme of modulation have been applied for control of inverters

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

Multiphase quad-inverter system with feedforward synchronous PWM and nonlinear voltage regulation

Abstract: This manuscript presents modified scheme of synchronous space-vector modulation allowing providing nonlinear dependences between the fundamental voltage and fundamental frequency of dual three-phase open-winding ac drive with four modulated inverters. Behavior of the system with six control modes (characterized by different dc-voltages and switching frequencies of inverters) and two nonlinear Voltage/Frequency ratios has been analyzed and simulated by the means of MATLAB-software