Stress testing as an instrument for bank liquidity risk assessment

У статті проводиться узагальнення теоретичних аспектів оцінки ризику ліквідності на основі застосування методики стрес-тестування. Уточнено класифікацію стрес-тестів та механізм проведення стрес-тестування на рівні окремих портфелів банку.The article is devoted to the generalization of the theoretical aspects of the liquidity risk estimation on the basis of application of stress testing method. The classification of stress tests and the mechanism of carrying out of stress testing at the level of separate portfolios of bank are specified

Ferrocenylselenoamides: Synthesis, Characterization and Cytotoxic Properties

A new series of ferrocenyl selenoamides <b>7</b>–<b>11</b> (FcSeNH­(CH₂)<i>_n</i>CH₂(R)­OH, <i>n</i> = 1, 2, 3, R = H, Me, Ph) were prepared in good yields by selenative demetalation of Fischer aminocarbene complexes. The crystal structures of <b>7</b> [FcSeNH­(CH₂)₂OH] and <b>19</b> [PhSeNH­(CH₂)₂OH] reveal their capability to form intermolecular hydrogen bonding in solid state. Results of SRB assays show that these new selenium compounds have a good anticancer potency superior to tamoxifen and cisplatin, with IC₅₀ values ranging from 4.5 to 13.32 μM against human breast cancer cell lines. A preliminary model to explain the structure–cytotoxic activity relation is proposed where different structural parameters such as the alkyl chain length, the presence of bulky groups in the same chain, the effect of hydroxyl group, and also the role of ferrocene moiety are included as being responsible for the cytotoxic response

Ferrocenylselenoamides: Synthesis, Characterization and Cytotoxic Properties

A new series of ferrocenyl selenoamides <b>7</b>–<b>11</b> (FcSeNH­(CH₂)<i>_n</i>CH₂(R)­OH, <i>n</i> = 1, 2, 3, R = H, Me, Ph) were prepared in good yields by selenative demetalation of Fischer aminocarbene complexes. The crystal structures of <b>7</b> [FcSeNH­(CH₂)₂OH] and <b>19</b> [PhSeNH­(CH₂)₂OH] reveal their capability to form intermolecular hydrogen bonding in solid state. Results of SRB assays show that these new selenium compounds have a good anticancer potency superior to tamoxifen and cisplatin, with IC₅₀ values ranging from 4.5 to 13.32 μM against human breast cancer cell lines. A preliminary model to explain the structure–cytotoxic activity relation is proposed where different structural parameters such as the alkyl chain length, the presence of bulky groups in the same chain, the effect of hydroxyl group, and also the role of ferrocene moiety are included as being responsible for the cytotoxic response