2,712 research outputs found
Electron Energy Distributions at Relativistic Shock Sites: Observational Constraints from the Cygnus A Hotspots
We report new detections of the hotspots in Cygnus A at 4.5 and 8.0 microns
with the Spitzer Space Telescope. Together with detailed published radio
observations and synchrotron self-Compton modeling of previous X-ray
detections, we reconstruct the underlying electron energy spectra of the two
brightest hotspots (A and D). The low-energy portion of the electron
distributions have flat power-law slopes (s~1.5) up to the break energy which
corresponds almost exactly to the mass ratio between protons and electrons; we
argue that these features are most likely intrinsic rather than due to
absorption effects. Beyond the break, the electron spectra continue to higher
energies with very steep slopes s>3. Thus, there is no evidence for the
`canonical' s=2 slope expected in 1st order Fermi-type shocks within the whole
observable electron energy range. We discuss the significance of these
observations and the insight offered into high-energy particle acceleration
processes in mildly relativistic shocks.Comment: 5 pages, 3 figures, in Extragalactic Jets: Theory and Observation
from Radio to Gamma Ray, Eds. T. A. Rector and D. S. De Youn
X-ray Emission Properties of Large Scale Jets, Hotspots and Lobes in Active Galactic Nuclei
We examine a systematic comparison of jet-knots, hotspots and radio lobes
recently observed with Chandra and ASCA. This report will discuss the origin of
their X-ray emissions and investigate the dynamics of the jets. The data was
compiled at well sampled radio (5GHz) and X-ray frequencies (1keV) for more
than 40 radio galaxies. We examined three models for the X-ray production:
synchrotron (SYN), synchrotron self-Compton (SSC) and external Compton on CMB
photons (EC). For the SYN sources -- mostly jet-knots in nearby low-luminosity
radio galaxies -- X-ray photons are produced by ultrarelativistic electrons
with energies 10-100 TeV that must be accelerated in situ. For the other
objects, conservatively classified as SSC or EC sources, a simple formulation
of calculating the ``expected'' X-ray fluxes under an equipartition hypothesis
is presented. We confirmed that the observed X-ray fluxes are close to the
expected ones for non-relativistic emitting plasma velocities in the case of
radio lobes and majority of hotspots, whereas considerable fraction of
jet-knots is too bright at X-rays to be explained in this way. We examined two
possibilities to account for the discrepancy in a framework of the
inverse-Compton model: (1) magnetic field is much smaller than the
equipartition value, and (2) the jets are highly relativistic on kpc/Mpc
scales. We concluded, that if the inverse-Compton model is the case, the X-ray
bright jet-knots are most likely far from the minimum-power condition. We also
briefly discuss the other possibility, namely that the observed X-ray emission
from all of the jet-knots is synchrotron in origin.Comment: 20 pages, 10 figures, accepted for publication in the Astrophysical
Journal, vol.62
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2
The Ras oncogene products regulate the expression of genes in transformed cells, and members of the Ets family of transcription factors have been implicated in this process. To determine which Ets factors are the targets of Ras signaling pathways, the abilities of several Ets factors to activate Ras-responsive enhancer (RRE) reporters in the presence of oncogenic Ras were examined. In transient transfection assay, reporters containing RREs composed of Ets-AP-1 binding sites could be activated 30-fold in NIH 3T3 fibroblasts and 80-fold in the macrophage-like line RAW264 by the combination of Ets1 or Ets2 and Ras but not by several other Ets factors that were tested in the assay. Ets2 and Ras also superactivated an RRE composed of Ets-Ets binding sites, but the Ets-responsive promoter of the c-fms gene was not superactivated. Mutation of a threonine residue to alanine in the conserved amino-terminal regions of Ets1 and Ets2 (threonine 38 and threonine 72, respectively) abrogated the ability of each of these proteins to superactivate reporter gene expression. Phosphoamino acid analysis of radiolabeled Ets2 revealed that Ras induced normally absent threonine-specific phosphorylation of the protein. The Ras-dependent increase in threonine phosphorylation was not observed in Ets2 proteins that had the conserved threonine 72 residue mutated to alanine or serine. These data indicate that Ets1 and Ets2 are specific nuclear targets of Ras signaling events and that phosphorylation of a conserved threonine residue is a necessary molecular component of Ras-mediated activation of these transcription factors
On the Interaction of the PKS B1358-113 Radio Galaxy with the Abell 1836 Cluster
[abridged] Here we present the analysis of multifrequency data gathered for
the FRII radio galaxy PKS B1358-113, hosted in the brightest cluster galaxy of
Abell 1836. The galaxy harbors one of the most massive black holes known to
date and our analysis of the optical data reveals that this black hole is only
weakly active. Based on new Chandra and XMM-Newton X-ray observations and
archival radio data we derive the preferred range for the jet kinetic
luminosity erg s. This is above the values
implied by various scaling relations proposed for radio sources in galaxy
clusters, being instead very close to the maximum jet power allowed for the
given accretion rate. We constrain the radio source lifetime as
Myrs, and the total amount of deposited jet energy \,ergs. The detailed analysis of the X-ray data provides indication for
the presence of a bow-shock driven by the expanding radio lobes into the Abell
1836 cluster environment, with the corresponding Mach number . This,
together with the recently growing evidence that powerful FRII radio galaxies
may not be uncommon in the centers of clusters at higher redshifts, supports
the idea that jet-induced shock heating may indeed play an important role in
shaping the properties of clusters, galaxy groups, and galaxies in formation.
We speculate on a possible bias against detecting jet-driven shocks in poorer
environments, resulting from an inefficient electron heating at the shock
front, combined with a relatively long electron-ion equilibration timescale.Comment: Version accepted to Ap
Ets-2 and Components of Mammalian SWI/SNF Form a Repressor Complex That Negatively Regulates the BRCA1Promoter
Ets-2 is a transcriptional activator that can be modulated by ras-dependent phosphorylation. Evidence is presented indicating that ets-2 can also act as a transcriptional repressor. In the breast cancer cell line MCF-7, exogenous ets-2 repressed the activity of a BRCA1promoter-luciferase reporter dependent on a conserved ets-2-binding site in this promoter. Conditional overproduction of ets-2 in MCF-7 cells resulted in repression of endogenousBRCA1 mRNA expression. To address the mechanism by which ets-2 could act as a repressor, a biochemical approach was used to identify proteins that interacted with the ets-2 pointed domain. From this analysis, components of the mammalian SWI/SNF chromatin remodeling complex were found to interact with ets-2. Brg-1, the ATP-hydrolyzing component of the SWI/SNF complex, along with the BAF57/p50 and Ini1 subunits could be co-immunoprecipitated from cells with ets-2. The pointed domain of ets-2 directly interacted in vitro with the C-terminal region of Brg-1 in a phosphorylation-dependent manner. The combination ofBrg-1 and ets-2 could repress theBRCA1 promoter reporter in transfection assays. These results support a role for ets-2 as a repressor and indicate that components of the mammalian SNF/SWI complex are required as co-repressors
Cosmic ray diffusive acceleration at shock waves with finite upstream and downstream escape boundaries
In the present paper we discuss the modifications introduced into the
first-order Fermi shock acceleration process due to a finite extent of
diffusive regions near the shock or due to boundary conditions leading to an
increased particle escape upstream and/or downstream the shock. In the
considered simple example of the planar shock wave we idealize the escape
phenomenon by imposing a particle escape boundary at some distance from the
shock. Presence of such a boundary (or boundaries) leads to coupled steepening
of the accelerated particle spectrum and decreasing of the acceleration time
scale. It allows for a semi-quantitative evaluation and, in some specific
cases, also for modelling of the observed steep particle spectra as a result of
the first-order Fermi shock acceleration. We also note that the particles close
to the upper energy cut-off are younger than the estimate based on the
respective acceleration time scale. In Appendix A we present a new
time-dependent solution for infinite diffusive regions near the shock allowing
for different constant diffusion coefficients upstream and downstream the
shock.Comment: LaTeX, 14 pages, 4 postscript figures; Solar Physics (accepted
High Energy gamma-rays From FR I Jets
Thanks to Hubble and Chandra telescopes, some of the large scale jets in
extragalactic radio sources are now being observed at optical and X-ray
frequencies. For the FR I objects the synchrotron nature of this emission is
surely established, although a lot of uncertainties - connected for example
with the particle acceleration processes involved - remain. In this paper we
study production of high energy gamma-rays in FR I kiloparsec-scale jets by
inverse-Compton emission of the synchrotron-emitting electrons. We consider
different origin of seed photons contributing to the inverse-Compton
scattering, including nuclear jet radiation as well as ambient, stellar and
circumstellar emission of the host galaxies. We discuss how future detections
or non-detections of the evaluated gamma-ray fluxes can provide constraints on
the unknown large scale jet parameters, i.e. the magnetic field intensity and
the jet Doppler factor. For the nearby sources Centaurus A and M 87, we find
measurable fluxes of TeV photons resulting from synchrotron self-Compton
process and from comptonisation of the galactic photon fields, respectively. In
the case of Centaurus A, we also find a relatively strong emission component
due to comptonisation of the nuclear blazar photons, which could be easily
observed by GLAST at energy ~10 GeV, providing important test for the
unification of FR I sources with BL Lac objects.Comment: 39 pages, 6 figures included. Modified version, accepted for
publication in Astrophysical Journa
INTEGRAL observations of TeV plerions
Amongst the sources seen in very high gamma-rays several are associated with
Pulsar Wind Nebulae (``TeV plerions''). The study of hard X-ray/soft gamma-ray
emission is providing an important insight into the energetic particle
population present in these objects. The unpulsed emission from pulsar/pulsar
wind nebula systems in the energy range accessible to the INTEGRAL satellite is
mainly synchrotron emission from energetic and fast cooling electrons close to
their acceleration site. Our analyses of public INTEGRAL data of known TeV
plerions detected by ground based Cherenkov telescopes indicate a deeper link
between these TeV plerions and INTEGRAL detected pulsar wind nebulae. The newly
discovered TeV plerion in the northern wing of the Kookaburra region
(G313.3+0.6 powered by the middle aged PSR J1420-6048) is found to have a
previously unknown INTEGRAL counterpart which is besides the Vela pulsar the
only middle aged pulsar detected with INTEGRAL. We do not find an INTEGRAL
counterpart of the TeV plerion associated with the X-ray PWN ``Rabbit''
G313.3+0.1 which is possibly powered by a young pulsar.Comment: 4 pages, 6 figures, proceedings of conference "The Multi-Messenger
Approach to High-Energy Gamma-ray Sources" Barcelona/Spain (2006
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