268 research outputs found

    A model of electrical resistivity beneath NE-Iceland, correlation with temperature

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    Short period magnetotelluric measurements (15 s–1 h) were made at 19 sites in NE-Iceland, distributed over the neovolcanic zone and the adjoining older Tertiary flood basalt areas. With model-calculations of one- and two-dimensional resistivity distributions a characteristic model was found for the lower crust and upper mantle. Beneath a thin surface layer the resistivity is 100 Ωm except within the active neovolcanic zone where it is 50 Ωm. This layer extends to a layer with low resistivity of 15 Ωm. The low-resistivity layer is about 5 km thick. The depth of its upper boundary increases from 10 km to about 20 km with increasing distance from the rift axis. The resistivity beneath the low-resistivity layer is about 100 Ωm down to at least 100 km. Comparison of field data with laboratory measurements on conductivity at high temperatures indicates that the low-resistivity layer consists of partially molten basalt at a temperature of 1,000° –1,100° C. The underlying layer very probably consists of partially molten ultramafic rocks and is presumably the uppermost part of the mantle beneath Iceland. The basaltic low-resistivity layer is interpreted as the base of the crust formed by upward movement of the basaltic melt fraction from the mantle.         ARK: https://n2t.net/ark:/88439/y021104 Permalink: https://geophysicsjournal.com/article/77 &nbsp

    The working families' tax credit and some European tax reforms in a collective setting

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    A framework for simplified implementation of the collective model of labor supply decisions is presented in the context of fiscal reforms in the UK. Through its collective form the model accounts for the well known problem of distribution between wallet and purse, a broadly debated issue which has so far been impossible to model due to the limitations of the unitary model of household behavior. A calibrated data set is used to model the effects of introducing two forms of the Working Families’ Tax Credit. We also summarize results of estimations and calibrations obtained using the same methodology on data from five other European countries. The results underline the importance of taking account of the intrahousehold decision process and suggest that who receives government transfers does matter from the point of view of labor supply and welfare of household members. They also highlight the need for more research into models of household behavior

    Assessment of the adaptability of non-fastidious pathogenic bacteria to the Martian environment.

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    Understanding the extent to which non-fastidious pathogenic bacteria can survive in extraterrestrial conditions will help to improve astronaut safety. Despite stringent decontamination protocols, terrestrial microorganisms were previously found to travel on the bodies of astronauts, on spaceships and equipment. This might enable the microorganisms to adapt, grow and evolve in the new environment. In this study, we assessed the adaptability of clinically relevant bacteria species, which are able to grow on carbon-containing compounds identified in carbonaceous meteorites (Klebsiella pneumoniae, Burkholderia cepacia, Serratia marcescens and Pseudomonas aeruginosa), to the simulated Martian environment. Previous work has shown that bacterial survival and growth under these conditions led to the modification of their cell envelope, thereby altering their pathogenic potential. We continued with this line of research and explored the survival of these bacterial species to a range of simulated Martian conditions i.e., desiccation, UVC (254 nm) and polychromatic UV (200 - 400 nm) irradiation, growth in the presence of perchlorates, growth on Martian simulant and exposure to Martian atmospheric composition and pressure. Preliminary results showed that growth was enhanced by the addition of Mars Global simulant (mimicking Martian regolith) to the incubation media. Furthermore, these initial results showed that only two of the strains, K. pneumoniae and S. marcescens are tolerant to desiccation, up to 16 days. The UVC irradiation experiments have shown that the bacteria with the highest degree of survival are P. aeruginosa and S. marcescens. Likewise, the same two strains have shown higher survival rates compared to K. pneumoniae and B. cepacia when exposed to polychromatic UV irradiation. To investigate the consequences of survival and growth under simulated Martian conditions, on virulence and immune recognition, a follow-up study will analyze the response of immune cells placed in contact with bacteria exposed to the Martian environment. In addition, gene expression of the adapted bacteria will be further studied. This collaborative study between the DLR (German Aerospace Center) and the Radboud UMC, in the Netherlands has provided a starting point to the investigation into the adaptability of pathogenic bacteria to Martian conditions. Further studies are required in order to improve our insight on the effects of virulence and immune recognition of the exposed pathogens. This could enable us to potentially anticipate the risks of infection and inflammation during space-travel and exploration

    Cross-sectional observational study of 208 patients with non-classical urea cycle disorders.

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    Urea cycle disorders (UCDs) are inherited disorders of ammonia detoxification often regarded as mainly of relevance to pediatricians. Based on an increasing number of case studies it has become obvious that a significant number of UCD patients are affected by their disease in a non-classical way: presenting outside the newborn period, following a mild course, presenting with unusual clinical features, or asymptomatic patients with only biochemical signs of a UCD. These patients are surviving into adolescence and adulthood, rendering this group of diseases clinically relevant to adult physicians as well as pediatricians. In preparation for an international workshop we collected data on all patients with non-classical UCDs treated by the participants in 20 European metabolic centres. Information was collected on a cohort of 208 patients 50% of which were ≥ 16 years old. The largest subgroup (121 patients) had X-linked ornithine transcarbamylase deficiency (OTCD) of whom 83 were female and 29% of these were asymptomatic. In index patients, there was a mean delay from first symptoms to diagnosis of 1.6 years. Cognitive impairment was present in 36% of all patients including female OTCD patients (in 31%) and those 41 patients identified presymptomatically following positive newborn screening (in 12%). In conclusion, UCD patients with non-classical clinical presentations require the interest and care of adult physicians and have a high risk of neurological complications. To improve the outcome of UCDs, a greater awareness by health professionals of the importance of hyperammonemia and UCDs, and ultimately avoidance of the still long delay to correctly diagnose the patients, is crucial

    Microbial Monitoring in the EDEN ISS Greenhouse, a Mobile Test Facility in Antarctica

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    The EDEN ISS greenhouse, integrated in two joined containers, is a confined mobile test facility in Antarctica for the development and optimization of new plant cultivation techniques for future space programs. The EDEN ISS greenhouse was used successfully from February to November 2018 for fresh food production for the overwintering crew at the Antarctic Neumayer III station. During the 9 months of operation, samples from the different plants, from the nutrition solution of the aeroponic planting system, and from diverse surfaces within the three different compartments of the container were taken [future exploration greenhouse (FEG), service section (SS), and cold porch (CP)]. Quantity as well as diversity of microorganisms was examined by cultivation. In case of the plant samples, microbial quantities were in a range from 102 to 104 colony forming units (CFU) per gram plant material. Compared to plants purchased from a German grocery, the produce hosted orders of magnitude more microorganisms than the EDEN ISS plants. The EDEN ISS plant samples contained mainly fungi and a few bacteria. No classical food associated pathogenic microorganism, like Escherichia and Salmonella, could be found. Probably due to the used cultivation approach, Archaea were not found in the samples. The bioburden in the nutrition solutions increased constantly over time but never reached critical values like 10² –10³ CFU per 100 mL in irrigation water as it is stated, e.g., for commercial European plant productions. The surface samples revealed high differences in the microbial burden between the greenhouse part of the container and the SS and CP part. However, the numbers of organisms (bacteria and fungi) found in the planted greenhouse were still not critical. The microbial loaded surfaces showed strong temporal as well as spatial fluctuations. In samples of the nutrition solution and the surface, the number of bacteria exceeded the amount of fungi by many times. For identification, 16S rRNA gene sequencing was performed for the isolated prokaryotic organisms. Phylogenetic analyses revealed that the most abundant bacterial phyla were Firmicutes and Actinobacteria. These phyla include plant- and human-associated bacterial species. In general, it could be shown that it is possible to produce edible fresh food in a remote environment and this food is safe for consumption from a microbiological point of view
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