Irminger Current Anticyclones in the Labrador Sea observed in the hydrographic record, 1990-2004

Author Posting. © Sears Foundation for Marine Research, 2009. This article is posted here by permission of Sears Foundation for Marine Research for personal use, not for redistribution. The definitive version was published in Journal of Marine Research 67 (2009): 361-384, doi:10.1357/002224009789954739.A significant fraction of the lateral heat transport into the Labrador Sea's interior, needed to balance the net heat loss to the atmosphere, is attributed to the Irminger Current Anticyclones. These mesoscale eddies advect warm, salty boundary current water, of subtropical origin, from the boundary current to the interior— but when or how they release their anomalous heat content has not been previously investigated. In this study, we discuss the seasonal and interannual evolution of these anticyclones as inferred from the analysis of hydrographic data from the Labrador Sea from 1990 to 2004. The 29 identified anticyclones fall into two categories, which we refer to as unconvected and convected. Unconvected anticyclones have properties that are close to those of the boundary current, including a fresh surface layer, and they are found near the boundaries and never observed in winter. Convected anticyclones, on the other hand, contain a mixed layer, lack a freshwater cap and are observed throughout the year. Using a one-dimensional mixing model, it is shown that the convected eddies are those Irminger Current Anticyclones that have been modified by the large winter buoyancy loss of the region. This provides evidence that such eddies can survive the strong winter buoyancy loss in the Labrador Sea and that their anomalous heat and salt content is not trivially mixed into the Sea's interior. Finally, we observe a clear trend in the eddies' properties toward warmer and saltier conditions after 1997 reflecting changes in the source waters and the reduced atmospheric forcing over the Labrador Sea.The work was funded by National Science Foundation grant number OCE-0525929

Problematic aspects of participation of pharmacists in the system of pharmacovigilance in Russia

In article results pharmacoepidemiology researches on studying of knowledge of pharmacists (n=187) on safety issues medicinal and pharmacovigilance are resulted. 28 % of pharmacists have adverse drug reactions to medicines in the practice, however submit spontaneous messages only 5 % of respondents. Princi pal causes of low activity of pharmacists - a lack of time for drawing up of reports and low level of knowledge in the field of safety of medical products. 89 % of pharmacists need educational programs on pharmacovigilanc

Empirical Evaluation of Educational Service Quality in the Current Higher Education System

During the transition to the mixed education model during the Covid-19 pandemic, some issues have emerged in the matter of providing and supporting the quality of university education in all countries, including educational programs' relevance to the demands of the labor market, expectations of students and their families, digital transformation of the educational process, and economic stability of institution networks. The purpose of the research was to evaluate the quality of educational services in the higher education systems of Indonesia and Russia. The study systematized several essential factors for achieving educational service quality in the current higher education systems, given the limitations imposed by Covid-19. Following this objective, the study utilized a quantitative approach, adopting the SERVQUALmodel that measures the service quality across five service dimensions: tangibility, reliability, responsiveness, assurance, and empathy. The model aided the development of the questionnaire to assess the quality of the educational services of Indonesian and Russian universities. The questionnaire included 25 close-ended questions on two scales: one to measure the students' expectations regarding the quality of educational services and the other to measure the students' current perceptions. A snowball technique was used to recruit students from Indonesian and Russian universities as participants in the study. The students were asked to assess the educational services of their universities based on their initial expectations and current perceptions. Overall, the students of both countries revealed that they had high expectations from the educational services of their universities. However, the current perceptions of the Russian students regarding the quality of educational services provided by their universities are higher and more positive than the perceptions of the Indonesian students regarding the quality of educational services being delivered to them. The findings of the study have implications for education practitioners. Doi: 10.28991/ESJ-2022-SIED-05 Full Text: PD

Study of the influence of nutrition factors on the physical development of preschool children

The article presents the results of a comprehensive assessment of the physical development of preschool children (6-7 years old) and their relationship with nutrition in a preschool educational organization. For a complete analysis, an additional survey of parents was conducted. During the study, it became known that children are overweight, there are disorders of the musculoskeletal system and oral hygiene.В статье представлены результаты комплексной оценки физического развития детей дошкольного возраста (6-7лет) и взаимосвязь их с питанием в дошкольной образовательной организации. Для полного анализа дополнительно проведено анкетирование родителей. В ходе исследования стало известно, что у детей наблюдается избыточная масса тела, есть нарушения со стороны костно-мышечного аппаратаивыявлены заболевания полости рта

Cell-free and cell-bound circulating DNA in breast tumours: DNA quantification and analysis of tumour-related gene methylation

Tumour development is characterised by the increased circulating DNA (cirDNA) concentration and by tumour-related changes in blood plasma DNA. Concentration of cirDNA and methylation of RARβ2, RASSF1A and HIC-1 gene promoters were investigated in cell-free and cell-surface-bound fractions from healthy donors, patients with breast cancer, and patients with breast fibroadenoma. Tumour development was shown to lead to significant changes in the distribution of cirDNA between cell-free and cell-surface-bound fractions. Analysis of RARβ2 and RASSF1A methylation in the total cirDNA provides 95% diagnostic coverage in breast cancer patients, 60% in patients with benign lesions, and is without false-positive results in healthy women. Results of the study indicate that methylation-specific PCR of RARβ2 and RASSF1A genes based on the total cirDNA combined with the quantitative analysis of cirDNA distribution between cell-bound and cell-free fractions in blood provide the sensitive and accurate detection and discrimination of malignant and benign breast tumours

On the professional risk of the development of dust pathology in workers of copper smelting production

The article assesses the risk of developing dust pathology and occupational morbidity among workers employed in the electrolytic production of copper.Пылевая патология имеет широкое распространение при получении меди. В статье оценивается риск развития пылевой патологии и профессиональная заболеваемость среди рабочих, занятых в получении меди

On the professional risk of the development of dust pathology in workers of copper smelting production

The article assesses the risk of developing dust pathology and occupational morbidity among workers employed in the electrolytic production of copper.Пылевая патология имеет широкое распространение при получении меди. В статье оценивается риск развития пылевой патологии и профессиональная заболеваемость среди рабочих, занятых в получении меди

Particular Characterisation of an In-Vitro-DTH Test to Monitor Cellular Immunity - Applications for Patient Care and Space Flight

Goal:i) Characterization of the role of the main immune reactive cell types contributing to the cellular immune response in the in-vitro DTH and ii) Validation of the in-vitro DTH under different clinical and field conditions. Methods:As positive control whole blood was incubated in the in-vitro DTH, supernatants were gathered after 12, 24 and 48h. Readout parameters of this test are cytokines in the assay's supernatant. To determine the role of T-cells, monocytes and natural killer (NK), these cell populations were depleted using magnetic beads prior to in-vitro-DTH incubation. Validation of the test has occurred under clinical (HIV-patients, ICU) and field-conditions (parabolic/space-flights, confinement). Results:T-cell depletion abandoned almost any IL-2 production and reduced IFN-gamma production irrespective of the type of antigen, whereas CD56 depleted cultures tended to lower IL-2 secretion and IFN-gamma and to parallel a IL-10-increase after viral challenge. This IL-10-increase was seen also in CD14-depleted setups. DTH read-out was significantly different under acute stress (parabolic flight) or chronic stress (ISS), respectively. Preliminary data of HIV infected patients demonstrate that this test can display the contemporary immune status during an antiviral therapy. Conclusion:The in-vitro DTH mirrors adaptive and innate immune activation and may serve as tool also for longitudinal follow up of Th1/Th2 weighed immune response under adverse life conditions on earth and in space. It is planned to implement the assay in the on the ISS (MoCISS)

Crystalline Structure of Potassium Holmium Double Tungstate

The potassium holmium double tungstate was prepared by using top seeded solution growth technique. Structural investigations have been performed at room temperature. The KHo(WO4)2 single crystal belongs to the monoclinic space group C2/c with the unit-cell parameters: a = 10.624(2) Å, b = 10.352(2) Å, c = 7.5434(15) Å, β = 130.7