Gambaran Kejadian Dermatitis Pada Tenaga Kerja Indonesia Di Tempat Penampungan Sementara Di Kabupaten Nunukan

Dermatitis is inflammation of the skin as a response against the influence of exogenous or endogenous factors that cause clinical disorders such asefloresensi polymorphic and complaints of itching. Data from Tarakan KKP working area Nunukan in 2015, the prevalence of dermatitis 53.2% of cases.This study aims to describe the incidence of dermatitis on migrant workers at the polling station in Nunukan. This type of research is descriptive with cross sectional design. The population in this study are all workers who are in the polling stations outpatient treatment Polyclinic Tarakan KKP working area Nunukan in september 2016 total 105 people with simple random sampling method sampling.Analysis of the data used areunivariate in the form distribution frequency table accompanied by narration.The results of this study found depiction of the incidence of dermatitis on migrant workers (64.8%) and, not dermatitis (35.2%). The incidence of dermatitis is dominated by age group ≥30 years (60.7%). The majority are those with history of skin diseases (84.2%) and had poor water quality (84.5%). The intensity of the shower bath is dominated by less than 2 times a day (85.3%), baths use rainwater (83.0%) and those who did not shower after work or sports (78.6%). the cleanliness of the clothes dominated by the change of clothes for less than 2 times a day (78.3%), did not iron clothes before use (65.4%), soak the clothes mixed with clothes friends (80.4%) and washes the clothes in a public toilet using rain water (65.3%)all of that included in the category of bad. It is expected to health workers to conduct socialization ofhygiene and health behaviorsin order to overcome the incidence of dermatitis andto the migrant workers, to always maintain personal hygiene and the cleanliness of clothes,as well as increasing proper bathing habits

Sodium benzoate and potassium sorbate preservatives in food stuffs in Iran

A high-performance liquid chromatography method was applied for the determination of the levels of benzoate and sorbate in 400 food samples, including pickled cucumbers, canned tomato pastes, sour cherry jams, soft drinks, fruit juices and dairy products (UF-Feta cheeses, Lighvan cheeses, lactic cheeses, yogurts and doogh). The results showed that 270 (67.5%) of all samples contained benzoate ranging from 11.9 to 288.5 mg kg⁻¹ in lactic cheese and fruit juice, respectively. The levels of sorbate in 98 (24.5%) of the samples were 20.1 to 284.3 mg kg⁻¹ in doogh and fruit juice, respectively. Moreover, benzoate was detected in all dairy products ranging from 11.9 mg kg⁻¹ in lactic cheese to 91.2 mg kg⁻¹ in UF-Feta cheese. A low concentration of benzoate could originate naturally, due to specific biochemical mechanisms during cheese, yogurt and doogh maturation. In conclusion, a minimum level for benzoate in dairy products should be defined in the legislation. © 2015 Taylor & Francis

Faktor Risiko Kejadian Katarak pada Pasien Pria Usia 40-55 Tahun Dirumah Sakit Pertamina Balikpapan

Katarak terjdi akibat kekeruhan pada lensa mata yang mengakibatkan tergantungnya cahaya masuk ke dalam bola mata, sehingga penglihatan menjadi kabur dan lama kelamaan dapat menyebabkan kebutaan. Salah satu penyebab kebutaan terbanyak di seluruh dunia adalah katarak. Peningkatan kasus kejadian katarak terjadi di Rumah Sakit Pertamina Balikpapan selama 3 bulan terakhir pada bulan Januari hingga Maret yaitu 142 kasus, 173 kasus dan 188 kasus. Kejadian katarak berhubungan dengan penyebab diabetes mellitus, status ekonomi, kebiasaan merokok, pekerjaan terpapar UV, dan kebiasaan konsumsi protein. Tujuan penelitian ini adalah untuk menganalisis besarnya faktor risiko dengan kejadian katarak pada pasien pria usia 40-55 tahun di rumah sakit pertamina Balikpapan. Jenis penelitian yang digunakan dalam penelitian ini adalah studi observasional analitik dengan desain case control study. Sampel pada penelitian ini terdiri dari kasus dan control dengan menggunakan metode Purposive Sampling, sampel kasus yakni pasien pria usia 40-55 katarak yang berobat maupun screening di Rumah Sakit Pertamina Balikpapan Tahun 2017. Sampel kontrol penelitian ini adalah pasien pria usia 40-55 yang tidak menderita katarak yang berobat maupun screening di Rumah Sakit Pertamina Balikpapan Tahun 2017. Hasil penelitian menunjukkan bahwa diabetes mellitus (OR=4.419;95%Cl:1,991-9,809), Status ekonomi (OR=2.852;95%Cl:1,346-6,042), Kebiasaan merokok (OR=3,850; 95%Cl:1,785-8,304), Pekerjaan terpapar UV (OR=3.217; 95%Cl:1.523-6.795) merupakan faktor risiko terhadap kejadian Katarak. Sedangkan Konsumsi protein (OR=0.110; 95%Cl:0,046-0,264) merupakan faktor protektif kejadian katarak. Berdasarkan analisis multivariat menemukan bahwa Faktor risiko yang paling berpengaruh yaitu diabetes mellitus (p = 0,000) dan pekerjaan terpapar UV (p =0,001) terhadap kejadian katarak

Coronary Heart Disease Risk Factors Among Women Aged Older Than 45 Years Old in Makassar

Cardiovascular disease causes 8.6 million deaths of women every year, which is the major cause of death by one-third of all deaths of women in the world. Half of all deaths of women older than 50 years old is caused by cardiovascular and stroke diseases. This study aimed to analyze risk factors related to coronary heart disease among women aged older than 45 years at Dody Sarjoto Makassar Air Force Hospital 2016. The total of sample was 76 consisting of 64 cases of coronary heart disease and 12 non-coronary heart disease. Determination of sample used purposive sampling. Primary data were obtained through interview to respondents using questionnaire and direct interview. Data were analyzed by using contingency correlation coefficient (Exp (B)) test to identify significant relation between dependent and independent variables. Results found were hypertension (Exp (B) = 0.309), obesity (Exp (B) = 0.140), diabetes mellitus (Exp (B) = 0.164) and dyslipidemia (Exp (B) = 0.185), as proven having relation with coronary heart disease among women aged older than 45 years, and the factor which had the most significant relation was dyslipidemia

Kajian Kerentanan pada Sektor Konstruksi dalam Pengurangan Risiko Bencana Gempa Bumi

Ancaman bencana dikombinasikan dengan pertumbuhan di sektor konstruksi menimbulkan permasalahan kerentanan bangunan. Hal ini ditandai dengan meningkatnya jumlah dan skala kerusakan akibat bencana., khususnya bencana akibat gempa bumi. Cara membangun yang salah, baik dari segi perencanaan dan perancangan maupun dari segi pelaksanaan dan pengawasannya dapat menghasilkan infrastruktur yang rentan terhadap bencana. Penulisan ini adalah hasil dari penelitian pendahuluan disertasi, berupa identifikasi kerentanan mulai dari tahap gagasan sampai dengan operasional dan perawatan. Metode identifikasi kerentanan menggunakan teknik Delphi, yaitu melalui kuisioner yang dilakukan secara langsung maupun menggunakan media internet (via email), verifikasi dilakukan melalui wawancara mendalam secara berulang (iterasi) dan validasi dengan pendekatan FGD yang diwakili oleh stakeholder pada sektor konstruksi. Hasil penelitian menunjukkan bahwa potensi kegagalan dapat terjadi pada tahapan-tahapan konstruksi melalui tinjauan aspek teknis, sosial budaya, politik dan ekonomi, diharapkan hasil penelitian dapat dikembangkan untuk membangun konstruksi Indonesia agar mampu berperan positif dalam mengurangi risiko bencana dan berkontribusi positif terhadap seluruh upaya penanggulangan bencana di Indonesi

Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics

BACKGROUND: Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing. Recently however, actively transcribed genes have also been found localized to the nuclear periphery in the yeast Saccharomyces cerevisiae. When genes are activated, they become associated with the nuclear pore complex (NPC) at the nuclear envelope. Furthermore, chromosomes are not static structures, but exhibit constrained diffusion in real-time, live-cell studies of particular loci. The relationship of chromosome motion with transcriptional activation and active-gene recruitment to the nuclear periphery has not yet been investigated. RESULTS: We have generated a yeast strain that enables us to observe the motion of the galactose-inducible GAL gene locus relative to the nuclear periphery in real-time under transcriptionally active and repressed conditions. Using segmented geometric particle tracking, we show that the repressed GAL locus undergoes constrained diffusive movement, and that transcriptional induction with galactose is associated with an enrichment in cells with GAL loci that are both associated with the nuclear periphery and much more constrained in their movement. Furthermore, we report that the mRNA export factor Sac3 is involved in this galactose-induced enrichment of GAL loci at the nuclear periphery. In parallel, using a novel machine visual screening technique, we find that the motion of constrained GAL loci correlates with the motion of the cognate nuclei in galactose-induced cells. CONCLUSION: Transcriptional activation of the GAL genes is associated with their tethering and motion constraint at the nuclear periphery. We describe a model of gene recruitment to the nuclear periphery involving gene diffusion and the mRNA export factor Sac3 that can be used as a framework for further experimentation. In addition, we applied to the analysis of chromosome motion a machine visual screening approach that used unbiased visual data rather than segmented geometric data. This novel analytical approach will allow for high-throughput study of processes that can be monitored via alterations in chromosome motion and connectivity with the nuclear periphery

Assumptions of the primordial spectrum and cosmological parameter estimation

The observables of the perturbed universe, CMB anisotropy and large structures, depend on a set of cosmological parameters, as well as, the assumed nature of primordial perturbations. In particular, the shape of the primordial power spectrum (PPS) is, at best, a well motivated assumption. It is known that the assumed functional form of the PPS in cosmological parameter estimation can affect the best fit parameters and their relative confidence limits. In this paper, we demonstrate that a specific assumed form actually drives the best fit parameters into distinct basins of likelihood in the space of cosmological parameters where the likelihood resists improvement via modifications to the PPS. The regions where considerably better likelihoods are obtained allowing free form PPS lie outside these basins. In the absence of a preferred model of inflation, this raises a concern that current cosmological parameters estimates are strongly prejudiced by the assumed form of PPS. Our results strongly motivate approaches toward simultaneous estimation of the cosmological parameters and the shape of the primordial spectrum from upcoming cosmological data. It is equally important for theorists to keep an open mind towards early universe scenarios that produce features in the PPS.Comment: 11 pages, 2 figures, discussions extended, main results unchanged, matches published versio

Rod photoreceptors drive circadian photoentrainment across a wide range of light intensities.

In mammals, synchronization of the circadian pacemaker in the hypothalamus is achieved through direct input from the eyes conveyed by intrinsically photosensitive retinal ganglion cells (ipRGCs). Circadian photoentrainment can be maintained by rod and cone photoreceptors, but their functional contributions and their retinal circuits that impinge on ipRGCs are not well understood. Using mice that lack functional rods or in which rods are the only functional photoreceptors, we found that rods were solely responsible for photoentrainment at scotopic light intensities. Rods were also capable of driving circadian photoentrainment at photopic intensities at which they were incapable of supporting a visually guided behavior. Using mice in which cone photoreceptors were ablated, we found that rods signal through cones at high light intensities, but not at low light intensities. Thus, rods use two distinct retinal circuits to drive ipRGC function to support circadian photoentrainment across a wide range of light intensities