Exactly solvable model of wormhole supported by phantom energy

We have found a simple exact solution of spherically-symmetrical Einstein equations describing a wormhole for an inhomogeneous distribution of the phantom energy. The equation of state is linear but highly anisotropic: while the radial pressure is negative, the transversal one is positive. At infinity the spacetime is not asymptotically flat and possesses on each side of the bridge a regular cosmological Killing horizon with an infinite area, impenetrable for any particles. This horizon does not arise if the wormhole region is glued to the Schwarzschild region. In doing so, the wormhole can enclose an arbitrary amount of the phantom energy. The configuration under discussion has a limit in which the phantom energy turns into the string dust, the areal radius tends to the constant. In this limit, the strong gravitational mass defect is realized in that the gravitational active mass is finite and constant while the proper mass integrated over the total manifold is infinite.Comment: 6 pages. Two references added, typos corrected. Accepted for publication in Phys. Rev. D as Rapid Communicatio

Generalized Swiss-cheese cosmologies: Mass scales

We generalize the Swiss-cheese cosmologies so as to include nonzero linear momenta of the associated boundary surfaces. The evolution of mass scales in these generalized cosmologies is studied for a variety of models for the background without having to specify any details within the local inhomogeneities. We find that the final effective gravitational mass and size of the evolving inhomogeneities depends on their linear momenta but these properties are essentially unaffected by the details of the background model.Comment: 10 pages, 14 figures, 1 table, revtex4, Published form (with minor corrections

The standard "static" spherically symmetric ansatz with perfect fluid source revisited

Considering the standard "static" spherically symmetric ansatz ds2 = -B(r) dt2 + A(r) dr2 + r2 dOmega2 for Einstein's Equations with perfect fluid source, we ask how we can interpret solutions where A(r) and B(r) are not positive, as they must be for the static matter source interpretation to be valid. Noting that the requirement of Lorentzian signature implies A(r) B(r) >0, we find two possible interpretations: (i) The nonzero component of the source four-velocity does not have to be u0. This provides a connection from the above ansatz to the Kantowski-Sachs (KS) spacetimes. (ii) Regions with negative A(r) and B(r) of "static" solutions in the literature must be interpreted as corresponding to tachyonic source. The combinations of source type and four-velocity direction result in four possible cases. One is the standard case, one is identical to the KS case, and two are tachyonic. The dynamic tachyonic case was anticipated in the literature, but the static tachyonic case seems to be new. We derive Oppenheimer-Volkoff-like equations for each case, and find some simple solutions. We conclude that new "simple" black hole solutions of the above form, supported by a perfect fluid, do not exist.Comment: 24 standard LaTeX pages, no figures. Some change in emphasis; changes in parametrizations of some of the solutions (ND2, TD2, TD3, NS1); one new solution (TS4); removal of an incorrect statement (about ND4

Static charged perfect fluid spheres in general relativity

Interior perfect fluid solutions for the Reissner-Nordstrom metric are studied on the basis of a new classification scheme. General formulas are found in many cases. Explicit new global solutions are given as illustrations. Known solutions are briefly reviewed.Comment: 23 pages, Revtex (galley), journal version, to appear in Phys.Rev.

Analysis of high-identity segmental duplications in the grapevine genome

<p>Abstract</p> <p>Background</p> <p>Segmental duplications (SDs) are blocks of genomic sequence of 1-200 kb that map to different loci in a genome and share a sequence identity > 90%. SDs show at the sequence level the same characteristics as other regions of the human genome: they contain both high-copy repeats and gene sequences. SDs play an important role in genome plasticity by creating new genes and modeling genome structure. Although data is plentiful for mammals, not much was known about the representation of SDs in plant genomes. In this regard, we performed a genome-wide analysis of high-identity SDs on the sequenced grapevine (<it>Vitis vinifera</it>) genome (PN40024).</p> <p>Results</p> <p>We demonstrate that recent SDs (> 94% identity and >= 10 kb in size) are a relevant component of the grapevine genome (85 Mb, 17% of the genome sequence). We detected mitochondrial and plastid DNA and genes (10% of gene annotation) in segmentally duplicated regions of the nuclear genome. In particular, the nine highest copy number genes have a copy in either or both organelle genomes. Further we showed that several duplicated genes take part in the biosynthesis of compounds involved in plant response to environmental stress.</p> <p>Conclusions</p> <p>These data show the great influence of SDs and organelle DNA transfers in modeling the <it>Vitis vinifera </it>nuclear DNA structure as well as the impact of SDs in contributing to the adaptive capacity of grapevine and the nutritional content of grape products through genome variation. This study represents a step forward in the full characterization of duplicated genes important for grapevine cultural needs and human health.</p

The PI3K/Akt1 pathway enhances steady-state levels of FANCL

Fanconi anemia hematopoietic stem cells display poor self-renewal capacity when subjected to a variety of cellular stress. This phenotype raises the question of whether the Fanconi anemia proteins are stabilized or recruited as part of a stress response and protect against stem cell loss. Here we provide evidence that FANCL, the E3 ubiquitin ligase of the Fanconi anemia pathway, is constitutively targeted for degradation by the proteasome. We confirm biochemically that FANCL is polyubiquitinated with Lys-48-linked chains. Evaluation of a series of N-terminal-deletion mutants showed that FANCL's E2-like fold may direct ubiquitination. In addition, our studies showed that FANCL is stabilized in a complex with axin1 when glycogen synthase kinase-3β is overexpressed. This result leads us to investigate the potential regulation of FANCL by upstream signaling pathways known to regulate glycogen synthase kinase-3β. We report that constitutively active, myristoylated-Akt increases FANCL protein level by reducing polyubiquitination of FANCL. Two-dimensional PAGE analysis shows that acidic forms of FANCL, some of which are phospho-FANCL, are not subject to polyubiquitination. These results indicate that a signal transduction pathway involved in self-renewal and survival of hematopoietic stem cells also functions to stabilize FANCL and suggests that FANCL participates directly in support of stem cell function

DE SITTER METRIC WITH MAGNETIC FIELD

De Sitter model with magnetic field was considered. The exact solution was obtained. The properties of the model in comparison with empty de Sitter model were analyzed

The Models of Voids in the Friedman Universe

The astronomical observations of the last years show that there are the regions in the Universe with much lower density of matter, than their surroundings. Theoretical studies of the regions (voids) in the model of the expanding Universe are carried on different directions. In this paper the voids have been built by means of matching Tolman and Friedman solutions. The Lichnerovich-Darmois matching conditions are used. It is shown that in expanding Universe with at space the voids can not exist. So we have Friedman Universe with voids, with described by the Tolman solution. The models of voids in the Friedman Universe with negative spatial curvature have been built