7,023 research outputs found
Dual enhancement mechanisms for overnight motor memory consolidation
Our brains are constantly processing past events<sup>1</sup>. These offline processes consolidate memories, leading in the case of motor skill memories to an enhancement in performance between training sessions. A similar magnitude of enhancement develops over a night of sleep following an implicit task, in which a sequence of movements is acquired unintentionally, or following an explicit task, in which the same sequence is acquired intentionally<sup>2</sup>. What remains poorly understood, however, is whether these similar offline improvements are supported by similar circuits, or through distinct circuits. We set out to distinguish between these possibilities by applying transcranial magnetic stimulation over the primary motor cortex (M1) or the inferior parietal lobule (IPL) immediately after learning in either the explicit or implicit task. These brain areas have both been implicated in encoding aspects of a motor sequence and subsequently supporting offline improvements over sleep<sup>3,4,5</sup>. Here we show that offline improvements following the explicit task are dependent on a circuit that includes M1 but not IPL. In contrast, offline improvements following the implicit task are dependent on a circuit that includes IPL but not M1. Our work establishes the critical contribution made by M1 and IPL circuits to offline memory processing, and reveals that distinct circuits support similar offline improvements
Memory processing: the critical role of neuronal replay during sleep
Patterns of neuronal activity present during learning in the hippocampus are replayed during sleep. A new study highlights the functional importance of this neurophysiological phenomenon by showing that neuronal replay is critical for memory processing over a night of sleep
The long-term evolution of the X-ray pulsar XTE J1814-338: a receding jet contribution to the quiescent optical emission?
We present a study of the quiescent optical counterpart of the Accreting
Millisecond X-ray Pulsar XTE J1814-338, carrying out multiband (BVR) orbital
phase-resolved photometry using the ESO VLT/FORS2. The optical light curves are
consistent with a sinusoidal variability modulated with the orbital period,
showing evidence for a strongly irradiated companion star, in agreement with
previous findings. The observed colours cannot be accounted for by the
companion star alone, suggesting the presence of an accretion disc during
quiescence. The system is fainter in all analysed bands compared to previous
observations. The R band light curve displays a possible phase offset with
respect to the B and V band. Through a combined fit of the multi-band light
curves we derive constraints on the companion star and disc fluxes, on the
system distance and on the companion star mass. The irradiation luminosity
required to account for the observed day-side temperature of the companion star
is consistent with the spin-down luminosity of a millisecond radio pulsar. The
flux decrease and spectral evolution of the quiescent optical emission observed
comparing our data with previous observations, collected over 5 years, cannot
be well explained with the contribution of an irradiated companion star and an
accretion disc alone. The progressive flux decrease as the system gets bluer
could be due to a continuum component evolving towards a lower, bluer spectrum.
While most of the continuum component is likely due to the disc, we do not
expect it to become bluer in quiescence. Hence we hypothesize that an
additional component, such as synchrotron emission from a jet was contributing
significantly in the earlier data obtained during quiescence and then
progressively fading or moving its break frequency toward longer wavelengths.Comment: 7 pages, 8 figures, accepted for publication in Section 7. Stellar
structure and evolution of Astronomy and Astrophysic
Properties of the redback millisecond pulsar binary 3FGL J0212.1+5320
Linares et al. (2016) obtained quasi-simultaneous g', r' and i-band light
curves and an absorption line radial velocity curve of the secondary star in
the redback system 3FGL J0212.1+5320. The light curves showed two maxima and
minima primarily due to the secondary star's ellipsoidal modulation, but with
unequal maxima and minima. We fit these light curves and radial velocities with
our X-ray binary model including either a dark solar-type star spot or a hot
spot due to off-centre heating from an intrabinary shock, to account for the
unequal maxima. Both models give a radial velocity semi-amplitude and
rotational broadening that agree with the observations. The observed secondary
star's effective temperature is best matched with the value obtained using the
hot spot model, which gives a neutron star and secondary star mass of =1.85 and =0.50
, respectively.Comment: 10 pages, 8 figues, accepted by MNRA
Observations of Doppler Boosting in Kepler Lightcurves
Among the initial results from Kepler were two striking lightcurves, for KOI
74 and KOI 81, in which the relative depths of the primary and secondary
eclipses showed that the more compact, less luminous object was hotter than its
stellar host. That result became particularly intriguing because a substellar
mass had been derived for the secondary in KOI 74, which would make the high
temperature challenging to explain; in KOI 81, the mass range for the companion
was also reported to be consistent with a substellar object. We re-analyze the
Kepler data and demonstrate that both companions are likely to be white dwarfs.
We also find that the photometric data for KOI 74 show a modulation in
brightness as the more luminous star orbits, due to Doppler boosting. The
magnitude of the effect is sufficiently large that we can use it to infer a
radial velocity amplitude accurate to 1 km/s. As far as we are aware, this is
the first time a radial-velocity curve has been measured photometrically.
Combining our velocity amplitude with the inclination and primary mass derived
from the eclipses and primary spectral type, we infer a secondary mass of
0.22+/-0.03 Msun. We use our estimates to consider the likely evolutionary
paths and mass-transfer episodes of these binary systems.Comment: 8 pages, 4 figures, ApJ 715, 51 (v4 is updated to match the published
version, including a note added in proof with measured projected rotational
velocities)
Grid Added Value to Address Malaria
Through this paper, we call for a distributed, internet-based collaboration
to address one of the worst plagues of our present world, malaria. The spirit
is a non-proprietary peer-production of information-embedding goods. And we
propose to use the grid technology to enable such a world wide "open source"
like collaboration. The first step towards this vision has been achieved during
the summer on the EGEE grid infrastructure where 46 million ligands were docked
for a total amount of 80 CPU years in 6 weeks in the quest for new drugs.Comment: 7 pages, 1 figure, 6th IEEE International Symposium on Cluster
Computing and the Grid, Singapore, 16-19 may 2006, to appear in the
proceeding
- …