Automated Mobility and Orientation System for Blind Person

This paper is intended to provide a model for object detection and real time assistance via Global Positioning System (GPS).This paper aims at the development of an Electronic Travelling Aid (ETA) kit to help the blind people to find obstacle free path. This ETA is fixed to the wheel chair. When the object is detected near to the blind it alerts them with the help of voice play talkto which speakers are connected . Ultrasonic sensors are used to evaluate distance of the objects around the blind person and to guide the user towards the secure and available path. The hardware of entire system contains ARM7 (LPC2148),ultrasonic sensors and voice input kit, speakers, Global positioning system (GPS) module and Global System for Mobile (GSM) modul

Orientation System for Blind Person

This paper is intended to provide a model for object detection and assistance system via Global Positioning System (GPS).This paper provide the development of an Electronic Travelling Aid (ETA) kit to help the blind people to find obstacle free path. This ETA is fixed to the wheel chair. When the object is detected near to the blind it alerts them with the help of voice play talk kit to which speakers are connected . Ultrasonic sensors are used to evaluate distance of the objects around the blind person and to guide the user towards the secure path. The hardware of entire system contains ARM7 (LPC2148),ultrasonic sensors and voice input kit, speakers, Global positioning system (GPS) module and Global System for Mobile (GSM) modul

Effectiveness of structured teaching programme regarding knowledge about uses of menstrual cup among nursing students

Background: Menstruation is a normal biological process experienced by millions of women around the world each month. Good menstrual hygiene practices can prevent infections among women. During menstruation women are using different sanitary products like reusable cloth pads, commercial sanitary pads, tampons, pads made from wool, reusable tampons, and menstrual cups. The menstrual cup was developed as an alternative of sanitary napkins and eco-friendly sanitary product but due to lack of awareness in India it’s uses are very limited. Methods: Quasi experimental one group pre-test and post-test research design was used in this research study. A total 201 nursing students of were selected by using purposive sampling technique. After the pretest structured teaching programme regarding knowledge of menstrual cap uses was implemented among nursing students and on 10th day of STP post-test was done by using the same tools. Results: During the pre-test researcher found that majority (81.59%) of nursing students had inadequate knowledge regarding menstrual cups uses. The mean knowledge score was significantly (p<0.05) increases from pre-test (7±3.06) to post-test (15±2.36) where mean difference was 8. Conclusions: The study results highlighted that the STP was highly effective in increase the knowledge among nursing students. Educational intervention programs must give importance in Professional Institutions, which will motivate female’s students to start practice of menstrual cups during menstruation. This is eco-friendly initiative

QUANTIFICATION OF PHYTOCHEMICAL CONTENTS AND IN VITRO ANTIOXIDANT ACTIVITY OF EXACUM BICOLOR (ROXB.), AN ENDEMIC MEDICINAL PLANT

Objective: To investigate different phytochemical contents and screening of antioxidant activity of sequentially extracted Exacum bicolor leaf with different solvents.Methods: Leaf samples of E. bicolor were dried and subjected to sequential (hexane>chloroform>ethyl acetate>methanol>water) extraction using soxhlet apparatus. Total phenol contents (TPC) were estimated using Folin-ciocalteau method, flavonoids by aluminium chloride method, tannins by Folin-Denis reagent and alkaloids using bromocresol blue. In vitro antioxidant activities were estimated by using 1,1-Diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid ABTS·+and Nitric oxide (NO) scavenging assay.Results: The total phenol, tannin and alkaloid contents in methanol extract were found to be 23.4±0.09 mg GAE/g, 23±0.57 mg TAE/g and 47.33±1.20 mg AE/g respectively. Hexane extract exhibited high flavonoid content (27.6±0.88 mg QE/g). Methanolic extracts exhibited dose dependent antioxidant activity against DPPH, ABTS·+and NO Scavenging methods; low IC50 value (14.84 µg/ml) was observed in DPPH scavenging activity. Findings showed positive and significant (P ≤ 0.05) correlation between TPC/DPPH (R2= 0.98).Conclusions: The methanol extract showed higher antioxidative activity compared to other extracts. Positive correlation was obtained between TPC and DPPH activity signifying that the phenolic content may be responsible for the antioxidant activity of the plant. Further bioassay-guided purification of the bioactive compound is necessary. To the best of our knowledge, antioxidant activity and its correlation with TPC, is reported for the first time in E. bicolor.Â

Potential anti-seizure activity of atorvastatin in rat models of seizure

Background: Atorvastatin belongs to the class of Hypolipidemic statins. Increasing evidence indicates that statins are neuroprotective in several conditions, including stroke, cerebral ischemia and traumatic brain injury. However, only scanty and controversial reports are available on anticonvulsant action of statins. The present study therefore aims at exploring the influence of atorvastatin on seizures as compared to standard anticonvulsants phenytoin and sodium valproate in Wistar rats.Methods: Rats were divided into 8 groups (n=6), each treated intraperitoneally (i.p) with atorvastatin, phenytoin or sodium valproate in their therapeutic equivalent doses. Their effects were evaluated on seizures induced by maximum electroshock seizure (MES) and pentylenetetrazole (PTZ). Hind limb extension (HLE) in MES model, number of seizures, duration of seizure, number of myoclonic jerks and time for onset as well as recovery from seizures in PTZ model were monitored. Statistical analysis was done using Kruskal-Wallis ANOVA and Mann-Whitney U test for significance.Results: Atorvastatin failed to protect rats against HLE in MES seizure model. However, atorvastatin significantly prolonged seizure onset time (p<0.0547), decreased seizure number (p<0.0082), seizure duration (p<0.0547) and recovery time (p<0.0040) in PTZ model indicating its potential antiepileptic activity in PTZ model.Conclusions: Atorvastatin exhibited protection against seizures only in PTZ seizure model. Hence, it could possess anti absence seizure activity. This needs to be established with further systematic animal and clinical studies

Considering Two Sides of One Review Using Stanford NLP Framework

Sentiment analysis is a type of natural language processing for tracking the mood of the public about a particular product or a topic and is useful in several ways. Polarity shift is the most classical task which aims at classifying the reviews either positive or negative. But in many cases, in addition to the positive and negative reviews, there still many neutral reviews exist. However, the performance sometimes limited due to the fundamental deficiencies in handling the polarity shift problem. We propose an Improvised Dual Sentiment Analysis (IDSA) model to address this problem for sentiment classification. We first propose a novel data expansion technique by creating sentiment-reversed review for each training and test review. We develop a corpus based method to construct a pseudo-antonym dictionary. It removes DSA’s dependency on an external antonym dictionary for review reversion. We conduct a range of experiments and the results demonstrates the effectiveness of DSA in addressing the polarity shift in sentiment classification.

CLINICAL FEATURES AND ANTIMICROBIAL SUSCEPTIBILITIES OF ELIZABETHKINGIA MENINGOSEPTICA - AN EMERGING PATHOGEN FROM A TERTIARY CARE HOSPITAL IN MANGALORE

Objectives: Elizabethkingia meningoseptica has been known to infect the immunocompromised, preterm children, those exposed to antibiotics in critical care units, and those with comorbidities. Multidrug resistance seen in E. meningoseptica makes it daunting to choose the right antimicrobial agents for treating infections caused by this organism. The present study was undertaken to establish the incidence of E. meningoseptica infections, to investigate the clinical features and risk factors associated with these infections, and to study the antimicrobial susceptibility pattern of E. meningoseptica isolates over 2 years.Methods: Medical records of the patient positive for E. meningoseptica from January 2015 to December 2016 were studied retrospectively. The demographic and clinical data of the patients and the antibiotic sensitivity patterns were collected and analyzed.Results: E. meningoseptica was isolated from 13 patients. The mean age was 71.09 years with males being more frequently infected (81.8%). Maximum isolates were from blood (38.5%) with sepsis being the final diagnosis in 53.8% of the patients, followed by respiratory tract infection (46.1%). Two pediatric patients presented with both sepsis and meningitis. Nine patients (69.2%) recovered, and death occurred in four patients (30.8%). Susceptibility testing revealed 100% in vitro resistance to most of the antibiotics such as amikacin, aztreonam, cefepime, ceftazidime, colistin, gentamicin, meropenem, and polymyxin B which are used to treat Gram-negative bacterial infections. The isolates were most susceptible to minocycline and piperacillin.Conclusion: E. meningoseptica is an emerging pathogen and is being isolated more frequently now. An expeditious and prompt institution of appropriate therapy is essential because of its inherent resistance to many antimicrobial agents commonly used to treat infections caused by Gram-negative bacteria

A study comparing the change in drug utilization pattern in medical intensive care unit of a tertiary care hospital in seven years

Background: Medical intensive care unit is a type of intensive care unit that takes care of a range of medical illnesses with patients who are seriously ill and/or suffer from severe chronic illnesses. These patients are usually prescribed multiple drugs. Use of antimicrobial agents and injectable medications in setting of MICU is high as compared with other class of drugs and other hospital settings respectively. Periodic evaluation of drug utilization pattern needs to be done to enable suitable modifications in prescription of drugs to increase the therapeutic benefit and decrease the adverse effects. There could be changes in drug utilization pattern due to changes in disease pattern, development of newer drugs, resistance to antimicrobial agents. Hence comparison of past and present data needs to be done to find out the changes that occurred in drug utilization pattern over the years. Methods: Data was collected from June 2021 to Dec 2021 for prospective arm and June 2014 to December 2014 for retrospective arm was obtained from MICU of tertiary care hospital and Medical Record Department. Drug utilization pattern was analysed and compared with appropriate statistical tests. Results: Most common cause of MICU admission was infective diseases (71% and 67% respectively in retrospective and prospective arm). The drug prescribed frequently was pantoprazole and antimicrobial was ceftriaxone in both the study arms. Half of the drugs were prescribed by generic names in both arms. Conclusions: There was no change observed in drug utilization pattern and disease pattern in patients admitted to medical intensive care unit over the years in our institute

Security Enhancement in Cloud System by Anonymous Request Access

Cloud computing is a computing technology or information technology architecture used by organization or individuals. It launches data storage and interactive paradigm with some advantages like on-demand self-services, ubiquitous network access. Due to popularity of cloud services, security and privacy becomes major issue. There is the issue of legitimate responsibility for information (If a client stores some information in the cloud, can the cloud supplier benefit from it?). Numerous Terms of Service assentions are quiet on the topic of proprietorship. Physical control of the PC hardware (private cloud) is more secure than having the gear off site and under another person's control (open cloud). This conveys awesome motivation to open distributed computing administration suppliers to organize building and keeping up solid administration of secure administration. This paper addresses design of proposed system