On the chemical composition of cosmic rays of highest energy

We present arguments aiming at reconciling apparently contradictory results concerning the chemical composition of cosmic rays of highest energy, coming recently from the Auger and HiRes collaborations. In particular, we argue that the energy dependence of the mean value and root mean square fluctuation of shower maxima distributions observed by the Auger experiment are not necessarily caused by the change of nuclear composition of primary cosmic rays. They could also be caused by the change of distribution of the first interaction point in the cascade. A new observable, in which this influence is strongly suppressed, is proposed and tested.Comment: Version accepted by J.Phys. G (2011

Intriguing feature of multiplicity distributions

Multiplicity distributions, P(N), provide valuable information on the mechanism of the production process. We argue that the observed P(N) contain more information (located in the small N region) than expected and used so far. We demonstrate that it can be retrieved by analysing specific combinations of the experimentally measured values of P(N) which we call {it modified combinants, Cj, and which show distinct oscillatory behavior, not observed in the usual phenomenological forms of the P(N) used to fit data. We discuss the possible sources of these oscillations and their impact on our understanding of the multiparticle production mechanism.Comment: Invited talk presented at XLVIII International Symposium on Multiparticle Dynamics (ISMD2018), 3 to 7 September 2018, Singapore; 10 pages, 6 figures. To be published in EPJ Web of Conference

Transverse momentum versus multiplicity fluctuations in high-energy nuclear collisions

We discuss recently measured event-by-event fluctuations of transverse momentum and of multiplicity in relativistic heavy-ion collisions. It is shown that the non-monotonic behavior of the p_T-fluctuations as a function of collision centrality can be fully explained by the observed non-monotonic multiplicity fluctuations. A possible mechanism responsible for the multiplicity fluctuations is also considered.Comment: 5 pages, 3 figures, revised & extended, to appear in Phys. Rev.

Validation of differential pulse polarographic method of ascorbic acid assay in food – Comparison with the chromatographic reference method

The objective of the study was to demonstrate the applicability of differential pulse polarography (DPP) technique of the ascorbic acid (AA) assay for the analysis of food samples with various matrices. The following validation parameters were determined: selectivity, linearity, precision, accuracy, limit of detection, and limit of quantification. The limits of detection and quantification were 0.17 and 0.5 mg ascorbic acid per 100 g food, respectively. The average recovery of added ascorbic acid from all matrices was 96.3–103.6%. The values of the coefficient of variation calculated on the basis of AA contents for food matrices were in the range 2–9.26% and Horrat values were 0.37–1.10. Ascorbic acid values of the samples obtained from the polarographic method were compared with those obtained from high-performance liquid chromatography with diode-array detection (HPLC-DAD) used as the reference method. The analytical parameters determined showed that the polarographic method was equivalent to the chromatographic method. Validation of the polarographic method of ascorbic acid assay indicates that it can be applied for the analysis of ascorbic acid concentration in food products that do not contain isoascorbic acid. This means that the method can be recommended for routine determinations

Use of sweeteners in osmotic pretreatment before freeze-drying of pear and pineapple

The aim of the study was to analyse the influence of the type of osmotic substance (sucrose, glucose, xylitol, trehalose, and sorbitol) on the physicochemical properties of freeze-dried fruit (pear and pineapple). Controlling the functional properties of freeze-dried fruit after osmotic dehydration with aqueous solutions at water activity of a w=0.90 is presented. Decrease in the water adsorption index (WAI) was recorded for all dehydrated samples. The largest decrease (for pears and pineapples by 25 and 65%, respectively) was observed in osmoactive solutions containing trehalose. Considerable increase in the FAI was recorded in samples of dehydrated pineapple. In osmoactive trehalose solutions that increase hardly reached 46%, whereas in sorbitol and xylitol its value elevated to 39% and 13%, respectively. Regardless of the osmoactive sweetener applied prior to freeze-drying, an increase in specific surface area (SBET) of dried materials was observed. For dehydrated pears, SBET ranged from 96 to 697 m2 g−1, and for pineapple, from 115 to 938 m2 g−1. Osmotic dehydration before lyophilisation of fruit samples weakened rehydration relative to the control. The dehydration carried out with osmoactive sweeteners, that is, sorbitol, xylitol, and trehalose, allows obtaining a product with good functional properties that can be successfully used for supplementation of dietary products, in particular for diabetics

Single-Exponential FPT Algorithms for Enumerating Secluded F\mathcal{F}-Free Subgraphs and Deleting to Scattered Graph Classes

The celebrated notion of important separators bounds the number of small $(S,T)$-separators in a graph which are 'farthest from $S$' in a technical sense. In this paper, we introduce a generalization of this powerful algorithmic primitive that is phrased in terms of $k$-secluded vertex sets: sets with an open neighborhood of size at most $k$. In this terminology, the bound on important separators says that there are at most $4^k$ maximal $k$-secluded connected vertex sets $C$ containing $S$ but disjoint from $T$. We generalize this statement significantly: even when we demand that $G[C]$ avoids a finite set $\mathcal{F}$ of forbidden induced subgraphs, the number of such maximal subgraphs is $2^{O(k)}$ and they can be enumerated efficiently. This allows us to make significant improvements for two problems from the literature. Our first application concerns the 'Connected $k$-Secluded $\mathcal{F}$-free subgraph' problem, where $\mathcal{F}$ is a finite set of forbidden induced subgraphs. Given a graph in which each vertex has a positive integer weight, the problem asks to find a maximum-weight connected $k$-secluded vertex set $C \subseteq V(G)$ such that $G[C]$ does not contain an induced subgraph isomorphic to any $F \in \mathcal{F}$. The parameterization by $k$ is known to be solvable in triple-exponential time via the technique of recursive understanding, which we improve to single-exponential. Our second application concerns the deletion problem to scattered graph classes. Here, the task is to find a vertex set of size at most $k$ whose removal yields a graph whose each connected component belongs to one of the prescribed graph classes $\Pi_1, \ldots, \Pi_d$. We obtain a single-exponential algorithm whenever each class $\Pi_i$ is characterized by a finite number of forbidden induced subgraphs. This generalizes and improves upon earlier results in the literature.Comment: To appear at ISAAC'2

Immunohistochemical characteristics of porcine intrahepatic nerves under physiological conditions and after bisphenol A administration

Background: The neurochemistry of hepatic nerve fibres was investigated in large animal models after dietary exposure to the endocrine disrupting compound known as bisphenol A (BPA).   Materials and methods: Antibodies against neuronal peptides were used to study changes in hepatic nerve fibres after exposure to BPA at varying concentrations using standard immunofluorescence techniques. The neuropeptides investigated were substance P (SP), galanin (GAL), pituitary adenylate cyclase activating polypeptide (PACAP), calcitonin gene regulated peptide (CGRP) and cocaine and amphetamine regulated transcript (CART). Immunoreactive nerve fibres were counted in multiple sections of the liver and among multiple animals at varying exposure levels. The data was pooled and presented as mean ± standard error of the mean.   Results: It was found that all of the nerve fibres investigated showed upregulation of these neural markers after BPA exposure, even at exposure levels currently considered to be safe. These results show very dramatic increases in nerve fibres containing the above-mentioned neuropeptides and the altered neurochemical levels may be causing a range of pathophysiological states if the trend of over-expression is extrapolated to developing humans.   Conclusions: This may have serious implications for children and young adults who are exposed to this very common plastic polymer, if the same trends are occurring in humans

Printability study of metal ion crosslinked PEG-catechol based inks

In this paper we explore the printability of reversible networks formed by catechol functionalized PEG solutions and metal cations (Al3+, Fe3+ or V3+). The printability and shape fidelity were dependent on the ink composition (metal ion type, pH, PEG molecular weight) and printing parameters (extrusion pressure and printing speed). The relaxation time, recovery rate and viscosity of the inks were analyzed in rheology studies and correlated with thermodynamic and ligand exchange kinetic constants of the dynamic bonds and the printing performance (i.e. shape fidelity of the printed structures). The relevance of the relaxation time and ligand exchange kinetics for printability was demonstrated. Cells seeded on the materials crosslinked with Al3+, Fe3+ ions were viable and revealed well-spread morphologies during 7 day culture, indicating the potential of the formulations to be used as inks for cell encapsulation. The proposed dynamic ink design offers significant flexibility for 3D bioprinting, and enables straightforward adjustment of the printable formulation to meet application-specific needs