Neurons Controlling Voluntary Vocalization in the Macaque Ventral Premotor Cortex

The voluntary control of phonation is a crucial achievement in the evolution of speech. In humans, ventral premotor cortex (PMv) and Broca's area are known to be involved in voluntary phonation. In contrast, no neurophysiological data are available about the role of the oro-facial sector of nonhuman primates PMv in this function. In order to address this issue, we recorded PMv neurons from two monkeys trained to emit coo-calls. Results showed that a population of motor neurons specifically fire during vocalization. About two thirds of them discharged before sound onset, while the remaining were time-locked with it. The response of vocalization-selective neurons was present only during conditioned (voluntary) but not spontaneous (emotional) sound emission. These data suggest that the control of vocal production exerted by PMv neurons constitutes a newly emerging property in the monkey lineage, shedding light on the evolution of phonation-based communication from a nonhuman primate species

Deuring for the people: Supersingular elliptic curves with prescribed endomorphism ring in general characteristic

Constructing a supersingular elliptic curve whose endomorphism ring is isomorphic to a given quaternion maximal order (one direction of the Deuring correspondence) is known to be polynomial-time assuming the generalized Riemann hypothesis [KLPT14; Wes21], but notoriously daunting in practice when not working over carefully selected base fields. \nIn this work, we speed up the computation of the Deuring correspondence in general characteristic, i.e., without assuming any special form of the characteristic. Our algorithm follows the same overall strategy as earlier works, but we add simple (yet effective) optimizations to multiple subroutines to significantly improve the practical performance of the method. \nTo demonstrate the impact of our improvements, we show that our implementation achieves highly practical running times even for examples of cryptographic size. One implication of these findings is that cryptographic security reductions based on KLPT-derived algorithms (such as [EHLMP18; Wes22]) have become tighter, and therefore more meaningful in practice. \nAnother is the pure bliss of fast(er) computer algebra: We provide a Sage implementation which works for general primes and includes many necessary tools for computational number theorists\' and cryptographers\' needs when working with endomorphism rings of supersingular elliptic curves. This includes the KLPT algorithm, translation of ideals to isogenies, and finding supersingular elliptic curves with known endomorphism ring for general primes. \nFinally, the Deuring correspondence has recently received increased interest because of its role in the SQISign signature scheme [DeF+20]. We provide a short and self-contained summary of the state-of-the-art algorithms without going into any of the cryptographic intricacies of SQISign

PENANAMAN JIWA NASIONALISME SEJAK DINI MELALUI SEMANGAT PANCASILA DI SEKOLAH INDONESIA KUALA LUMPUR

Jiwa nasionalisme sangat perlu ditanamkan sejak dini sebagai upaya perwujudan rasa cinta masyarakat terhadap tanah air. Permasalahan utama pendidikan di luar negeri adalah terjadinya gempuran budaya dan tantangan globalisasi yang tidak terelakkan. Mengatasi permasalahan tersebut perlu dilakukan sosialisasi untuk meningkatkan jiwa nasionalisme salah satunya melalui semangat pancasila. Sosialisasi ini diharapkan memberikan kontribusi pada siswa/i untuk lebih memiliki semangat nasionalisme sehingga bangga sebagai bangsa Indonesia dan berjiwa pancasila. Metode pelaksanaan pengabdian dilakukan dengan melakukan sosialisasi nilai-nilai pancasila dan implementasinya dalam kehidupan sehari-hari dan evaluasi hasil sosialisasi. Hasil sosialisasi ini didapatkan hasil sebelum dan sesudah sosialisasi. Pada aspek nilai pancasila terjadi peningkatan pemahaman dari rata-rata 81% menjadi rata-rata 98%, sedangkan aspek impelentasi pancasila terjadi peningkatan pemahaman dari rata-rata 84% menjadi rata-rata 94%

Associations among the parent–adolescent relationship, aggression and delinquency in different ethnic groups: a replication across two Dutch samples

Background: The aim of the present study is to examine whether the patterns of association between the quality of the parent-adolescent relationship on the one hand, and aggression and delinquency on the other hand, are the same for boys and girls of Dutch and Moroccan origin living in the Netherlands. Since inconsistent results have been found previously, the present study tests the replicability of the model of associations in two different Dutch samples of adolescents. Method: Study 1 included 288 adolescents (M age = 14.9, range 12-17 years) all attending lower secondary education. Study 2 included 306 adolescents (M age = 13.2, range = 12-15 years) who were part of a larger community sample with oversampling of at risk adolescents. Results: Multigroup structural analyses showed that neither in Study 1 nor in Study 2 ethnic or gender differences were found in the patterns of associations between support, autonomy, disclosure, and negativity in the parent-adolescent relationship and aggression and delinquency. The patterns were largely similar for both studies. Mainly negative quality of the relationship in both studies was found to be strongly related to both aggression and delinquency. Discussion: Results show that family processes that affect adolescent development, show a large degree of universality across gender and ethnicity

Recent patterns in chronic disease mortality in remote living Indigenous Australians

Background: Despite the well-recognised Indigenous-non-Indigenous health disparity, some reports suggest improvements in Indigenous mortality. Our aim was to quantify Indigenous mortality in Outer Regional (OR), Remote (R), and Very Remote (VR) areas in New South Wales, Queensland, South Australia, Western Australia, and the Northern Territory and changes in mortality from 1998 to 2005

The correlates of urinary albumin to creatinine ratio (ACR) in a high risk Australian Aboriginal community

Background: Albuminuria marks renal disease and cardiovascular risk. It was estimated to contribute 75% of the risk of all-cause natural death in one Aboriginal group. The urine albumin/creatinine ratio (ACR) is commonly used as an index of albuminuria. This study aims to examine the associations between demographic factors, anthropometric index, blood pressure, lipid-protein measurements and other biomarkers and albuminuria in a cross-sectional study in a high-risk Australian Aboriginal population. The models will be evaluated for albuminuria at or above the microalbuminuria threshold, and at or above the "overt albuminuria" threshold with the potential to distinguish associations they have in common and those that differ

Global Perspectives on Task Shifting and Task Sharing in Neurosurgery.

BACKGROUND: Neurosurgical task shifting and task sharing (TS/S), delegating clinical care to non-neurosurgeons, is ongoing in many hospital systems in which neurosurgeons are scarce. Although TS/S can increase access to treatment, it remains highly controversial. This survey investigated perceptions of neurosurgical TS/S to elucidate whether it is a permissible temporary solution to the global workforce deficit. METHODS: The survey was distributed to a convenience sample of individuals providing neurosurgical care. A digital survey link was distributed through electronic mailing lists of continental neurosurgical societies and various collectives, conference announcements, and social media platforms (July 2018-January 2019). Data were analyzed by descriptive statistics and univariate regression of Likert Scale scores. RESULTS: Survey respondents represented 105 of 194 World Health Organization member countries (54.1%; 391 respondents, 162 from high-income countries and 229 from low- and middle-income countries [LMICs]). The most agreed on statement was that task sharing is preferred to task shifting. There was broad consensus that both task shifting and task sharing should require competency-based evaluation, standardized training endorsed by governing organizations, and maintenance of certification. When perspectives were stratified by income class, LMICs were significantly more likely to agree that task shifting is professionally disruptive to traditional training, task sharing should be a priority where human resources are scarce, and to call for additional TS/S regulation, such as certification and formal consultation with a neurosurgeon (in person or electronic/telemedicine). CONCLUSIONS: Both LMIC and high-income countries agreed that task sharing should be prioritized over task shifting and that additional recommendations and regulations could enhance care. These data invite future discussions on policy and training programs

The Relationship Between Parenting and Delinquency: A Meta-analysis

This meta-analysis of 161 published and unpublished manuscripts was conducted to determine whether the association between parenting and delinquency exists and what the magnitude of this linkage is. The strongest links were found for parental monitoring, psychological control, and negative aspects of support such as rejection and hostility, accounting for up to 11% of the variance in delinquency. Several effect sizes were moderated by parent and child gender, child age, informant on parenting, and delinquency type, indicating that some parenting behaviors are more important for particular contexts or subsamples. Although both dimensions of warmth and support seem to be important, surprisingly very few studies focused on parenting styles. Furthermore, fewer than 20% of the studies focused on parenting behavior of fathers, despite the fact that the effect of poor support by fathers was larger than poor maternal support, particularly for sons. Implications for theory and parenting are discussed

Regional and experiential differences in surgeon preference for the treatment of cervical facet injuries: a case study survey with the AO Spine Cervical Classification Validation Group

Purpose: The management of cervical facet dislocation injuries remains controversial. The main purpose of this investigation was to identify whether a surgeon’s geographic location or years in practice influences their preferred management of traumatic cervical facet dislocation injuries. Methods: A survey was sent to 272 AO Spine members across all geographic regions and with a variety of practice experience. The survey included clinical case scenarios of cervical facet dislocation injuries and asked responders to select preferences among various diagnostic and management options. Results: A total of 189 complete responses were received. Over 50% of responding surgeons in each region elected to initiate management of cervical facet dislocation injuries with an MRI, with 6 case exceptions. Overall, there was considerable agreement between American and European responders regarding management of these injuries, with only 3 cases exhibiting a significant difference. Additionally, results also exhibited considerable management agreement between those with ≤ 10 and > 10 years of practice experience, with only 2 case exceptions noted. Conclusion: More than half of responders, regardless of geographical location or practice experience, identified MRI as a screening imaging modality when managing cervical facet dislocation injuries, regardless of the status of the spinal cord and prior to any additional intervention. Additionally, a majority of surgeons would elect an anterior approach for the surgical management of these injuries. The study found overall agreement in management preferences of cervical facet dislocation injuries around the globe