Feasibility of a self-help web-based intervention targeting young cancer patients with sexual problems and fertility distress

PURPOSE: The purpose of the study is to evaluate the feasibility of a self-help web-based intervention to alleviate sexual problems and fertility distress in adolescents and young adults with cancer. METHODS: Twenty-three persons with cancer (19 women and 4 men, age 18-43, 1-5 years post-diagnosis of lymphoma, breast, gynecologic, central nervous system, or testicular cancer) were recruited to test a 2-month web-based program targeting sexual problems or fertility distress. The programs were organized in modules with educational and behavior change content, including texts, illustrations, exercises, and video vignettes. The program also included a discussion forum and an "ask the expert" forum. In addition, the sexuality program offered two telephone consultations. Feasibility (regarding demand, acceptability, preliminary efficacy, and functionality) was evaluated with the website system data, telephone interviews, continuous online evaluations, and study-specific measures. RESULTS: Fifteen participants completed four modules or more. Most of the program features were used and well accepted by these "committed users." The web-based format enabled flexible use by participants with diverse needs. Preliminary efficacy was indicated by self-reported increased knowledge and skill in handling sexual problems and fertility distress. The website was easy to use and functioned well technically. CONCLUSIONS: The present study indicated that this web-based intervention was feasible for adolescents and young adults with cancer. The effectiveness of the intervention in decreasing sexual problems and fertility distress will be tested in a population-based randomized controlled trial for adolescents and young adults with cancer. TRIAL REGISTRATION: ISRCTN36621459

Single Pass Flow-Through (SPFT) Test Results of Fluidized Bed Steam Reforming (FBSR) Waste Forms used for LAW Immobilization-#12252

ABSTRACT Several supplemental technologies for treating and immobilizing Hanford low activity waste (LAW) are being evaluated. One such immobilization technology being considered is the Fluidized Bed Steam Reforming (FBSR) product, which is granular and will be monolithed into a final waste form. The granular component is composed of insoluble sodium aluminosilicate (NAS) feldspathoid minerals. Production of the FBSR mineral product has been demonstrated at the industrial, engineering, and laboratory scales. Single-Pass Flow-Through (SPFT) tests at various flow rates have been conducted with the granular products fabricated using the engineering-and laboratory-scale methods. Results show that the forward dissolution rate for the engineering-scale mineral product is 0.6 (±0.2)×10 -3 g/m 2 d while the forward dissolution rate for the laboratory-scale mineral product is 1.3 (±0.5)×10 -3 g/m 2 d

Characterization of Material from Wells 299-W10-35 (C7573) and 299-W14-74 (C7024)

The objective of this work was to characterize material accumulating on wells 299-W10-35 (C7573) and 299-W14-74 (C7024) to determine the type of material (i.e., chemical or biological) and, if the material is biological, to identify the microorganisms present