Optimal Round Robin CPU Scheduling Algorithm Using Manhattan Distance

In Round Robin Scheduling the time quantum is fixed and then processes are scheduled such that no process get CPU time more than one time quantum in one go. The performance of Round robin CPU scheduling algorithm is entirely dependent on the time quantum selected. If time quantum is too large, the response time of the processes is too much which may not be tolerated in interactive environment. If time quantum is too small, it causes unnecessarily frequent context switch leading to more overheads resulting in less throughput. In this paper a method using Manhattan distance has been proposed that decides a quantum value. The computation of the time quantum value is done by the distance or difference between the highest burst time and lowest burst time. The experimental analysis also shows that this algorithm performs better than RR algorithm and by reducing number of context switches, reducing average waiting time and also the average turna round time

ANTICANCER ACTIVITY OF PLANT PROTEIN AGAINST DALTON'S LYMPHOMA ASCITES TUMOR CELL LINES

Objective: Tabernaemontana divaricata (Td) is commonly used plants for the treatment of inflammatory, anticancer, and diabetics. The main objective of this study is to assess the antitumor and antioxidant activity of Td in mice model.Methods: Antitumor activity of TdPf extract (52 µg/ml) is evaluated against Dalton's lymphoma ascites (DLA) tumor mice. After 24 hrs of tumor inoculation, the extract is administered daily for 15 and 60 days. After administration of the lost dose followed by 18 hrs fasting, mice are sacrificed for observation of antitumor activity. Antitumor activity is assessed by monitoring the liver marker enzyme, lipid peroxidation effect on antioxidant enzyme levels, and histopathological evidence.Results: The results showed that the protein extract of Td animals restored the antioxidant enzymes when compared to the mice of the DLA control group.Conclusion: The findings indicate that the extract of plant protein has antitumor activity by preventing the lipid peroxidation and thereby promoting the antioxidant systems in DLA induced mice. And hence, it is evident that these extract could be a natural anticancer agent for the human health.Keywords: Dalton's lymphoma ascites, Antitumor, Tabernaemontana divaricata, Lipid peroxidation antioxidant

Enrollment in YFV Vaccine Trial: An Evaluation of Recruitment Outcomes Associated with a Randomized Controlled Double-Blind Trial of a Live Attenuated Yellow Fever Vaccine

This investigation evaluated several factors associated with diverse participant enrollment of a clinical trial assessing safety, immunogenicity, and comparative viremia associated with administration of 17-D live, attenuated yellow fever vaccine given alone or in combination with human immune globulin. We obtained baseline participant information (e.g., sociodemographic, medical) and followed recruitment outcomes from 2005 to 2007. Of 355 potential Yellow Fever vaccine study participants, 231 cases were analyzed. Strong interest in study participation was observed among racial and ethnically diverse persons with 36.34% eligible following initial study screening, resulting in 18.75% enrollment. The percentage of white participants increased from 63.66% (prescreened sample) to 81.25% (enrollment group). The regression model was significant with white race as a predictor of enrollment (OR=2.744, 95% CI=1.415-5.320, p=0.003).In addition, persons were more likely to enroll via direct outreach and referral mechanisms compared to mass advertising (OR=2.433, 95% CI=1.102-5.369). The findings indicate that racially diverse populations can be recruited to vaccine clinical trials, yet actual enrollment may not reflect that diversit

CA 125 is a better marker to differentiate endometrial cancer and abnormal uterine bleeding

Background: Incidence of endometrial cancer in India is increasing due to lifestyle changes and obesity. As 5 year survival rate of cancer confined to uterus is good, there is need for serum tumor marker for early diagnosis. This study was designed to identify a tumor marker which differentiate endometrial carcinoma and abnormal uterine bleeding (AUB) because common presentation of endometrial carcinoma is AUB. Objectives: To estimate and compare serum prolactin, Cancer Antigen 125 (CA-125), Cancer Antigen 15-3 (CA15-3), and Carcino embryonic antigen (CEA) levels in patients with endometrial cancer and abnormal uterine bleeding; To evaluate the role of these markers in diagnosing endometrial cancer. Methodology: Thirty eight patients with endometrial cancer and 40 patients with AUB were recruited in this study. Serum prolactin, CA 125, CEA, and CA 15-3 levels were estimated in both groups. Results: The levels of CA 15-3, CA 125, CEA, and prolactin were increased in endometrial carcinoma patients, on comparison with AUB patients. CA 125 alone was found to be a better marker to detect endometrial cancer with 52.63% sensitivity, 80.00% specificity. Conclusion: As individual tumor marker, serum CA 125 has the ability to detect endometrial cancer in patients with abnormal uterine bleeding.Keywords: CA-125 antigen, CA 15-3, carcino embryonic antigen, endometrial carcinoma, prolactin, tumor marker, abnormal uterine bleeding

Wire less Power Theft Monitoring Using GSM

Developing countries faces widespread theft of power from government owned power utilities. So the aim of this project is to display the power theft area of the distribution transformer and raise an alarm. Here for the practical purpose transformers, source energy meter, household load, energy meter are used for measuring real loads along with wired link.The power theft area of the distribution transformer at substation is obtained by calculating the real consuming power by the energy meter and the main power at the distribution transformer. That means the real consumption of all users must be equals to the total power delivered by the transformer. The difference must be analyzed by the controller by calculating both powers. If the difference is within 2 to 3% variation (transmission losses are concerned) the system raises no error otherwise it will generates error with an alarm and sends message along with transformer location information to the authority through GSM modem and displays in the corresponding substation along with alarm

Machine Learning Based Classification Model for Network Traffic Anomaly Detection

In current days, cloud environments are facing a huge challenge from the attackers in terms of various attacks thrown to the cloud service providers. In both industry and academics, the problem of detection and mitigation of DDoS attacks is now a challenging issue. Detecting Distributed Denial of Service (DDos) threats is mainly a classification problem that can be addressed using data mining, machine learning and deep learning techniques. DDoS attacks can occur in any of the seven-layer OSI model's network. Hence, detecting the DDoS attacks is an important task for cloud service providers to overcome dangerous attacks and loss incurred to stake holders and also the provider

Controller Implementation for PV Interconnection Based Three-Phase UPS Systems Operating Under Highly Nonlinear Loads

In this paper we have multi functional converters to inter connect the both the dc and ac grids to handle power quality issues of the micro-grids. Multifunctional inverters can not only interface the renewable energy resource into the utility grid, but also can compensate the harmonic and reactive current in the micro-grid as an auxiliary service. Therefore, to enhance the power quality of the micro-grid by optimal utilization of the limited and valuable capacity becomes a technical challenge. In this paper, two optimal control objectives of MFGTIs are presented based on a comprehensive power quality evaluation algorithm by means of Analytic Hierarchy Process (AHP) theory. The two proposed strategies are analyzed about the powers and voltage and currents as results, and the paper also discusses how to use them in practice for the best performance. Simulation of proposed svpwm verifies the feasibility of the proposed optimal control strategies

In Vitro plant regeneration of Cucumber (Cucumis sativum (L.) from cotyledon and hypocotyl explants

ABSTRACT In vitro plantlet regeneration has been obtained from 15-20days old seedling cotyledon and hypocotyl segments of Cucumis sativus (L.) were examined using various phytoharmons individually and in combination on Murashige and Skoo

Kloniranje, ekspresija i karakterizacija paraflagelarnog gena Rod 2 bičaša Trypanosoma evansi

Paraflagellar rod is the major structural component of the trypanosomatid flagellum and is identified as a complex lattice of filaments which runs parallel to the axoneme throughout most of the flagellar length. The present study was carried out to investigate the existence of the paraflagellar rod (PFR 2) gene in Trypanosoma evansi infecting Indian cattle. Local isolates of T. evansi collected from naturally infected cow were multiplied in Wistar rats. Complementary DNA (cDNA) was synthesized from the RNA of host cell free T. evansi parasites by reverse transcription. The gel purified PCR product (PFR 2 gene of T. evansi) was cloned into the pTZ57R/T vector system. The nucleotide sequence of the PFR 2 gene of the T. evansi S.V.V.U. isolate (Accession No. KT277497) obtained in the present study revealed 100% homology with T. evansi China isolate and 99% homology with T. evansi Izatnagar and Bikaner isolates. The recombinant protein was sub-cloned into pET 32a and expressed in the BL21 (DE3) pLysS expression system. The PFR 2 gene of T. evansi S.V.V.U. isolate was further characterized by determination of its protein profile with SDS-PAGE and western blotting. Indirect ELISA was optimized for detection of the specific antibody titre against the recombinant protein of the PFR 2 gene of T. evansi. In the kinetoplastid species the PFR 2 gene is highly conserved. Therefore the PFR 2 gene was suggested as a vaccine candidate, as well as a diagnostic antigen.Paraflagelarni štapić glavna je strukturna komponenta tripanosomskog biča i dio je kompleksa filamenaza koji teku paralelno s aksonemom duž biča. Istraživanje je provedeno kako bi se ispitalo postojanje paraflagelarnog gena Rod 2 (PFR2) u bičaša Trypanosoma evansi koji invadira goveda u Indiji. Lokalni izolat T. evansi prikupljen od prirodno invadiranih krava umnožen je u Wistar štakora. Komplementarna DNA (cDNA) sintetizirana je iz RNA obrnutom transkripcijom iz stanica neinvadiranih nositelja T. evansi parazita. Pročišćeni PCR produkt (gen PFR2 bičaša T. evansi) kloniran je u vektorski sustav pTZ57R/T. Nukleotidna sekvencija gena PFR2 bičaša T. evansi, izolat S.V.V.U. (pristupni broj KT277497) dobivena u ovom istraživanju pokazala je 100 %-tnu sličnost s izolatom T. evansi China i 99 %-tnu s izolatom T. evansi Izatnagar i Bikaner. Rekombinantni protein ponovno je kloniran u sustavu pET 32a i prikazan u sustavu BL21 (DE3) pLysS. Gen PFR2 bičaša T. evansi, izolat S.V.V.U. dalje je karakteriziran određivanjem proteinskog profila metodama SDS-PAGE i Western blotting. Indirektni test ELISA optimiziran je za dokaz titra specifičnih protutijela za rekombinantni protein gena PFR2 bičaša T. evansi. U kinetoplastida gen PFR2 izrazito je očuvan. Stoga bi se gen PFR2 mogao upotrijebiti za cjepivo te kao dijagnostički antigen

EXPERIMENTAL TOXICITY STUDIES OF SALMONELLA SEROVARS ISOLATED FROM PIGS, IN MICE AND GERMINATING SEEDS

ABSTRACT Experimental studies on the effects produced b