Minimum output entropy of bosonic channels: a conjecture

The von Neumann entropy at the output of a bosonic channel with thermal noise is analyzed. Coherent-state inputs are conjectured to minimize this output entropy. Physical and mathematical evidence in support of the conjecture is provided. A stronger conjecture--that output states resulting from coherent-state inputs majorize the output states from other inputs--is also discussed.Comment: 15 pages, 12 figure

Additivity properties of a Gaussian Channel

The Amosov-Holevo-Werner conjecture implies the additivity of the minimum Re'nyi entropies at the output of a channel. The conjecture is proven true for all Re'nyi entropies of integer order greater than two in a class of Gaussian bosonic channel where the input signal is randomly displaced or where it is coupled linearly to an external environment.Comment: 9 pages, 1 figure (minor error present in the published version corrected

Broadband channel capacities

We study the communication capacities of bosonic broadband channels in the presence of different sources of noise. In particular we analyze lossy channels in presence of white noise and thermal bath. In this context, we provide a numerical solution for the entanglement assisted capacity and upper and lower bounds for the classical and quantum capacities.Comment: 11 pages, 7 figures, 3 table

Classical capacity of the lossy bosonic channel: the exact solution

The classical capacity of the lossy bosonic channel is calculated exactly. It is shown that its Holevo information is not superadditive, and that a coherent-state encoding achieves capacity. The capacity of far-field, free-space optical communications is given as an example.Comment: 4 pages, 2 figures (revised version

Proposed Experiment in Two-Qubit Linear Optical Photonic Gates for Maximal Success Rates

Here we propose an experiment in Linear Optical Quantum Computing (LOQC) using the framework first developed by Knill, Laflamme, and Milburn. This experiment will test the ideas of the authors' previous work on imperfect LOQC gates using number-resolving photon detectors. We suggest a relatively simple physical apparatus capable of producing CZ gates with controllable fidelity less than 1 and success rates higher than the current theoretical maximum (S=2/27) for perfect fidelity. These experimental setups are within the reach of many experimental groups and would provide an interesting experiment in photonic quantum computing.Comment: 9 pages, 3 figure

Membrane Potential and Bicarbonate Secretion in Isolated Interlobular Ducts from Guinea-pig Pancreas

The interlobular duct cells of the guinea-pig pancreas secrete HCO3− across their luminal membrane into a HCO3−-rich (125 mM) luminal fluid against a sixfold concentration gradient. Since HCO3− transport cannot be achieved by luminal Cl−/HCO3− exchange under these conditions, we have investigated the possibility that it is mediated by an anion conductance. To determine whether the electrochemical potential gradient across the luminal membrane would favor HCO3− efflux, we have measured the intracellular potential (Vm) in microperfused, interlobular duct segments under various physiological conditions. When the lumen was perfused with a 124 mM Cl−-25 mM HCO3− solution, a condition similar to the basal state, the resting potential was approximately −60 mV. Stimulation with dbcAMP or secretin caused a transient hyperpolarization (∼5 mV) due to activation of electrogenic Na+-HCO3− cotransport at the basolateral membrane. This was followed by depolarization to a steady-state value of approximately −50 mV as a result of anion efflux across the luminal membrane. Raising the luminal HCO3− concentration to 125 mM caused a hyperpolarization (∼10 mV) in both stimulated and unstimulated ducts. These results can be explained by a model in which the depolarizing effect of Cl− efflux across the luminal membrane is minimized by the depletion of intracellular Cl− and offset by the hyperpolarizing effects of Na+-HCO3− cotransport at the basolateral membrane. The net effect is a luminally directed electrochemical potential gradient for HCO3− that is sustained during maximal stimulation. Our calculations indicate that the electrodiffusive efflux of HCO3− to the lumen via CFTR, driven by this gradient, would be sufficient to fully account for the observed secretory flux of HCO3−

One-mode Bosonic Gaussian channels: a full weak-degradability classification

A complete degradability analysis of one-mode Gaussian Bosonic channels is presented. We show that apart from the class of channels which are unitarily equivalent to the channels with additive classical noise, these maps can be characterized in terms of weak- and/or anti-degradability. Furthermore a new set of channels which have null quantum capacity is identified. This is done by exploiting the composition rules of one-mode Gaussian maps and the fact that anti-degradable channels can not be used to transfer quantum information.Comment: 23 pages, 3 figure

Reduction of HbA1c levels by fucoxanthin-enriched akamoku oil possibly involves the thrifty allele of uncoupling protein 1 (UCP1): a randomised controlled trial in normal-weight and obese Japanese adults

海藻由来のカロテノイド色素であるフコキサンチンの摂取はHbA1cを改善し，その効果は肥満や糖尿病発症のリスクが高いUCP1-3826A/G多型（G/G型）保有者において著しいことを示した

Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer

Dendrimers are structurally well-defined, synthetic polymers with sizes and physicochemical properties often resembling those of biomacromolecules (e.g. proteins). As a result they are promising candidates for peptide-based vaccine delivery platforms. Herein, we established a synthetic pathway to conjugate a human papillomavirus (HPV) E7 protein-derived peptide antigen to a star-polymer to create a macromolecular vaccine candidate to treat HPV-related cancers. These conjugates were able to reduce tumor growth and eradicate E7-expressing TC-1 tumors in mice after a single immunization, without the help of any external adjuvant