The Neuropsychiatric Factor in Allergic Disease

A concept of the causation of allergic disease herewith is presented in which, in addition to the allergic factors, emotional states and psychic stimuli are introduced as integral parts of every case. The adoption of the terms intrinsic for the neuropsychiatric factors and extrinsic for the organic factors in the production of allergic disease is suggested

Discovery of low mass objects in Taurus

In infrared (2.2 micron, K-band) search of small regions (25 in square) near 26 members of the Taurus star-forming association has revealed 20 dim (K = 13-16 mag) stellar objects near 13 of them. Of these 20 objects, 9 are exceptionally red. It is argued that these 9 are probably also Taurus members. From the luminosities (0.4 to 4 times 10 the -3 power luminosity) and ages (estimated at 10(exp 6) years), masses can be determined by reference to theoretical low-mass cooling curves. The masses are in the range 0.005 to 0.015 solar mass, i.e., low-mass brown dwarfs. Proper motion studies of 7 of the objects visible on the POSS plates conducted by Burton Jones establish that 4 are highly probable Taurus members while 1 is a possible member

Does academic self-concept predict further and higher education participation?

Despite the major increase in university student numbers in recent years there remains a strong negative socio-economic gradient in participation. The main reason for these differences has been shown to be educational factors, including prior attainment, family background and perceptions about costs and returns to education. In this paper, we examine the role of young people’s belief in their own academic ability (academic self-concept) as a way to explain differences in university participation rates. Using Next Steps data, we examine whether young people with higher academic self-concept are more likely to study A Levels, participate in further education and attend university. For those who do attend university, we examine whether young people with higher self-belief attend high status universities or study high status subjects. Results show that on average, controlling for prior attainment and other background characteristics, having high academic self-concept increases the odds in participating in A Level study, decreases the odds in taking part in further education, increases the odds in taking part in higher education (but the significance level disappears after taking A Levels is taken into account) and increases the odds of studying at a high-status university. While academic self-concept is an important predictor of later educational transitions, it does not entirely account for the social gradient in participation of university, further education or higher education. These findings have important policy implications for higher education participation and widening participation in particular

Is 'First in Family' a Good Indicator for Widening University Participation?

Universities use ‘first in family’ or ‘first generation’ as an indicator to increase the diversity of their student intake, but little is known about whether it is a good indicator of disadvantage. We use nationally representative, longitudinal survey data linked to administrative data from England to provide the first comprehensive analysis of this measure. We employ parametric probability (logit) and non-parametric classification (random forest) models to look at its relative predictive power of university participation and graduation. We find that being first in family is an important barrier to university participation and graduation, over and above other sources of disadvantage. This association seems to operate through the channel of early educational attainment. Our findings indicate that the first in family indicator could be key in efforts to widen participation at universities

Is 'first in family' a good indicator for widening university participation?

Universities use ‘first in family’ or ‘first generation’ as an indicator to increase the diversity of their student intake, but little is known about whether it is a good indicator of disadvantage. We use nationally representative, longitudinal survey data linked to administrative data from England to provide the first comprehensive analysis of this measure. We employ parametric probability (logit) and non-parametric classification (random forest) models to look at its relative predictive power of university participation and graduation. We find that being first in family is an important barrier to university participation and graduation, over and above other sources of disadvantage. This association seems to operate through the channel of early educational attainment. Our findings indicate that the first in family indicator could be key in efforts to widen participation at universities

'First in Family' University Graduates in England

Universities around the world are attempting to increase the diversity of their student population. This includes individuals who are 'first in family' (FiF), those who achieve a university degree, but whose (step) parents did not. We provide the first large scale, quantitative evidence on FiF graduates in England using a nationally representative survey linked to administrative education data. We find that FiF young people make up 18 percent of a recent cohort, comprising nearly two-thirds of all university graduates. Comparing individuals with no parental higher education we show that ethnic minorities and those with higher levels of prior attainment are more likely to experience intergenerational educational mobility and become a FiF. Once at university, those who are FiF are more likely to study Law, Economics and Management and less likely to study other Social Sciences, Arts and Humanities than students whose parents are university graduates. We also find evidence that FiF students are less likely to graduate from elite universities and have a higher probability of dropping out, even after prior educational attainment, individual characteristics and socio-economic status are taken into account

Moving on up: 'first in family' university graduates in England

This paper provides the first quantitative analysis on ‘first in family’ (FiF) university graduates in the UK. Using a nationally representative dataset that covers a recent cohort in England, we identify the proportion of FiF young people at age 25 as 18%, comprising nearly two-thirds of university graduates. Comparing groups with no parental higher education we find that ethnic minorities and those with higher levels of prior attainment are more likely to become a FiF, while those who are FiF are more likely to study Law, Economics and Management and less likely to study other Social Sciences, Arts and Humanities than students whose parents are graduated. We also find evidence that FiF students are less likely to graduate from elite universities and are at greater risk of dropout in general, even after prior educational attainment and socioeconomic status are taken into account

Baboon endogenous virus genome. I. Restriction enzyme map of the unintegrated DNA genome of a primate retrovirus

A detailed restriction map was deduced for the genome of an endogenous retrovirus of a higher primate, that of baboon. The cleavage sites for 12 restriction enzymes were mapped. The unintegrated linear viral DNA intermediate that is produced by infection of permissive cells with baboon endogenous virus was isolated. Hybridization with a strong-stop complementary DNA probe demonstrated presence of a terminal repetition in the linear viral DNA. The positions of restriction sites for two particular enzymes, SmaI and XhoI, near each end were consistent with this result and indicated that the length of the repetition is 0.55 +/- 0.01 kilobase. The linear viral DNA had a unique restriction map indicating that it is not a set of random circular permutations of the RNA genome. From hybridization with a 3'-specific probe, the DNA restriction map was aligned relative to the 5'-to-3' orientation of the viral RNA. We observed a minor heterogeneity in a BamHI recognition site 1.95 kilobases from the right end of the linear map

Detection of sulphur in the galactic center

A strong detection at the (SIII) 18.71 micron line is reported for the Galactic Center region, Sgr A West. A line flux of 1.7 + or - 0.2x10 to the -17th power W cm(-2) is found for a 20-arc second beam-size measurement centered on IRS 1. A preliminary analysis indicates that the SIII abundance relative to hydrogen is consistent with the cosmic abundance of sulfur, 1.6x10 to the -5th power, if a filling factor of unity within the known clumps is assumed. However, the sulfur abundance in the Galactic Center may be as much as a factor of 3 overabundant if a filling factor of 0.03 is adopted, a value found to hold for some galactic HII regions

Physical activity in adolescence: cross-national comparisons of levels, distributions and disparities across 52 countries

Introduction: Despite global concerns regarding physical inactivity, limited cross-national evidence exists to compare adolescents’ physical activity participation. We analysed 52 high- and low-middle income countries, with activity undertaken inside and outside of school in 2015. We investigated gender- and socioeconomic-disparities, and additionally examined correlations with country-level indices of physical education (PE) curriculum time allocation, wealth, and income inequality. / Methods: We used the Programme for International Student Assessment (PISA), a nationally representative cross-sectional survey of 15-year-olds (N=347,935). Students reported average attendance (days/week) in PE classes, and the days/week engaged in moderate activity (MPA) and vigorous activity (VPA) outside of school. Both the mean and distributions of outcomes were evaluated, as were gender- and socioeconomic-disparities. Pearson’s correlations (r) between the physical activity outcomes and PE curriculum time allocation, wealth (indexed by GDP) and income inequality (indexed by the Gini coefficient) were calculated. / Results: Activity levels inside and outside of school were higher in Eastern Europe than Western Europe, the Americas, and the Middle East/North Africa. Comparisons of average levels masked potentially important differences in distributions. For example, activity levels inside school showed a bimodal distribution in the US (mean PE class attendance 2.4 days/week; 41.3%, 6.3% and 33.1% of students attended PE classes on 0, 2 and 5 days/week respectively). In contrast, most other countries exhibited more centrally shaped distributions. Pro-male and pro-high socioeconomic disparities were modest for participation inside school, but higher for MPA and VPA outside of school. The magnitude of these also differed markedly by country. Activity in school was weakly positively correlated with PE curriculum time allocation (r=0.33); activity outside of school was strongly negatively correlated with income inequality (e.g. r=-0.69 for MPA). / Conclusion: Our findings reveal extensive cross-country differences in adolescents’ physical activity; in turn, these highlight policy areas that could ultimately improve global adolescent health, such as the incorporation of minimum country-level PE classes, and the targeting of gender- and socioeconomic- disparities in activity conducted outside of school. Our findings also highlight the utility of educational databases such as PISA for use in global population health research