1,077 research outputs found

    Zero Range Process and Multi-Dimensional Random Walks

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    The special limit of the totally asymmetric zero range process of the low-dimensional non-equilibrium statistical mechanics described by the non-Hermitian Hamiltonian is considered. The calculation of the conditional probabilities of the model are based on the algebraic Bethe ansatz approach. We demonstrate that the conditional probabilities may be considered as the generating functions of the random multi-dimensional lattice walks bounded by a hyperplane. This type of walks we call the walks over the multi-dimensional simplicial lattices. The answers for the conditional probability and for the number of random walks in the multi-dimensional simplicial lattice are expressed through the symmetric functions

    Electron-phonon coupling and its evidence in the photoemission spectra of lead

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    We present a detailed study on the influence of strong electron-phonon coupling to the photoemission spectra of lead. Representing the strong-coupling regime of superconductivity, the spectra of lead show characteristic features that demonstrate the correspondence of physical properties in the normal and the superconducting state, as predicted by the Eliashberg theory. These features appear on an energy scale of a few meV and are accessible for photoemission only by using modern spectrometers with high resolution in energy and angle.Comment: 4 pages, 4 figures, accepted for publication in Phys. Rev. Let

    An Implicit Interface Boundary Integral Method for Poisson’s Equation on Arbitrary Domains

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    We propose a simple formulation for constructing boundary integral methods to solve Poisson’s equation on domains with smooth boundaries defined through their signed distance function. Our formulation is based on averaging a family of parameterizations of an integral equation defined on the boundary of the domain, where the integrations are carried out in the level set framework using an appropriate Jacobian. By the coarea formula, the algorithm operates in the Euclidean space and does not require any explicit parameterization of the boundaries. We present numerical results in two and three dimensions

    Improved FTO/NiOx interfaces for inverted planar triple cation perovskite solar cells

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    Front electrodes of fluorine doped tin oxide (FTO) thin films and hole transporting layers of nickel oxide thin films have been combined to fabricate 1.063 cm2 inverted planar solar cells with cesium-containing triple cation perovskites as absorber layers. Using atmospheric pressure chemical vapor deposition FTO layers were obtained with low sheet resistance, decreased root mean squareroughness, increased transmission,and reduced optical haze values compared to a widely used commercial FTO substrate. Cell performance outperformed the equivalent cells fabricated using the commercial FTO. With full illumination under maximumpowerpoint tracking, a stabilized power conversion efficiency of 13.78 % was obtained for the champion device

    Functional modes of proteins are among the most robust ones

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    It is shown that a small subset of modes which are likely to be involved in protein functional motions of large amplitude can be determined by retaining the most robust normal modes obtained using different protein models. This result should prove helpful in the context of several applications proposed recently, like for solving difficult molecular replacement problems or for fitting atomic structures into low-resolution electron density maps. Moreover, it may also pave the way for the development of methods allowing to predict such motions accurately.Comment: 4 pages, 5 figure

    Targeting cancer vasculature via endoglin/CD105: a novel antibody-based diagnostic and therapeutic strategy in solid tumours

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    Endoglin/CD105 is well acknowledged as being the most reliable marker of proliferation of endothelial cells, and it is overexpressed on tumour neovasculature. Our current knowledge of its structure, physiological role, and tissue distribution suggests that targeting of endoglin/CD105 is a novel and powerful diagnostic and therapeutic strategy in human malignancies, through the imaging of tumour-associated angiogenesis and the inhibition of endothelial cell functions related to tumour angiogenesis. Among biotherapeutic agents, monoclonal antibodies have shown a major impact on the clinical course of human malignancies of different histotypes. Along this line, the potential efficacy of anti-endoglin/CD105 antibodies and their derivatives for clinical purposes in cancer is supported by a large body of available pre-clinical in vitro and in vivo data. In this review, the main findings supporting the translation of antibody-based endoglin/CD105 targeting from pre-clinical studies to clinical applications in human cancer are summarized and discussed
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